Media Corpora, Text Mining, and the Sociological Imagination - A Free Software Text Mining Approach to the Framing of Julian Assange by three news agencies using R.TeMiS

International audienceIn this paper, we introduce R.TeMiS, a free software solution aimed at exploring new dimensions in text mining with a particular focus on media framing analysis. R.TeMiS is especially designed to provide help in a) the automation of corpus construction and management procedures based on the use of large media content data bases, and b) the extension of the range of statistical tools available to social scientists exploring texts through R coding (one and two-way tables, time series, hierarchical clustering, correspondence analysis, geographical mapping...). A case study on the media framing of Julian Assange from January 2010 to December 2011 is conducted. It is based on the analysis of a corpus of 667 news dispatches published in English by the three top international news agencies: Agence France-Presse (AFP), Reuters and Associated Press (AP)

Characteristics, management, and prognosis of elderly patients with COVID-19 admitted in the ICU during the first wave: insights from the COVID-ICU study

International audienceBackground: The COVID-19 pandemic is a heavy burden in terms of health care resources. Future decision-making policies require consistent data on the management and prognosis of the older patients (> 70 years old) with COVID-19 admitted in the intensive care unit (ICU). Methods: Characteristics, management, and prognosis of critically ill old patients (> 70 years) were extracted from the international prospective COVID-ICU database. A propensity score weighted-comparison evaluated the impact of intubation upon admission on Day-90 mortality. Results: The analysis included 1199 (28% of the COVID-ICU cohort) patients (median [interquartile] age 74 [72–78] years). Fifty-three percent, 31%, and 16% were 70–74, 75–79, and over 80 years old, respectively. The most frequent comorbidities were chronic hypertension (62%), diabetes (30%), and chronic respiratory disease (25%). Median Clinical Frailty Scale was 3 (2–3). Upon admission, the PaO2/FiO2 ratio was 154 (105–222). 740 (62%) patients were intubated on Day-1 and eventually 938 (78%) during their ICU stay. Overall Day-90 mortality was 46% and reached 67% among the 193 patients over 80 years old. Mortality was higher in older patients, diabetics, and those with a lower PaO2/FiO2 ratio upon admission, cardiovascular dysfunction, and a shorter time between first symptoms and ICU admission. In propensity analysis, early intubation at ICU admission was associated with a significantly higher Day-90 mortality (42% vs 28%; hazard ratio 1.68; 95% CI 1.24–2.27; p < 0·001). Conclusion: Patients over 70 years old represented more than a quarter of the COVID-19 population admitted in the participating ICUs during the first wave. Day-90 mortality was 46%, with dismal outcomes reported for patients older than 80 years or those intubated upon ICU admission