Error intraobservador asociado a medidas antropométricas realizadas por dietistas

Este trabajo se encuentra bajo la licencia Creative Commons Attribution 3.0.[EN] Introduction: Although dietitians play an important role in the anthropometric assessment, reports on measurements made by these health professionals rarely include estimates of measurement error. Aim: To estimate of intraobserver precision for three common anthropometric measurements made by dietitians. Methods: Twenty six measurers performed measurements (upper mid-arm circumference, tricipital and bicipital skinfold) in two times a sample of ten volunteers. Four precision estimates were calculated: the technical error of measurement (TEM), the relative technical error of measurement (rTEM), the coefficient of reliability (R) and the coefficient of variation (CV). Results: For skinfold thickness, rTEM was smaller than 2.2; for circumference, rTEM was smaller than 0.6. The precision to measure skinfolds was lower than the precision to circumference. Anyway, for all measurements R showed a high degree of precision (R > 95). Conclusion: Our results suggest that anthropometric parameters evaluated are sufficiently precise. However, periodical training is necessary to control and minimize the anthropometric measurement error.[ES] Introducción: Aunque los dietistas desempeñan un papel importante en la evaluación antropométrica, las medidas registradas por estos profesionales sanitarios normalmente no incluyen estimación de errores de medida. Objetivo: Estimar la precisión intraobservador de tres medidas antropométricas habituales realizadas por dietistas. Métodos: Veintiséis medidores realizaron en dos ocasiones las medidas (circunferencia media del brazo, pliegue tricipital y bicipital) a una muestra formada por diez voluntarios. Se calcularon cuatro estimaciones de precisión: el error técnico de medida (ETM), el error relativo técnico de medida (ERTM), el coeficiente de fiabilidad (F) y el coeficiente de variación (CV). Resultados: Para los pliegues, el ERTM fue menor de 2,2 y para la circunferencia el ERTM fue menor de 0,6. La precisión para medir los pliegues fue menor que para la circunferencia. De todos modos, para todas las medidas efectuadas la F mostró un elevado grado de precisión (F>95). Conclusión: Nuestros resultados sugieren que los parámetros antropométricos evaluados son lo suficientemente precisos. Sin embargo, es necesario un entrenamiento periódico para controlar y minimizar los errores de las medidas antropométricas

Single nucleotide polymorphisms associated with susceptibility for development of colorectal cancer: Case-control study in a Basque population.

Given the significant population diversity in genetic variation, we aimed to investigate whether single nucleotide polymorphisms (SNPs) previously identified in studies of colorectal cancer (CRC) susceptibility were also relevant to the population of the Basque Country (North of Spain). We genotyped 230 CRC cases and 230 healthy controls for 48 previously reported CRC-susceptibility SNPs. Only the rs6687758 in DUPS10 exhibited a statistically significant association with CRC risk based on the crude analysis. The rs6687758 AG genotype conferred about 2.13-fold increased risk for CRC compared to the AA genotype. Moreover, we found significant associations in cases between smoking status, physical activity, and the rs6687758 SNP. The results of a Genetic Risk Score (GRS) showed that the risk alleles were more frequent in cases than controls and the score was associated with CRC in crude analysis. In conclusion, we have confirmed a CRC susceptibility locus and the existence of associations between modifiable factors and the rs6687758 SNP; moreover, the GRS was associated with CRC. However, further experimental validations are needed to establish the role of this SNP, the function of the gene identified, as well as the contribution of the interaction between environmental factors and this locusto the risk of CRC