61 research outputs found
Maternal vitamin D status in pregnancy and molar incisor hypomineralisation and hypomineralised second primary molars in the offspring at 7â9 years of age:a longitudinal study
Purpose: The study aimed to investigate associations between maternal vitamin D status during pregnancy and molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM) among children. Methods: The study had a longitudinal design using prospectively collected data from 176 mother and child pairs. Mothers were initially recruited in a randomised controlled trial to assess a pregnancy exercise programme. Along with the 7-year follow-up, we invited the children to a dental examination. The exposure variable was maternal serum 25-hydroxyvitamin D in gestational weeks 18â22 and 32â36, categorised as insufficient (< 50 nmol/l) and sufficient (⼠50 nmol/l). Negative binomial hurdle models were used to analyse potential associations between the exposure variables and MIH or HSPM. The models were adjusted for potential confounders. Results: Among the children (7â9 years old), 32% and 22% had at least one tooth with MIH or HSPM, respectively. A significant association was found between insufficient maternal vitamin D measured in gestational weeks 18â22 and the number of affected teeth among those with MIH at 7â9 years (adjusted RR = 1.82, 95% CI 1.13â2.93). Conclusion: Considering any limitations of the present study, it has been shown that insufficient maternal serum vitamin D at mid-pregnancy was associated with a higher number of affected teeth among the offspring with MIH at 7â9 years of age. Further prospective studies are needed to investigate whether this finding is replicable and to clarify the role of maternal vitamin D status during pregnancy and MIH, as well as HSPM, in children
An international intercomparison of stable carbon isotope composition measurements of dissolved inorganic carbon in seawater
We report results of an intercomparison of stable carbon isotope ratio measurements in seawater dissolved inorganic carbon (δ 13CâDIC) which involved 16 participating laboratories from various parts of the world. The intercomparison involved distribution of samples of a Certified Reference Material for seawater DIC concentration and alkalinity and a preserved sample of deep seawater collected at 4000âm in the northeastern Atlantic Ocean. The betweenâlab standard deviation of reported uncorrected values measured with diverse analytical, detection, and calibration methods was 0.11â° (1Ď ). The multiâlab average δ 13CâDIC value reported for the deep seawater sample was consistent within 0.1â° with historical measured values for the same water mass. Application of a correction procedure based on a consensus value for the distributed reference material, improved the betweenâlab standard deviation to 0.06â°. The magnitude of the corrections were similar to those used to correct independent data sets using crossover comparisons, where deep water analyses from different cruises are compared at nearby locations. Our results demonstrate that the accuracy/uncertainty target proposed by the Global Ocean Observing System (Âą0.05â°) is attainable, but only if an aqueous phase reference material for δ 13CâDIC is made available and used by the measurement community. Our results imply that existing Certified Reference Materials used for seawater DIC and alkalinity quality control are suitable for this purpose, if a âCertifiedâ or internally consistent âconsensusâ value for δ 13CâDIC can be assigned to various batches.publishedVersio
Impact of episiotomy on pelvic floor disorders and their influence on women's wellness after the sixth month postpartum: a retrospective study
<p>Abstract</p> <p>Background</p> <p>The role of episiotomy as a protective factor against pelvic floor disorders postpartum has been debated for many years, but its routine use has been hitherto discouraged in the literature. Comparisons between restrictive and routine use of episiotomy in existent literature, however, fail to include any consideration relating to quality of life. The aim of this study, therefore, is to state the role of episiotomy in preserving the perineum from damage, in order to prevent the influence of pelvic floor disorders on women's psycho-physical wellness after the sixth month postpartum.</p> <p>Methods</p> <p>A follow-up telephone interview was performed among 377 primiparous and secondiparous Caucasian women who had a child by spontaneous or operative vaginal delivery in 2006 using a self-created questionnaire and King's Health Questionnaire (KHQ).</p> <p>Results</p> <p>The mean age at delivery was 35.26 (Âą4.68) years and episiotomy was performed in 59.2% of women. Multivariate linear regression shows episiotomy associated to higher quality of life after the sixth month postpartum by correlating with inferior values of King's Health Questionnaire (p < 0.05).</p> <p>Conclusions</p> <p>Episiotomy appears to be a protective factor for women's wellness. Women who had episiotomy and who experienced perineal symptoms have a better psycho-physical health status in the 12.79 months (Âą3.3) follow-up.</p
GlaciStore: understanding Late Cenozoic glaciation and basin processes for the development of secure large scale offshore CO2 storage (North Sea).
The sedimentary strata of the North Sea Basin (NSB) record the glacial and interglacial history of environmental change in the Northern Hemisphere, and are a proposed location for the engineered storage of carbon dioxide (CO2) captured from power plant and industrial sources to reduce greenhouse gas emissions. These aspects interact in the geomechanical and fluid flow domain, as ice sheet dynamics change the properties of potential seal and reservoir rocks that are the prospective geological storage strata for much of Europeâs captured CO2.
The central part of the NSB preserves a unique history of the depositional record spanning at least the last 3 Ma, which also forms the overburden and uppermost seal to the underlying CO2 reservoirs. There is good evidence that these ice sheets created strong feedback loops that subsequently affected the evolution of the Quaternary climate system through complex ocean-atmosphere-cryosphere linkages
The consequences of niche and physiological differentiation of archaeal and bacterial ammonia oxidisers for nitrous oxide emissions
The authors are members of the Nitrous Oxide Research Alliance (NORA), a Marie SkĹodowska-Curie ITN and research project under the EU's seventh framework program (FP7). GN is funded by the AXA Research Fund and CGR by a Royal Society University Research Fellowship (UF150571) and a Natural Environment Research Council (NERC) Standard Grant (NE/K016342/1). The authors would like to thank Dr Robin Walker and the SRUC Craibstone Estate (Aberdeen) for access to the agricultural plots, Dr Alex Douglas for statistical advice and Philipp Schleusner for assisting microcosm construction and sampling.Peer reviewedPublisher PD
Temporal and spatial variability of bone collagen stable carbon and nitrogen isotopic ratios of Norwegian reindeer
Carbon and nitrogen stable isotopes of reindeer (Rangifer tarandus) bones from three Norwegian modern wild reindeer populations (Setesdal Ryfylke, Hardangervidda and Rondane) were used to investigate variations in δ13C and δ15N between, and within, populations. Each of these reindeer populations lives in different climatic and environmental conditions, thus vegetation and climatic conditions could be linked to their stable isotopic signature. Reindeer bones from several archaeological sites on Hardangervidda representing three chronological ranges (275â350 CE, 11th, and 13th century CE) were then analysed for their stable isotopic composition. No statistically significant differences were found within the populations, but the stable isotopic values differed between populations. Subsequently, these stable isotopic values were used to infer modern climatic conditions to sub-fossil palaeoenvironmental conditions on Hardangervidda.1. Introduction 2. Material and methods 2.1. Material 2.2. Climate 2.3. Sample preparation and analysis 2.4. Statistical analyses 3. Results 3.1. Collagen quality 3.2. Effect of lipid extraction on stable isotopic composition 3.3. Differences among skeletal elements 3.4. Spatial differences 3.5. Temporal differences 3.6. Differences among age groups 3.7. Differences between sexes 4. Discussion 5. Conclusion
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