Does More And Better Information Enhance Student Performance On Marketing Projects?

There is some controversy over the amount of guidance students need to complete course projects.  One school of thought argues that students should have maximum information at their disposal, resulting in a better learning process and thus a better project.  The other school of thought suggests that by giving the students too much guidance, the professor is stifling their creativity and original thought.  This research examines both scenarios.  The results indicate that minimum information provided by the professor encourages students to learn more.  However, should the professor decide to provide the students with additional information, such information should be developed by the professor

Flora of Richmond National Battlefield Park, Virginia

An inventory of the vascular flora of nine of eleven units of Richmond National Battlefield Park was compiled from 1985 to 1987. Each site was visited during the growing season in two to four week intervals; plant species were identified and recorded in the field and/or collected for later study. A total of 761 different species were identified in the surveyed units, and 2487 individual records of species per particular park unit were noted. Twenty-three percent of the flora consists of exotic species, largely from Eurasia. Voucher specimens are housed in the herbaria of the University of Richmond and Virginia Commonwealth University

Pest Management Systems to Control Rodents in and around Packing Sheds

Rodent trap types are described and their appropriate placement is indicated

Induced mannosidosis-excretion of oligosaccharides by locoweed-intoxicated sheep

AbstractDaily urine samples were collected from a locoweed-fed sheep, and the oligosaccharide content examined by thin-layer and liquid chromatography. An unusual pattern of urine oligosaccharides was observed, which appears to be characteristic of loco intoxication. Changes in the pattern could be correlated with the onset of visible disease, which occurred approximately 5 weeks after the typical urine sugars were first detected. HPLC showed that these sugars consisted of two homologous series of oligosaccharides containing one and two residues of 2-acetamido-2-deoxy-D-glucose, respectively

OUTCOMES AFTER IMPLANTATION OF BARE-METAL, COVERED AND DRUG-ELUTING STENTS FOR THE TREATMENT OF PULMONARY VEIN STENOSIS IN CHILDREN

Nachrichten aus Frankfurt, Alexander Linneman

Mesoscopic structuring and dynamics of alcohol/water solutions probed by terahertz time-domain spectroscopy and pulsed field gradient nuclear magnetic resonance.

Terahertz and PFG-NMR techniques are used to explore transitions in the structuring of binary alcohol/water mixtures. Three critical alcohol mole fractions (x1, x2, x3) are identified: methanol (10, 30, 70 mol %), ethanol (7, 15, 60 mol %), 1-propanol (2, 10, 50 mol %), and 2-propanol (2, 10, 50 mol %). Above compositions of x1 no isolated alcohol molecules exist, and below x1 the formation of large hydration shells around the hydrophobic moieties of the alcohol is favored. The maximum number of water molecules, N0, in the hydration shell surrounding a single alcohol molecule increases with the length of the carbon chain of the alcohol. At x2 the greatest nonideality of the liquid structure exists with the formation of extended hydrogen bonded networks between alcohol and water molecules. The terahertz data show the maximum absorption relative to that predicted for an ideal mixture at that composition, while the PFG-NMR data exhibit a minimum in the alkyl chain self-diffusivity at x2, showing that the alcohol has reached a minimum in diffusion when this extended alcohol-water network has reached the highest degree of structuring. At x3 an equivalence of the alkyl and alcohol hydroxyl diffusion coefficients is determined by PFG-NMR, suggesting that the molecular mobility of the alcohol molecules becomes independent of that of the water molecules.This is the final published version. It's also available from the Journal of Physical Chemistry B here: http://pubs.acs.org/doi/abs/10.1021/jp502799x

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation

The actin and microtubule cytoskeletons are critically important for cancer cell proliferation, and drugs that target microtubules are widely-used cancer therapies. However, their utility is compromised by toxicities due to dose and exposure. To overcome these issues, we characterized how inhibition of the actin and microtubule cytoskeleton regulatory LIM kinases could be used in drug combinations to increase efficacy. A previously-described LIMK inhibitor (LIMKi) induced dose-dependent microtubule alterations that resulted in significant mitotic defects, and increased the cytotoxic potency of microtubule polymerization inhibitors. By combining LIMKi with 366 compounds from the GSK Published Kinase Inhibitor Set, effective combinations were identified with kinase inhibitors including EGFR, p38 and Raf. These findings encouraged a drug discovery effort that led to development of CRT0105446 and CRT0105950, which potently block LIMK1 and LIMK2 activity in vitro, and inhibit cofilin phosphorylation and increase αTubulin acetylation in cells. CRT0105446 and CRT0105950 were screened against 656 cancer cell lines, and rhabdomyosarcoma, neuroblastoma and kidney cancer cells were identified as significantly sensitive to both LIMK inhibitors. These large-scale screens have identified effective LIMK inhibitor drug combinations and sensitive cancer types. In addition, the LIMK inhibitory compounds CRT0105446 and CRT0105950 will enable further development of LIMK-targeted cancer therapy

Hydro-NEXRAD: An Updated Overview And Metadata Analysis

Hydro-NEXRAD is a prototype system that allows hydrologists to obtain user-specified rainfall data for their research. These data are based on observations collected by the national network of WSR-88D radars, known as NEXRAD. Users interact with Hydro-NEXRAD through a web-based interface that has map-based components for spatial navigation, calendar- and time series plot components for temporal navigation and a menu-based component for selection of processing options. Through the interface, users browse the Hydro-NEXRAD metadata and select data of interest. As the system is approaching the point of being fully operational, the authors and a group of test users have evaluated several aspects of the system. Metadata remains very important for the system functionality. Radar-based, basin-based and point (for selected set of rain gauge locations) metadata serve multiple purposes: 1) enable users to efficiently search for subsets of data (SQL query, visual inspection), 2) provide information on quality of the collected data archive (missing or corrupt data), 3) and have a scientific value (basin-based metadata has a potential to be used as a precipitation input to hydrologic models). The authors provide an updated overview of the Hydro-NEXRAD system. Additionally, the authors present the complete set of Hydro-NEXRAD metadata and discuss their possible applications. © 2008 ASCE