Assessing the performance of the Asian/Pacific islander identification algorithm to infer Hmong ethnicity from electronic health records in California.

OBJECTIVE:This study assesses the performance of the North American Association of Central Cancer Registries Asian/Pacific Islander Identification Algorithm (NAPIIA) to infer Hmong ethnicity. DESIGN AND SETTING:Analyses of electronic health records (EHRs) from 1 January 2011 to 1 October 2015. The NAPIIA was applied to the EHR data, and self-reported Hmong ethnicity from a questionnaire was used as the gold standard. Sensitivity, specificity, positive (PPV) and negative predictive values (NPVs) were calculated comparing the source data ethnicity inferred by the algorithm with the self-reported ethnicity from the questionnaire. PARTICIPANTS:EHRs indicating Hmong, Chinese, Vietnamese and Korean ethnicity who met the original study inclusion criteria were analysed. RESULTS:The NAPIIA had a sensitivity of 78%, a specificity of 99.9%, a PPV of 96% and an NPV of 99%. The prevalence of Hmong population in the sample was 3.9%. CONCLUSION:The high sensitivity of the NAPIIA indicates its effectiveness in detecting Hmong ethnicity. The applicability of the NAPIIA to a multitude of Asian subgroups can advance Asian health disparity research by enabling researchers to disaggregate Asian data and unmask health challenges of different Asian subgroups

Pengaruh Suplementasi Saccharomyces Cerevisiae sebagai Probiotik dalam Ransum Berbasis Pakan Lokal terhadap Performans dan Kecernaan Nutrisi pada Babi Lokal Fase Starter

The long term purposes of the study are to change the mind and the custom of pigs farmers from using restaurant or household wastes to using local feeds enriched with yeast (Saccharomyces cerevisiae). The short term or special purpose of the study are to find out the cheaper alternative feeds for pigs and information of using yeast to improve feeds quality and pigs productivity. The study with those purposes was carried out off farm by supplementing yeast into low quality pig feeds (crude protein/CP ≤ 16%) of local weaned pigs composed of: corn meal, rice brand, soybean/tofu extract and unused fish meal. 12 local weaned pigs were fed 4 treatment diets based on block design of 4 treatments with 3 blocks design procedure. The 4 treatment feeds were formulated as : R0 (commercial diet/551); R1 (basal feed + 2% yeast of daily requirement); R2 (basal feed + 4% yeast of daily requirement); and R3 (basal feed + 6% yeast of daily requirement). Feed intake, daily weight gain, feeds conversion efficiency, protein, and crude fibre digestibility were studied in the study. Statistical analysis showed that the effect of the treatments is not significant (P>0.05) on all variables studied. Supplementation yeast of 6% is the best treatment performing the highest result of most variable studied. The conclusion drawn is that supplementing yeast up to 6% could improve performance of weaned pigs fed low quality feed and perform the similar result with feeding commercial feed (551). It is suggested to use yeast up to 6% in the diet and further research including widen range and high level of yeast supplementation could be done

Telehealth technology: Potentials, challenges and research directions for developing countries

Telehealth has been developed and successfully applied in clinical practices, gained a strong interest and demonstrated its usefulness for medical diagnosis, treatments and rehabilitation worldwide. The advent of high speed communication technology and complex signal processing techniques, and recent advancements in cloud and cognitive computing, has created a new wave of opportunities for delivering remote healthcare applications and services, where the cost-effective diagnosis and treatment solutions as well as healthcare services are important and need to be deployed widely. Nevertheless, there is still a significant challenge in fully adopting this technology due to asymmetry among the healthcare centers, hospitals and the user-ends, especially in developing countries. This paper provides an overview of the telehealth, then to addresses the possible telehealth technologies and applications that could be applied to improve the healthcare service performance, with the focus on the developing countries. The incorporation of different technologies in telehealth including, Internet of Things (IoT), cloud and cognitive computing, medical image processing and effective encoding is introduced and discussed. Finally, the possible research directions, challenges for the efficient telehealth, and potential research and technology collaborations are outlined

Lactobacillus rhamnosus GG enhances intestinal mucus barrier upon Escherichia coli infection

INTRODUCTION: Foodborne infection is a major food safety issue in both developing and developed countries. The use of probiotics has been emerging as a tool for the control of foodborne infections and gastrointestinal disorders such as diarrhea. Our study aims to investigate potential protective effects of probiotics on intestinal epithelial cells against invasion of foodborne pathogens and to elucidate the mechanisms of such effects. We hypothesize that Lactobacillus rhamnosus GG (LGG) can either be used as prevention against or as an antagonist of foodborne pathogens, and such protective effects can be conferred through the upregulation of mucins in the intestinal epithelial cells …postprin

Continuum removal in H\alpha\ extragalactic measurements

We point out an important source of error in measurements of extragalactic H-alpha emission and suggest ways to reduce it. The H-alpha line, used for estimating star formation rates, is commonly measured by imaging in a narrow band and a wide band, both which include the line. The image analysis relies on the accurate removal of the underlying continuum. We discuss in detail the derivation of the emission line's equivalent width and flux for extragalactic extended sources, and the required photometric calibrations. We describe commonly used continuum-subtraction procedures, and discuss the uncertainties that they introduce. Specifically, we analyse errors introduced by colour effects. We show that the errors in the measured H-alpha equivalent width induced by colour effects can lead to underestimates as large as 40% and overestimates as large as 10%, depending on the underlying galaxy's stellar population and the continuum-subtraction procedure used. We also show that these errors may lead to biases in results of surveys, and to the underestimation of the cosmic star formation rate at low redshifts (the low z points in the Madau plot). We suggest a method to significantly reduce these errors using a single colour measurement.Comment: 8 pages, 3 figures, MNRAS in pres

Emission-Line Galaxies from the Hubble Space Telescope Probing Evolution and Reionization Spectroscopically (PEARS) Grism Survey. II: The Complete Sample

We present a full analysis of the Probing Evolution And Reionization Spectroscopically (PEARS) slitess grism spectroscopic data obtained with the Advanced Camera for Surveys on HST. PEARS covers fields within both the Great Observatories Origins Deep Survey (GOODS) North and South fields, making it ideal as a random survey of galaxies, as well as the availability of a wide variety of ancillary observations to support the spectroscopic results. Using the PEARS data we are able to identify star forming galaxies within the redshift volume 0< z<1.5. Star forming regions in the PEARS survey are pinpointed independently of the host galaxy. This method allows us to detect the presence of multiple emission line regions (ELRs) within a single galaxy. 1162 Ha, [OIII] and/or [OII] emission lines have been identified in the PEARS sample of ~906 galaxies down to a limiting flux of ~1e-18 erg/s/cm^2. The ELRs have also been compared to the properties of the host galaxy, including morphology, luminosity, and mass. From this analysis we find three key results: 1) The computed line luminosities show evidence of a flattening in the luminosity function with increasing redshift; 2) The star forming systems show evidence of disturbed morphologies, with star formation occurring predominantly within one effective (half-light) radius. However, the morphologies show no correlation with host stellar mass; and 3) The number density of star forming galaxies with M_* > 1e9} M_sun decreases by an order of magnitude at z<0.5 relative to the number at 0.5<z<0.9 in support of the argument for galaxy downsizing.Comment: Submitted. 48 pages. 19 figures. Accepted to Ap

Stellar Populations of Lyman Break Galaxies at z=1-3 in the HST/WFC3 Early Release Science Observations

We analyze the spectral energy distributions (SEDs) of Lyman break galaxies (LBGs) at z=1-3 selected using the Hubble Space Telescope (HST) Wide Field Camera 3 (WFC3) UVIS channel filters. These HST/WFC3 observations cover about 50 sq. arcmin in the GOODS-South field as a part of the WFC3 Early Release Science program. These LBGs at z=1-3 are selected using dropout selection criteria similar to high redshift LBGs. The deep multi-band photometry in this field is used to identify best-fit SED models, from which we infer the following results: (1) the photometric redshift estimate of these dropout selected LBGs is accurate to within few percent; (2) the UV spectral slope (beta) is redder than at high redshift (z>3), where LBGs are less dusty; (3) on average, LBGs at z=1-3 are massive, dustier and more highly star-forming, compared to LBGs at higher redshifts with similar luminosities (0.1L*<~L<~2.5L*), though their median values are similar within 1-sigma uncertainties. This could imply that identical dropout selection technique, at all redshifts, find physically similar galaxies; and (4) stellar masses of these LBGs are directly proportional to their UV luminosities with a logarithmic slope of ~0.46, and star-formation rates are proportional to their stellar masses with a logarithmic slope of ~0.90. These relations hold true --- within luminosities probed in this study --- for LBGs from z~1.5 to 5. The star-forming galaxies selected using other color-based techniques show similar correlations at z~2, but to avoid any selection biases, and for direct comparison with LBGs at z>3, a true Lyman break selection at z~2 is essential. The future HST UV surveys, both wider and deeper, covering a large luminosity range are important to better understand LBG properties, and their evolution.Comment: Accepted for publication in ApJ (29 pages, 9 figures

Activity and Process Stability of Purified Green Pepper (Capsicum annuum) Pectin Methylesterase

Pectin methylesterase (PME) from green bell peppers (Capsicum annuum) was extracted and purified by affinity chromatography on a CNBr-Sepharose-PMEI column. A single protein peak with pectin methylesterase activity was observed. For the pepper PME, a biochemical characterization in terms of molar mass (MM), isoelectric points (pI), and kinetic parameters for activity and thermostability was performed. The optimum pH for PME activity at 22 °C was 7.5, and its optimum temperature at neutral pH was between 52.5 and 55.0 °C. The purified pepper PME required the presence of 0.13 M NaCl for optimum activity. Isothermal inactivation of purified pepper PME in 20 mM Tris buffer (pH 7.5) could be described by a fractional conversion model for lower temperatures (55?57 °C) and a biphasic model for higher temperatures (58?70 °C). The enzyme showed a stable behavior toward high-pressure/temperature treatments. Keywords: Capsicum annuum; pepper; pectin methylesterase; purification; characterization; thermal and high-pressure stabilit

Feasibility of Using a Commercial Fitness Tracker as an Adjunct to Family-Based Weight Management Treatment: Pilot Randomized Trial.

BACKGROUND: Fitness trackers can engage users through automated self-monitoring of physical activity. Studies evaluating the utility of fitness trackers are limited among adolescents, who are often difficult to engage in weight management treatment and are heavy technology users. OBJECTIVE: We conducted a pilot randomized trial to describe the impact of providing adolescents and caregivers with fitness trackers as an adjunct to treatment in a tertiary care weight management clinic on adolescent fitness tracker satisfaction, fitness tracker utilization patterns, and physical activity levels. METHODS: Adolescents were randomized to 1 of 2 groups (adolescent or dyad) at their initial weight management clinic visit. Adolescents received a fitness tracker and counseling around activity data in addition to standard treatment. A caregiver of adolescents in the dyad group also received a fitness tracker. Satisfaction with the fitness tracker, fitness tracker utilization patterns, and physical activity patterns were evaluated over 3 months. RESULTS: A total of 88 adolescents were enrolled, with 69% (61/88) being female, 36% (32/88) black, 23% (20/88) Hispanic, and 63% (55/88) with severe obesity. Most adolescents reported that the fitness tracker was helping them meet their healthy lifestyle goals (69%) and be more motivated to achieve a healthy weight (66%). Despite this, 68% discontinued use of the fitness tracker by the end of the study. There were no significant differences between the adolescent and the dyad group in outcomes, but adolescents in the dyad group were 12.2 times more likely to discontinue using their fitness tracker if their caregiver also discontinued use of their fitness tracker (95% CI 2.4-61.6). Compared with adolescents who discontinued use of the fitness tracker during the study, adolescents who continued to use the fitness tracker recorded a higher number of daily steps in months 2 and 3 of the study (mean 5760 vs 4148 in month 2, P=.005, and mean 5942 vs 3487 in month 3, P=.002). CONCLUSIONS: Despite high levels of satisfaction with the fitness trackers, fitness tracker discontinuation rates were high, especially among adolescents whose caregivers also discontinued use of their fitness tracker. More studies are needed to determine how to sustain the use of fitness trackers among adolescents with obesity and engage caregivers in adolescent weight management interventions