309 research outputs found
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Can hypnotic suggestibility be measured online?
Hypnosis and hypnotic suggestions are gradually gaining popularity within the consciousness community as established tools for the experimental manipulation of illusions of involuntariness, hallucinations and delusions. However, hypnosis is still far from being a widespread instrument; a crucial hindrance to taking it up is the amount of time needed to invest in identifying people high and low in responsiveness to suggestion. In this study, we introduced an online assessment of hypnotic response and estimated the extent to which the scores and psychometric properties of an online screening differ from an offline one. We propose that the online screening of hypnotic response is viable as it reduces the level of responsiveness only by a slight extent. The application of online screening may prompt researchers to run large-scale studies with more heterogeneous samples, which would help researchers to overcome some of the issues underlying the current replication crisis in psychology
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Computer vs live delivery of the Sussex Waterloo Scale of Hypnotisability (SWASH)
There exist reliable and stable trait differences in the ability to control phenomenology in response to imaginative suggestion. Hypnotisability scales measure response to imaginative suggestion within a hypnotic context. Because hypnotisability has recently been shown to predict measures of experiential change in psychological experiments (e.g., the rubber hand illusion), there is a need for easy to use screening tools which are accessible to researchers with little or no background in hypnosis or imaginative suggestion research. The SWASH is a time efficient group hypnotisability scale which can be administered to up to 50 participants simultaneously. Here we present norms from an undergraduate sample for a recorded version delivered by a computer program alongside norms for a live presentation. Reliability, validity and mean scores are similar across the two presentations. Computer delivery of a prerecorded script provides a simple tool to rapidly screen for hypnotisability in large groups for researchers with no prior experience of hypnosis research
High‐efficiency Al0.22Ga0.78As solar cells grown by molecular beam epitaxy
The quality of pn junction photodetectors made of Al0.2Ga0.8As has been investigated as a first step in the optimization of tandem solar cells. We have obtained 1 sun AM1.5 efficiencies of 16.1% for 0.25 cm2 Al0.22Ga0.78As solar cellsfabricated from molecular beam epitaxy (MBE) material. This efficiency is 3.2 percentage points higher than the previously best reported efficiency of 12.9% for an Al0.2Ga0.8As solar cell fabricated from MBE material
The ‘algebra of evolution’: the Robertson–Price identity and viability selection for body mass in a wild bird population
By the Robertson–Price identity, the change in a quantitative trait owing to
selection, is equal to the trait’s covariance with relative fitness. In this study,
we applied the identity to long-term data on superb fairy-wrens Malurus cyaneus, to estimate phenotypic and genetic change owing to juvenile viability
selection. Mortality in the four-week period between fledging and independence was 40%, and heavier nestlings were more likely to survive, but why?
There was additive genetic variance for both nestling mass and survival, and
a positive phenotypic covariance between the traits, but no evidence of additive genetic covariance. Comparing standardized gradients, the phenotypic
selection gradient was positive, βP = 0.108 (0.036, 0.187 95% CI), whereas the
genetic gradient was not different from zero, βA = −0.025 (−0.19, 0.107 95%
CI). This suggests that factors other than nestling mass were the cause of variation in survival. In particular, there were temporal correlations between mass
and survival both within and between years. We suggest that use of the Price
equation to describe cross-generational change in the wild may be challenging,
but a more modest aim of estimating its first term, the Robertson–Price identity,
to assess within-generation change can provide valuable insights into the
processes shaping phenotypic diversity in natural populations.
This article is part of the theme issue ‘Fifty years of the Price equation’G.K.H. was supported by the U.K. Natural Environment
Research Council (grant no. NE/L002558/1) through the University
of Edinburgh’s E3 Doctoral Training Partnership, and L.E.B.K. was
funded by an ARC Future Fellowship FT110100453. The long-term
superb fairy-wren study research has been facilitated by a series of
Discovery Project grants from the Australian Research Council to
A.C. and L.E.B.K., most recently DP150100298
Time perception and the experience of agency in meditation and hypnosis
Mindfulness meditation and hypnosis are related in opposing ways to awareness of intentions. The cold control theory of hypnosis proposes that hypnotic responding involves the experience of involuntariness while performing an actually intentional action. Hypnosis therefore relies upon inaccurate metacognition about intentional actions and experiences. Mindfulness meditation centrally involves awareness of intentions and is associated with improved metacognitive access to intentions. Therefore, mindfulness meditators and highly hypnotizable people may lie at opposite ends of a spectrum with regard to metacognitive access to intention‐related information. Here we review the theoretical background and evidence for differences in the metacognition of intentions in these groups, as revealed by chronometric measures of the awareness of voluntary action: the timing of an intention to move (Libet's “W” judgments) and the compressed perception of time between an intentional action and its outcome (“intentional binding”). We review these measures and critically evaluate their proposed connection to the experience of volition and sense of agency
Lady Gaga as (dis)simulacrum of monstrosity
Lady Gaga’s celebrity DNA revolves around the notion of monstrosity, an extensively
researched concept in postmodern cultural studies. The analysis that is offered in this
paper is largely informed by Deleuze and Guattari’s notion of monstrosity, as well as
by their approach to the study of sign-systems that was deployed in A Thousand
Plateaus. By drawing on biographical and archival visual data, with a focus on the
relatively underexplored live show, an elucidation is afforded of what is really monstrous
about Lady Gaga. The main argument put forward is that monstrosity as sign
seeks to appropriate the horizon of unlimited semiosis as radical alterity and openness
to signifying possibilities. In this context it is held that Gaga effectively delimits her
unique semioscape; however, any claims to monstrosity are undercut by the inherent
limits of a representationalist approach in sufficiently engulfing this concept. Gaga is
monstrous for her community insofar as she demands of her fans to project their
semiosic horizon onto her as a simulacrum of infinite semiosis. However, this simulacrum
may only be evinced in a feigned manner as a (dis)simulacrum. The analysis of
imagery from seminal live shows during 2011–2012 shows that Gaga’s presumed
monstrosity is more akin to hyperdifferentiation as simultaneous employment of
heterogeneous and potentially dissonant inter pares cultural representations. The article
concludes with a problematisation of audience effects in the light of Gaga’s adoption of
a schematic and post-representationalist strategy in the event of her strategy’s emulation
by competitive artists
Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers
Background: Genome-wide association studies (GWAS) have identified 94 common single-nucleotide polymorphisms (SNPs) associated with breast cancer (BC) risk and 18 associated with ovarian cancer (OC) risk. Several of these are also associated with risk of BC or OC for women who carry a pathogenic mutation in the high-risk BC and OC genes BRCA1 or BRCA2. The combined effects of these variants on BC or OC risk for BRCA1 and BRCA2 mutation carriers have not yet been assessed while their clinical management could benefit from improved personalized risk estimates.
Methods: We constructed polygenic risk scores (PRS) using BC and OC susceptibility SNPs identified through population-based GWAS: for BC (overall, estrogen receptor [ER]-positive, and ER-negative) and for OC. Using data from 15 252 female BRCA1 and 8211 BRCA2 carriers, the association of each PRS with BC or OC risk was evaluated using a weighted cohort approach, with time to diagnosis as the outcome and estimation of the hazard ratios (HRs) per standard deviation increase in the PRS.
Results: The PRS for ER-negative BC displayed the strongest association with BC risk in BRCA1 carriers (HR = 1.27, 95% confidence interval [CI] = 1.23 to 1.31, P = 8.2 x 10(53)). In BRCA2 carriers, the strongest association with BC risk was seen for the overall BC PRS (HR = 1.22, 95% CI = 1.17 to 1.28, P = 7.2 x 10(-20)). The OC PRS was strongly associated with OC risk for both BRCA1 and BRCA2 carriers. These translate to differences in absolute risks (more than 10% in each case) between the top and bottom deciles of the PRS distribution; for example, the OC risk was 6% by age 80 years for BRCA2 carriers at the 10th percentile of the OC PRS compared with 19% risk for those at the 90th percentile of PRS.
Conclusions: BC and OC PRS are predictive of cancer risk in BRCA1 and BRCA2 carriers. Incorporation of the PRS into risk prediction models has promise to better inform decisions on cancer risk management
Illusory temporal binding in meditators
We investigate conditions in which more accurate metacognition may lead to greater susceptibility to illusion; and thus conditions under which mindfulness meditation may lead to less accurate perceptions. Specifically, greater awareness of intentions may lead to an illusory compression of time between a voluntary action and its outcome (“intentional binding”). Here we report that experienced Buddhist mindfulness meditators rather than non-meditators display a greater illusory shift of the timing of an outcome towards an intentional action. Mindfulness meditation involves awareness of causal connections between different mental states, including intentions. We argue that this supports improvements in metacognition targeted at motor intentions. Changes in metacognitive ability may result in an earlier and less veridical experience of the timing of action outcomes either through increased access to sensorimotor pre-representations of an action outcome or by affording greater precision to action timing judgements. Furthermore, as intentional binding is an implicit measure of the sense of agency, these results also provide evidence that mindfulness meditators experience a stronger sense of agency
Behavioral genetics and taste
This review focuses on behavioral genetic studies of sweet, umami, bitter and salt taste responses in mammals. Studies involving mouse inbred strain comparisons and genetic analyses, and their impact on elucidation of taste receptors and transduction mechanisms are discussed. Finally, the effect of genetic variation in taste responsiveness on complex traits such as drug intake is considered. Recent advances in development of genomic resources make behavioral genetics a powerful approach for understanding mechanisms of taste
Carrier thermalization dynamics in single zincblende and wurtzite InP nanowires
Using transient Rayleigh scattering (TRS) measurements, we obtain photoexcited carrier thermalization dynamics for both zincblende (ZB) and wurtzite (WZ) InP single nanowires (NW) with picosecond resolution. A phenomenological fitting model based on direct band-to-band transition theory is developed to extract the electron-hole–plasma density and temperature as a function of time from TRS measurements of single nanowires, which have complex valence band structures. We find that the thermalization dynamics of hot carriers depends strongly on material (GaAs NW vs InP NW) and less strongly on crystal structure (ZB vs WZ). The thermalization dynamics of ZB and WZ InP NWs are similar. But a comparison of the thermalization dynamics in ZB and WZ InP NWs with ZB GaAs NWs reveals more than an order of magnitude slower relaxation for the InP NWs. We interpret these results as reflecting their distinctive phonon band structures that lead to different hot phonon effects. Knowledge of hot carrier thermalization dynamics is an essential component for effective incorporation of nanowire materials into electronic devices
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