Socioeconomic factors and self-reported health outcomes in African Americans with rheumatoid arthritis from the Southeastern United States: The contribution of childhood socioeconomic status

Background: There is abundant evidence that low socioeconomic status (SES) is associated with worse health outcomes among people with Rheumatoid Arthritis (RA); however, the influence of socioeconomic disadvantage in early life has yet to be studied within that population. Methods: Data originated from the cross-sectional arm of the Consortium Evaluation of African-Americans with Rheumatoid Arthritis (CLEAR II), which recruited African-Americans with RA from six sites in the Southeastern United States. We used linear regression models to evaluate associations of parental homeownership status and educational level at participant time of birth with participant-reported fatigue (Visual Analog scale, cm), pain (Visual Analog scale, cm), disability (Health Assessment Questionnaire) and helplessness (Rheumatology Attitudes Index), independently of participant homeownership status and educational level. Models included random effects to account for intra-site correlations, and were adjusted for variables identified using backward selection, from: age, disease-duration, sex, medication use, body-mass index, smoking history. Results: Our sample included 516 CLEAR II participants with full data on demographics and covariates. 89 % of participants were women, the mean age was 54.7 years and mean disease duration was 10.8 years. In age adjusted models, parental non-homeownership was associated with greater fatigue (β = 0.75, 95 % CI = 0.36-1.14), disability (β = 0.12, 95 % CI = 0.04-0.19) and helplessness (β = 0.12, 95 % CI = 0.03-0.21), independently of participant homeownership and education; parental education had a further small influence on self-reported fatigue (β = 0.20, 95 % CI = 0.15-0.24). Conclusions: Parental homeownership, and to a small extent parental education, had modest but meaningful relationships with self-reported health among CLEAR II participants

Women’s responses to changes in U.S. preventive task force’s mammography screening guidelines: results of focus groups with ethnically diverse women

Background: The 2009 U.S. Preventive Services Task Force (USPSTF) changed mammography guidelines to recommend routine biennial screening starting at age 50. This study describes women’s awareness of, attitudes toward, and intention to comply with these new guidelines. Methods: Women ages 40–50 years old were recruited from the Boston area to participate in focus groups (k = 8; n = 77). Groups were segmented by race/ethnicity (Caucasian = 39%; African American = 35%; Latina = 26%), audio-taped, and transcribed. Thematic content analysis was used. Results: Participants were largely unaware of the revised guidelines and suspicious that it was a cost-savings measure by insurers and/or providers. Most did not intend to comply with the change, viewing screening as obligatory. Few felt prepared to participate in shared decision-making or advocate for their preferences with respect to screening. Conclusions: Communication about the rationale for mammography guideline changes has left many women unconvinced about potential disadvantages or limitations of screening. Since further guideline changes are likely to occur with advances in technology and science, it is important to help women become informed consumers of health information and active participants in shared decision-making with providers. Additional research is needed to determine the impact of the USPSTF change on women’s screening behaviors and on breast cancer outcomes

ALMA Observations of SPT-Discovered, Strongly Lensed, Dusty, Star-Forming Galaxies

We present Atacama Large Millimeter/submillimeter Array (ALMA) 860 micrometer imaging of four high-redshift (z=2.8-5.7) dusty sources that were detected using the South Pole Telescope (SPT) at 1.4 mm and are not seen in existing radio to far-infrared catalogs. At 1.5 arcsec resolution, the ALMA data reveal multiple images of each submillimeter source, separated by 1-3 arcsec, consistent with strong lensing by intervening galaxies visible in near-IR imaging of these sources. We describe a gravitational lens modeling procedure that operates on the measured visibilities and incorporates self-calibration-like antenna phase corrections as part of the model optimization, which we use to interpret the source structure. Lens models indicate that SPT0346-52, located at z=5.7, is one of the most luminous and intensely star-forming sources in the universe with a lensing corrected FIR luminosity of 3.7 X 10^13 L_sun and star formation surface density of 4200 M_sun yr^-1 kpc^-2. We find magnification factors of 5 to 22, with lens Einstein radii of 1.1-2.0 arcsec and Einstein enclosed masses of 1.6-7.2x10^11 M_sun. These observations confirm the lensing origin of these objects, allow us to measure the their intrinsic sizes and luminosities, and demonstrate the important role that ALMA will play in the interpretation of lensed submillimeter sources

Analysis of Sunyaev-Zel'dovich effect mass-observable relations using South Pole Telescope observations of an X-ray selected sample of low-mass galaxy clusters and groups

(Abridged) We use 95, 150, and 220GHz observations from the SPT to examine the SZE signatures of a sample of 46 X-ray selected groups and clusters drawn from ~6 deg^2 of the XMM-BCS. These systems extend to redshift z=1.02, have characteristic masses ~3x lower than clusters detected directly in the SPT data and probe the SZE signal to the lowest X-ray luminosities (>10^42 erg s^-1) yet. We develop an analysis tool that combines the SZE information for the full ensemble of X-ray-selected clusters. Using X-ray luminosity as a mass proxy, we extract selection-bias corrected constraints on the SZE significance- and Y_500-mass relations. The SZE significance- mass relation is in good agreement with an extrapolation of the relation obtained from high mass clusters. However, the fit to the Y_500-mass relation at low masses, while in good agreement with the extrapolation from high mass SPT clusters, is in tension at 2.8 sigma with the constraints from the Planck sample. We examine the tension with the Planck relation, discussing sample differences and biases that could contribute. We also present an analysis of the radio galaxy point source population in this ensemble of X-ray selected systems. We find 18 of our systems have 843 MHz SUMSS sources within 2 arcmin of the X-ray centre, and three of these are also detected at significance >4 by SPT. Of these three, two are associated with the group brightest cluster galaxies, and the third is likely an unassociated quasar candidate. We examine the impact of these point sources on our SZE scaling relation analyses and find no evidence of biases. We also examine the impact of dusty galaxies using constraints from the 220 GHz data. The stacked sample provides 2.8$\sigma$ significant evidence of dusty galaxy flux, which would correspond to an average underestimate of the SPT Y_500 signal that is (17+-9) per cent in this sample of low mass systems

ALMA redshifts of millimeter-selected galaxies from the SPT survey: The redshift distribution of dusty star-forming galaxies

Using the Atacama Large Millimeter/submillimeter Array (ALMA), we have conducted a blind redshift survey in the 3 mm atmospheric transmission window for 26 strongly lensd dusty star-forming galaxies (DSFGs) selected with the South Pole Telescope (SPT). The sources were selected to have S_1.4mm>20 mJy and a dust-like spectrum and, to remove low-z sources, not have bright radio (S_843MHz<6mJy) or far-infrared counterparts (S_100um<1 Jy, S_60um<200mJy). We robustly detect 44 line features in our survey, which we identify as redshifted emission lines of 12CO, 13CO, [CI], H2O, and H2O+. We find one or more spectral features in 23 sources yielding a ~90% detection rate for this survey; in 12 of these sources we detect multiple lines, while in 11 sources we detect only a single line. For the sources with only one detected line, we break the redshift degeneracy with additional spectroscopic observations if available, or infer the most likely line identification based on photometric data. This yields secure redshifts for ~70% of the sample. The three sources with no lines detected are tentatively placed in the redshift desert between 1.7<z<2.0. The resulting mean redshift of our sample is =3.5. This finding is in contrast to the redshift distribution of radio-identified DSFGs, which have a significantly lower mean redshift of =2.3 and for which only 10-15% of the population is expected to be at z>3. We discuss the effect of gravitational lensing on the redshift distribution and compare our measured redshift distribution to that of models in the literature

ALMA redshifts of millimeter-selected galaxies from the SPT survey: The redshift distribution of dusty star-forming galaxies

Using the Atacama Large Millimeter/submillimeter Array (ALMA), we have conducted a blind redshift survey in the 3 mm atmospheric transmission window for 26 strongly lensd dusty star-forming galaxies (DSFGs) selected with the South Pole Telescope (SPT). The sources were selected to have S_1.4mm&gt;20 mJy and a dust-like spectrum and, to remove low-z sources, not have bright radio (S_843MHz&lt;6mJy) or far-infrared counterparts (S_100um&lt;1 Jy, S_60um&lt;200mJy). We robustly detect 44 line features in our survey, which we identify as redshifted emission lines of 12CO, 13CO, [CI], H2O, and H2O+. We find one or more spectral features in 23 sources yielding a ~90% detection rate for this survey; in 12 of these sources we detect multiple lines, while in 11 sources we detect only a single line. For the sources with only one detected line, we break the redshift degeneracy with additional spectroscopic observations if available, or infer the most likely line identification based on photometric data. This yields secure redshifts for ~70% of the sample. The three sources with no lines detected are tentatively placed in the redshift desert between 1.7=3.5. This finding is in contrast to the redshift distribution of radio-identified DSFGs, which have a significantly lower mean redshift of =2.3 and for which only 10-15% of the population is expected to be at z&gt;3. We discuss the effect of gravitational lensing on the redshift distribution and compare our measured redshift distribution to that of models in the literature.</z<2.0.

Submillimeter Observations of Millimeter Bright Galaxies Discovered by the South Pole Telescope

We present APEX SABOCA 350micron and LABOCA 870micron observations of 11 representative examples of the rare, extremely bright (S_1.4mm > 15mJy), dust-dominated millimeter-selected galaxies recently discovered by the South Pole Telescope (SPT). All 11 sources are robustly detected with LABOCA with 40 < S_870micron < 130mJy, approximately an order of magnitude higher than the canonical submillimeter galaxy (SMG) population. Six of the sources are also detected by SABOCA at >3sigma, with the detections or upper limits providing a key constraint on the shape of the spectral energy distribution (SED) near its peak. We model the SEDs of these galaxies using a simple modified blackbody and perform the same analysis on samples of SMGs of known redshift from the literature. These calibration samples inform the distribution of dust temperature for similar SMG populations, and this dust temperature prior allows us to derive photometric redshift estimates and far infrared luminosities for the sources. We find a median redshift of = 3.0, higher than the = 2.2 inferred for the normal SMG population. We also derive the apparent size of the sources from the temperature and apparent luminosity, finding them to appear larger than our unlensed calibration sample, which supports the idea that these sources are gravitationally magnified by massive structures along the line of sight

GALAXY CLUSTERS DISCOVERED VIA THE SUNYAEV-ZEL'DOVICH EFFECT IN THE 2500-SQUARE-DEGREE SPT-SZ SURVEY

We present a catalog of galaxy clusters selected via their Sunyaev-Zel'dovich (SZ) effect signature from 2500 deg$^2$ of South Pole Telescope (SPT) data. This work represents the complete sample of clusters detected at high significance in the 2500-square-degree SPT-SZ survey, which was completed in 2011. A total of 677 (409) cluster candidates are identified above a signal-to-noise threshold of $\xi$ =4.5 (5.0). Ground- and space-based optical and near-infrared (NIR) imaging confirms overdensities of similarly colored galaxies in the direction of 516 (or 76%) of the $\xi$>4.5 candidates and 387 (or 95%) of the $\xi$>5 candidates; the measured purity is consistent with expectations from simulations. Of these confirmed clusters, 415 were first identified in SPT data, including 251 new discoveries reported in this work. We estimate photometric redshifts for all candidates with identified optical and/or NIR counterparts; we additionally report redshifts derived from spectroscopic observations for 141 of these systems. The mass threshold of the catalog is roughly independent of redshift above $z$~0.25 leading to a sample of massive clusters that extends to high redshift. The median mass of the sample is $M_{\scriptsize 500c}(\rho_\mathrm{crit})$ ~ 3.5 x 10$^{14} M_\odot h^{-1}$, the median redshift is $z_{med}$ =0.55, and the highest-redshift systems are at $z$>1.4. The combination of large redshift extent, clean selection, and high typical mass makes this cluster sample of particular interest for cosmological analyses and studies of cluster formation and evolution

Constraints on the CMB temperature evolution using multiband measurements of the Sunyaev-Zel'dovich effect with the South Pole Telescope

The adiabatic evolution of the temperature of the cosmic microwave background (CMB) is a key prediction of standard cosmology. We study deviations from the expected adiabatic evolution of the CMB temperature of the form $T(z) =T_0(1+z)^{1-\alpha}$ using measurements of the spectrum of the Sunyaev Zel'dovich Effect with the South Pole Telescope (SPT). We present a method for using the ratio of the Sunyaev Zel'dovich signal measured at 95 and 150 GHz in the SPT data to constrain the temperature of the CMB. We demonstrate that this approach provides unbiased results using mock observations of clusters from a new set of hydrodynamical simulations. We apply this method to a sample of 158 SPT-selected clusters, spanning the redshift range $0.05 < z < 1.35$, and measure $\alpha = 0.017^{+0.030}_{-0.028}$, consistent with the standard model prediction of $\alpha=0$. In combination with other published results, we constrain $\alpha = 0.011 \pm 0.016$, an improvement of $\sim 20\%$ over published constraints. This measurement also provides a strong constraint on the effective equation of state in models of decaying dark energy $w_\mathrm{eff} = -0.987^{+0.016}_{-0.017}$