91 research outputs found

    Augmented Tikhonov Regularization Method for Dynamic Load Identification

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    We introduce the augmented Tikhonov regularization method motivated by Bayesian principle to improve the load identification accuracy in seriously ill-posed problems. Firstly, the Green kernel function of a structural dynamic response is established; then, the unknown external loads are identified. In order to reduce the identification error, the augmented Tikhonov regularization method is combined with the Green kernel function. It should be also noted that we propose a novel algorithm to determine the initial values of the regularization parameters. The initial value is selected by finding a local minimum value of the slope of the residual norm. To verify the effectiveness and the accuracy of the proposed method, three experiments are performed, and then the proposed algorithm is used to reproduce the experimental results numerically. Numerical comparisons with the standard Tikhonov regularization method show the advantages of the proposed method. Furthermore, the presented results show clear advantages when dealing with ill-posedness of the problem

    Configuring Intelligent Reflecting Surface with Performance Guarantees: Blind Beamforming

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    This work gives a blind beamforming strategy for intelligent reflecting surface (IRS), aiming to boost the received signal-to-noise ratio (SNR) by coordinating phase shifts across reflective elements in the absence of channel information. While the existing methods of IRS beamforming typically first estimate channels and then optimize phase shifts, we propose a conditional sample mean based statistical approach that explores the wireless environment via random sampling without performing any channel estimation. Remarkably, the new method just requires a polynomial number of random samples to yield an SNR boost that is quadratic in the number of reflective elements, whereas the standard random-max sampling algorithm can only achieve a linear boost under the same condition. Moreover, we gain additional insight into blind beamforming by interpreting it as a least squares problem. Field tests demonstrate the significant advantages of the proposed blind beamforming algorithm over the benchmark algorithms in enhancing wireless transmission.Comment: 16 pages, 15 figure

    A Linear Time Algorithm for the Optimal Discrete IRS Beamforming

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    It remains an open problem to find the optimal configuration of phase shifts under the discrete constraint for intelligent reflecting surface (IRS) in polynomial time. The above problem is widely believed to be difficult because it is not linked to any known combinatorial problems that can be solved efficiently. The branch-and-bound algorithms and the approximation algorithms constitute the best results in this area. Nevertheless, this work shows that the global optimum can actually be reached in linear time in terms of the number of reflective elements (REs) of IRS. The main idea is to geometrically interpret the discrete beamforming problem as choosing the optimal point on the unit circle. Although the number of possible combinations of phase shifts grows exponentially with the number of REs, it turns out that there are merely a linear number of points on the unit circle to consider. Furthermore, the proposed algorithm can be viewed as a novel approach to a special case of the discrete quadratic program (QP).Comment: 5 page

    RIS-Based On-the-Air Semantic Communications -- a Diffractional Deep Neural Network Approach

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    Semantic communication has gained significant attention recently due to its advantages in achieving higher transmission efficiency by focusing on semantic information instead of bit-level information. However, current AI-based semantic communication methods require digital hardware for implementation. With the rapid advancement on reconfigurable intelligence surfaces (RISs), a new approach called on-the-air diffractional deep neural networks (D2^2NN) can be utilized to enable semantic communications on the wave domain. This paper proposes a new paradigm of RIS-based on-the-air semantic communications, where the computational process occurs inherently as wireless signals pass through RISs. We present the system model and discuss the data and control flows of this scheme, followed by a performance analysis using image transmission as an example. In comparison to traditional hardware-based approaches, RIS-based semantic communications offer appealing features, such as light-speed computation, low computational power requirements, and the ability to handle multiple tasks simultaneously.Comment: 17 pages, 5 figures, accepted by IEEE WC

    Are you always ignoring attitude-challenging messages? Eye-tracking selective exposure on Chinese’ lowly involved news consumption

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    This study employs a pre-post-test design to investigate the selective exposure behaviors while consuming news with low involvement. The experiment incorporates eye-tracking and self-report measures to explore participants’ preferences for attitude-consistent and attitude-inconsistent information. The results of the study indicate that attitude consistency does not serve as the primary determinant of selective exposure; instead, participants demonstrate a stronger inclination towards engaging with a smaller number of posts from a particular perspective. Following their exposure to the news feed, participants display a heightened tendency to read articles with neutral attitudes. In addition, individuals who initially held a particular attitude tend to shift towards a neutral standpoint, particularly when exposed to a mostly-consistent opinion climate. Notably, participants’ attitudes do not tend to become radicalized under any opinion climate. The study acknowledges its limitations and proceeds to discuss the implications of these findings

    Pivotal Role of Dogs in Rabies Transmission, China

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    The number of dog-mediated rabies cases in China has increased exponentially; the number of human deaths has been high, primarily in poor, rural communities. We review the incidence of rabies in China based on data from 1950 and 2004, obtained mainly from epidemiologic bulletins published by the Chinese Ministry of Health

    Pooled Sequencing Analysis of Geese (Anser cygnoides) Reveals Genomic Variations Associated With Feather Color

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    During the domestication of the goose a change in its feather color took place, however, the molecular mechanisms responsible for this change are not completely understood. Here, we performed whole-genome resequencing on three pooled samples of geese (feral and domestic geese), with two distinct feather colors, to identify genes that might regulate feather color. We identified around 8 million SNPs within each of the three pools and validated allele frequencies for a subset of these SNPs using PCR and Sanger sequencing. Several genomic regions with signatures of differential selection were found when we compared the gray and white feather color populations using the FST and Hp approaches. When we combined previous functional studies with our genomic analyses we identified 26 genes (KITLG, MITF, TYRO3, KIT, AP3B1, SMARCA2, ROR2, CSNK1G3, CCDC112, VAMP7, SLC16A2, LOC106047519, RLIM, KIAA2022, ST8SIA4, LOC106044163, TRPM6, TICAM2, LOC106038556, LOC106038575, LOC106038574, LOC106038594, LOC106038573, LOC106038604, LOC106047489, and LOC106047492) that potentially regulate feather color in geese. These results substantially expand the catalog of potential feather color regulators in geese and provide a basis for further studies on domestication and avian feather coloration

    Association of thyroid-stimulating hormone and lipid levels with suicide attempts among adolescents with major depressive disorder in China

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    ObjectivesEvidence suggested that thyroid-stimulating hormone (TSH) and lipid levels were associated with major depressive disorder (MDD). However, its role in suicide attempts in adolescents with MDD was unclear. This investigation was to probe into the relationship between TSH, lipid levels, and attempted suicide in adolescents with MDD.MethodsA total of 179 adolescents with MDD were included from January 2021 to January 2022. Socio-demographic data and clinical data were obtained through self-made questionnaires. TSH and lipid levels were analyzed by a recognized laboratory. The Epidemiological Studies Depression Scale (CES-D) was used to assess the severity of depression. Questions about whether there was a behavior of suicide attempts were completed through conversation interviews.ResultsResults showed that the CES-D total score, TSH, and low-density lipoprotein cholesterol (LDL-C) of suicide attempters were significantly higher than those of non-suicide attempters. Ordinary family relationships were more likely to attempt suicide than good family relationships. The CES-D total score, ordinary family relationships, TSH and LDL-C were still significant in binary logistic regression, with an adjusted odds ratio (OR) of 1.04, 3.42, 5.14, and 1.76, respectively. The area under the receiver operating characteristic (ROC) curve showed that the area under the ROC curve (AUC) ranged from 0.60 to 0.74.ConclusionSuicide attempts are common among adolescents with MDD and were associated with CES-D total score, ordinary family relationships, TSH, and LDL-C. Given the association between suicide attempts and TSH and LDL-C, the dynamic changes in TSH and LDL-C levels should be detected regularly

    雷公藤红素通过靶向核受体Nur77促进损伤线粒体自噬而抑制炎症反应

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    文章简介线粒体在细胞死亡、自噬、免疫和炎症中起着不可或缺的作用。前期研究发现,孤儿核受体Nur77通过靶向线粒体诱导细胞凋亡。本文报道了Nur77作为具有抗炎作用的雷公藤红素的直接靶点,介导雷公藤红素通过自噬清除损伤线粒体,抑制炎症反应而达到治疗炎症疾病包括肥胖症的功能。研究人员发现,雷公藤红素的结合
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