Method for Extracting the Glueball Wave Function

We describe a nonperturbative method for calculating the QCD vacuum and glueball wave functions, based on an eigenvalue equation approach to Hamiltonian lattice gauge theory. Therefore, one can obtain more physical information than the conventional simulation methods. For simplicity, we take the 2+1 dimensional U(1) model as an example. The generalization of this method to 3+1 dimensional QCD is straightforward.Comment: 3 pages, Latex. Presented at Lattice 97: 15th International Symposium on Lattice Field Theory, Edinburgh, Scotland, 22-26 Jul 1997, to appear in Nucl. Phys. B(Proc. Suppl.

Effect of Zhen-wu decoction on chronic heart failure in rats

Purpose: To investigate the effect of Zhen-wu decoction (ZWD) on oxidative stress and hemodynamics in chronic congestive heart failure (CHF) rats.Methods: After Sprague Dawley (SD) rats were successfully prepared into CHF, they were randomly divided into normal control group, model (untreated CHF) group,  captopril group, high-dose, middledose and low-dose of ZWD groups, and were  treated with drugs for 4 weeks respectively. At the end of the experiment,  hemodynamic function, whole heart weight index, blood creatinine kinase (CK), superoxide dismutase (SOD), malondialdehyde (MDA), nitric oxide (NO) and nitric oxide synthase (NOS) were determined.Results: Compared with normal control group, ZWD group showed decreased arterial systolic pressure (SBP, 89.16 ± 17.27 mmHg), diastolic pressure (DBP, 72.54 ± 22.36 mmHg), mean arterial pressure (MAP, 72.64 ± 11.87 mmHg), heart rate (HR, 368.25 ± 39.12 beats/min), left ventricular systolic peak (LVSP, 105.27 ± 15.23 mmHg), and left ventricular pressure change rate (dp/dt max) (p < 0.05), while left ventricular end diastolic pressure (LVEDP) (19.52 ± 1.89 mmHg), whole heart weight index (2.74 ± 0.16 mg/g), blood CK (0.98 ± 0.16 U/mL), MDA (17.28 ± 2.94 nmol/mL), NO (36.35 ± 3.27 umol/L), NOS (39.89 ± 3.56 U/mL) significantly  increased (p < 0.05). High dose of ZWD significantly improved hemodynamic  function, lowered MDA (8.85 ± 2.14 nmol/mL) and NO (24.25 ± 3.21 umol/L) levels (p < 0.05), and also decreased CK (0.58 ± 0.37 U/mL) and NOS (26.12 ± 3.87 U/mL) in CHF rats (p < 0.05).Conclusion: ZWD improves adriamycin-induced chronic congestive heart failure in rats significantly, and therefore has potential to be developed for the management of chronic congestive heart failure.Keywords: Zhen-wu decoction, Chronic heart failure, Hemodynamic function,  Oxidative stres

Compensation effect in carbon nanotube quantum dots coupled to polarized electrodes in the presence of spin-orbit coupling

We study theoretically the Kondo effect in carbon nanotube quantum dot attached to polarized electrodes. Since both spin and orbit degrees of freedom are involved in such a system, the electrode polarization contains the spin- and orbit-polarizations as well as the Kramers polarization in the presence of the spin-orbit coupling. In this paper we focus on the compensation effect of the effective fields induced by different polarizations by applying magnetic field. The main results are i) while the effective fields induced by the spin- and orbit-polarizations remove the degeneracy in the Kondo effect, the effective field induced by the Kramers polarization enhances the degeneracy through suppressing the spin-orbit coupling; ii) while the effective field induced by the spin-polarization can not be compensated by applying magnetic field, the effective field induced by the orbit-polarization can be compensated; and iii) the presence of the spin-orbit coupling does not change the compensation behavior observed in the case without the spin-orbit coupling. These results are observable in an ultraclean carbon-nanotube quantum dot attached to ferromagnetic contacts under a parallel applied magnetic field along the tube axis and it would deepen our understanding on the Kondo physics of the carbon nanotube quantum dot.Comment: 8 pages, 6 figure

Correlation between diabetic retinopathy and diabetic nephropathy: a two-sample Mendelian randomization study

Rationale & objectiveA causal relationship concerning diabetic retinopathy (DR) and diabetic nephropathy (DN) has been studied in many epidemiological observational studies. We conducted a two-sample mendelian randomization study from the perspective of genetics to assess these associations.Methods20 independent single nucleotide polymorphisms (SNPs) associated with diabetic retinopathy were selected from the FinnGen consortium. Summary-level data for diabetic nephropathy were obtained from the publicly available genome-wide association studies (GWAS) database, FinnGen and CKDGen consortium. Inverse variance weighted (IVW) was selected as the primary analysis. MR-Egger, weighted median (WM), simple mode and weighted mode were used as complementary methods to examine causality. Additionally, sensitivity analyses including Cochran’s Q test, MR-Egger, MR-Pleiotropy Residual Sum and Outlier (MR-PRESSO), and leave-one-out analyses were conducted to guarantee the accuracy and robustness of our MR analysis.ResultsOur current study demonstrated positive associations of genetically predicted diabetic retinopathy with diabetic nephropathy (OR=1.32; P=3.72E-11), type 1 diabetes with renal complications (OR=1.96; P= 7.11E-11), and type 2 diabetes with renal complications (OR=1.26, P=3.58E-04). Further subtype analysis and multivariate mendelian randomization (MVMR) also reached the same conclusion. A significant casualty with DN was demonstrated both in non-proliferative DR (OR=1.07, P=0.000396) and proliferative DR (OR=1.67, P=3.699068E-14). All the findings were robust across several sensitivity analyses.ConclusionConsistent with previous clinical studies, our findings revealed a positive correlation between DR and DN, providing genetic evidence for the non-invasive nature of DR in predicting DN