Odin observations of ammonia in the Sgr A +50 km/s Cloud and Circumnuclear Disk

Context. The Odin satellite is now into its sixteenth year of operation, much surpassing its design life of two years. One of the sources which Odin has observed in great detail is the Sgr A Complex in the centre of the Milky Way. Aims. To study the presence of NH3 in the Galactic Centre and spiral arms. Methods. Recently, Odin has made complementary observations of the 572 GHz NH3 line towards the Sgr A +50 km/s Cloud and Circumnuclear Disk (CND). Results. Significant NH3 emission has been observed in both the +50 km/s Cloud and the CND. Clear NH3 absorption has also been detected in many of the spiral arm features along the line of sight from the Sun to the core of our Galaxy. Conclusions. The very large velocity width (80 km/s) of the NH3 emission associated with the shock region in the southwestern part of the CND may suggest a formation/desorption scenario similar to that of gas-phase H2O in shocks/outflows.Comment: 5 pages, 3 figures, 3 table

Overregulation of Health Care: Musings on Disruptive Innovation Theory

Disruptive innovation theory provides one lens through which to describe how regulations may stifle innovation and increase costs. Basing their discussion on this theory, Curtis and Schulman consider some of the effects that regulatory controls may have on innovation in the health sector

Impurity-induced dephasing of Andreev states

A study is presented concerning the influence of flicker noise in the junction transparency on coherent transport in Andreev states. The amount of dephasing is estimated for a microwave-activated quantum interferometer. Possibilities of experimentally investigating the coupling between a superconducting quantum point contact and its electromagnetic environment are discussed.Comment: 8 pages, 4 figure

The RHIC Zero Degree Calorimeter

High Energy collisions of nuclei usually lead to the emission of evaporation neutrons from both ``beam'' and ``target'' nuclei. At the RHIC heavy ion collider with 100GeV/u beam energy, evaporation neutrons diverge by less than $~2$ milliradians from the beam axis Neutral beam fragments can be detected downstream of RHIC ion collisions (and a large aperture Accelerator dipole magnet) if $\theta\leq$ 4 mr but charged fragments in the same angular range are usually too close to the beam trajectory. In this 'zero degree' region produced particles and other secondaries deposit negligible energy when compared with that of beam fragmentation neutrons. The purpose of the RHIC zero degree calorimeters (ZDC's) is to detect neutrons emitted within this cone along both beam directions and measure their total energy (from which we calculate multiplicity). The ZDC coincidence of the 2 beam directions is a minimal bias selection of heavy ion collisions. This makes it useful as an event trigger and a luminosity monitor\cite{baltz} and for this reason we built identical detectors for all 4 RHIC experiments. The neutron multiplicity is also known to be correlated with event geometry \cite{appel} and will be used to measure collision centrality in mutual beam int eractions.Comment: 18 pages, 12 figure

Geometric phases of scattering states in a ring geometry: adiabatic pumping in mesoscopic devices

Geometric phases of scattering states in a ring geometry are studied based on a variant of the adiabatic theorem. Three time scales, i.e., the adiabatic period, the system time and the dwell time, associated with adiabatic scattering in a ring geometry plays a crucial role in determining geometric phases, in contrast to only two time scales, i.e., the adiabatic period and the dwell time, in an open system. We derive a formula connecting the gauge invariant geometric phases acquired by time-reversed scattering states and the circulating (pumping) current. A numerical calculation shows that the effect of the geometric phases is observable in a nanoscale electronic device.Comment: 9 pages, 3 figure

Implementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review.

Background: Antibiotics are the most common medicines prescribed to children in hospitals and the community, with a high proportion of potentially inappropriate use. Antibiotic misuse increases the risk of toxicity, raises healthcare costs, and selection of resistance. The primary aim of this systematic review is to summarize the current state of evidence of the implementation and outcomes of pediatric antimicrobial stewardship programs (ASPs) globally. Methods: MEDLINE, Embase and Cochrane Library databases were systematically searched to identify studies reporting on ASP in children aged 0-18 years and conducted in outpatient or in-hospital settings. Three investigators independently reviewed identified articles for inclusion and extracted relevant data. Results: Of the 41,916 studies screened, 113 were eligible for inclusion in this study. Most of the studies originated in the USA (52.2%), while a minority were conducted in Europe (24.7%) or Asia (17.7%). Seventy-four (65.5%) studies used a before-and-after design, and sixteen (14.1%) were randomized trials. The majority (81.4%) described in-hospital ASPs with half of interventions in mixed pediatric wards and ten (8.8%) in emergency departments. Only sixteen (14.1%) studies focused on the costs of ASPs. Almost all the studies (79.6%) showed a significant reduction in inappropriate prescriptions. Compliance after ASP implementation increased. Sixteen of the included studies quantified cost savings related to the intervention with most of the decreases due to lower rates of drug administration. Seven studies showed an increased susceptibility of the bacteria analysed with a decrease in extended spectrum beta-lactamase producers E. coli and K. pneumoniae; a reduction in the rate of P. aeruginosa carbapenem resistance subsequent to an observed reduction in the rate of antimicrobial days of therapy; and, in two studies set in outpatient setting, an increase in erythromycin-sensitive S. pyogenes following a reduction in the use of macrolides. Conclusions: Pediatric ASPs have a significant impact on the reduction of targeted and empiric antibiotic use, healthcare costs, and antimicrobial resistance in both inpatient and outpatient settings. Pediatric ASPs are now widely implemented in the USA, but considerable further adaptation is required to facilitate their uptake in Europe, Asia, Latin America and Africa

Circularly polarized waves in a plasma with vacuum polarization effects

The theory for large amplitude circularly polarized waves propagating along an external magnetic field is extended in order to include also vacuum polarization effects. A general dispersion relation, which unites previous results, is derived.Comment: 5 pages (To appear in Physics of Plasmas

Poisson equation and self-consistent periodical Anderson model

We show that the formally exact expression for the free energy (with a non-relativistic Hamiltonian) for the correlated metal generates the Poisson equation within the saddle-point approximation for the electric potential, where the charge density automatically includes correlations. In this approximation the problem is reduced to the self-consistent periodical Anderson model (SCPAM). The parameter of the mixing interaction in this formulation have to be found self-consistently together with the correlated charge density. The factors, calculated by Irkhin, for the mixing interaction, which reflect the structure of the many-electron states of the \f-ion involved, arise automatically in this formulation and are quite sensitive to the specific element we are interested in. We also discuss the definitions of the mixing interaction for the mapping from ab initio to model calculations.Comment: 25 pages, no figure