1,138 research outputs found
PISA as a political instrument: one history behind the formulating of the PISA programme
El objetivo principal de este artículo es el análisis histórico que se halla en el desarrollo de las
evaluaciones internacionales como mecanismo de gobernación.
Así, el autor analiza el contexto económico y político que ha servido de base para las evaluaciones
internacionales en general y PISA en particular. Se describe la génesis de la evaluación educativa
desde el siglo XIX hasta las primeras décadas del siglo XX como un primer hito en el desarrollo de
la evaluación educativa, una vez establecida la idea de la evaluación como base para las reformas
educativas y cada vez más ligada a las posiciones sociales y salarios.The main focus of his historical analysis is on the development of international assessment as a
device for political governing.Thus, the autor analyses the economic and political context which formed the background for
international assessment in general and PISA in particular. It traces the genesis of educational
assessment back to the 19th century and identifies the early decades of the 20th century as a first
milestone in the development of educational assessment, when the idea of the evaluation as a
base for educational reforms was established and educational assessment was increasingly linked
to social positions and salaries.Grupo FORCE (HUM-386). Departamento de Didáctica y Organización Escolar de la Universidad de Granada
Anomalous diffusion as a signature of collapsing phase in two dimensional self-gravitating systems
A two dimensional self-gravitating Hamiltonian model made by
fully-coupled classical particles exhibits a transition from a collapsing phase
(CP) at low energy to a homogeneous phase (HP) at high energy. From a dynamical
point of view, the two phases are characterized by two distinct single-particle
motions : namely, superdiffusive in the CP and ballistic in the HP. Anomalous
diffusion is observed up to a time that increases linearly with .
Therefore, the finite particle number acts like a white noise source for the
system, inhibiting anomalous transport at longer times.Comment: 10 pages, Revtex - 3 Figs - Submitted to Physical Review
Patient engagement with antibiotic messaging in secondary care: a qualitative feasibility study of the ‘review & revise’ experience
Background: We aimed to investigate and optimise the acceptability and usefulness of a patient leaflet about antibiotic prescribing decisions made during hospitalisation, and to explore individual patient experiences and preferences regarding the process of antibiotic prescription ‘review & revise’ which is a key strategy to minimise antibiotic overuse in hospitals.
Methods: In this qualitative study, run within the feasibility study of a large, cluster-randomised stepped wedge trial of 36 hospital organisations, a series of semi-structured, think-aloud telephone interviews were conducted and data were analysed using thematic analysis. Fifteen adult patients who had experienced a recent acute medical hospital admission during which they had been prescribed antimicrobials and offered a patient leaflet about antibiotic prescribing were recruited to the study.
Results: Participants reacted positively to the leaflet, reporting that it was both an accessible and important source of information which struck the appropriate balance between informing and reassuring. Participants all valued open communication with clinicians, and were keen to be involved in antibiotic prescribing decisions, with individuals reporting positive experiences regarding antibiotic prescription changes or stopping. Many participants had prior experience or knowledge of antibiotics and resistance, and generally welcomed efforts to reduce antibiotic usage. Overall, there was a feeling that healthcare professionals (HCPs) are trusted experts providing the most appropriate treatment for individual patient conditions.
Conclusions: This study offers novel insights into how patients within secondary care are likely to respond to messages advocating a reduction in the use of antibiotics through the ‘review & revise’ approach. Due to the level of trust that patients place in their care provider, encouraging HCPs within secondary care to engage patients with greater communication and information provision could provide great advantages in the drive to reduce antibiotic use. It may also be beneficial for HCPs to view patient experiences as cumulative events that have the potential to impact future behaviour around antibiotic use. Finally, pre-testing messages about antibiotic prescribing and resistance is vital to dispelling any misconceptions either around effectiveness of treatment for patients, or perceptions of how messages may be received
Interleukin-2 therapy in patients with HIV infection
BACKGROUND
Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone. The clinical implication of these increases is not known.
METHODS
We conducted two trials: the Subcutaneous Recombinant, Human Interleukin-2 in HIV-Infected Patients with Low CD4+ Counts under Active Antiretroviral Therapy (SILCAAT) study and the Evaluation of Subcutaneous Proleukin in a Randomized International Trial (ESPRIT). In each, patients infected with the human immunodeficiency virus (HIV) who had CD4+ cell counts of either 50 to 299 per cubic millimeter (SILCAAT) or 300 or more per cubic millimeter (ESPRIT) were randomly assigned to receive interleukin-2 plus antiretroviral therapy or antiretroviral therapy alone. The interleukin-2 regimen consisted of cycles of 5 consecutive days each, administered at 8-week intervals. The SILCAAT study involved six cycles and a dose of 4.5 million IU of interleukin-2 twice daily; ESPRIT involved three cycles and a dose of 7.5 million IU twice daily. Additional cycles were recommended to maintain the CD4+ cell count above predefined target levels. The primary end point of both studies was opportunistic disease or death from any cause.
RESULTS
In the SILCAAT study, 1695 patients (849 receiving interleukin-2 plus antiretroviral therapy and 846 receiving antiretroviral therapy alone) who had a median CD4+ cell count of 202 cells per cubic millimeter were enrolled; in ESPRIT, 4111 patients (2071 receiving interleukin-2 plus antiretroviral therapy and 2040 receiving antiretroviral therapy alone) who had a median CD4+ cell count of 457 cells per cubic millimeter were enrolled. Over a median follow-up period of 7 to 8 years, the CD4+ cell count was higher in the interleukin-2 group than in the group receiving antiretroviral therapy alone--by 53 and 159 cells per cubic millimeter, on average, in the SILCAAT study and ESPRIT, respectively. Hazard ratios for opportunistic disease or death from any cause with interleukin-2 plus antiretroviral therapy (vs. antiretroviral therapy alone) were 0.91 (95% confidence interval [CI], 0.70 to 1.18; P=0.47) in the SILCAAT study and 0.94 (95% CI, 0.75 to 1.16; P=0.55) in ESPRIT. The hazard ratios for death from any cause and for grade 4 clinical events were 1.06 (P=0.73) and 1.10 (P=0.35), respectively, in the SILCAAT study and 0.90 (P=0.42) and 1.23 (P=0.003), respectively, in ESPRIT.
CONCLUSIONS
Despite a substantial and sustained increase in the CD4+ cell count, as compared with antiretroviral therapy alone, interleukin-2 plus antiretroviral therapy yielded no clinical benefit in either study. (ClinicalTrials.gov numbers, NCT00004978 [ESPRIT] and NCT00013611 [SILCAAT study].
Aging in a Two-Dimensional Ising Model with Dipolar Interactions
Aging in a two-dimensional Ising spin model with both ferromagnetic exchange
and antiferromagnetic dipolar interactions is established and investigated via
Monte Carlo simulations. The behaviour of the autocorrelation function
is analyzed for different values of the temperature, the waiting
time and the quotient , and being the
strength of exchange and dipolar interactions respectively. Different
behaviours are encountered for at low temperatures as is
varied. Our results show that, depending on the value of , the dynamics
of this non-disordered model is consistent either with a slow domain dynamics
characteristic of ferromagnets or with an activated scenario, like that
proposed for spin glasses.Comment: 4 pages, RevTex, 5 postscript figures; acknowledgment added and some
grammatical corrections in caption
The Glasgow-Maastricht foot model, evaluation of a 26 segment kinematic model of the foot
BACKGROUND: Accurately measuring of intrinsic foot kinematics using skin mounted markers is difficult, limited in part by the physical dimensions of the foot. Existing kinematic foot models solve this problem by combining multiple bones into idealized rigid segments. This study presents a novel foot model that allows the motion of the 26 bones to be individually estimated via a combination of partial joint constraints and coupling the motion of separate joints using kinematic rhythms. METHODS: Segmented CT data from one healthy subject was used to create a template Glasgow-Maastricht foot model (GM-model). Following this, the template was scaled to produce subject-specific models for five additional healthy participants using a surface scan of the foot and ankle. Forty-three skin mounted markers, mainly positioned around the foot and ankle, were used to capture the stance phase of the right foot of the six healthy participants during walking. The GM-model was then applied to calculate the intrinsic foot kinematics. RESULTS: Distinct motion patterns where found for all joints. The variability in outcome depended on the location of the joint, with reasonable results for sagittal plane motions and poor results for transverse plane motions. CONCLUSIONS: The results of the GM-model were comparable with existing literature, including bone pin studies, with respect to the range of motion, motion pattern and timing of the motion in the studied joints. This novel model is the most complete kinematic model to date. Further evaluation of the model is warranted
Vorticity alignment results for the three-dimensional Euler and Navier-Stokes equations
We address the problem in Navier-Stokes isotropic turbulence of why the
vorticity accumulates on thin sets such as quasi-one-dimensional tubes and
quasi-two-dimensional sheets. Taking our motivation from the work of Ashurst,
Kerstein, Kerr and Gibson, who observed that the vorticity vector
{\boldmath\omega} aligns with the intermediate eigenvector of the strain
matrix , we study this problem in the context of both the three-dimensional
Euler and Navier-Stokes equations using the variables \alpha =
\hat{{\boldmath\xi}}\cdot S\hat{{\boldmath\xi}} and {\boldmath\chi} =
\hat{{\boldmath\xi}}\times S\hat{{\boldmath\xi}} where
\hat{{\boldmath\xi}} = {\boldmath\omega}/\omega. This introduces the
dynamic angle , which lies between
{\boldmath\omega} and S{\boldmath\omega}. For the Euler equations a
closed set of differential equations for and {\boldmath\chi} is
derived in terms of the Hessian matrix of the pressure . For
the Navier-Stokes equations, the Burgers vortex and shear layer solutions turn
out to be the Lagrangian fixed point solutions of the equivalent
(\alpha,{\boldmath\chi}) equations with a corresponding angle .
Under certain assumptions for more general flows it is shown that there is an
attracting fixed point of the (\alpha,\bchi) equations which corresponds to
positive vortex stretching and for which the cosine of the corresponding angle
is close to unity. This indicates that near alignment is an attracting state of
the system and is consistent with the formation of Burgers-like structures.Comment: To appear in Nonlinearity Nov. 199
Separation between coherent and turbulent fluctuations. What can we learn from the Empirical Mode Decomposition?
The performances of a new data processing technique, namely the Empirical
Mode Decomposition, are evaluated on a fully developed turbulent velocity
signal perturbed by a numerical forcing which mimics a long-period flapping.
First, we introduce a "resemblance" criterion to discriminate between the
polluted and the unpolluted modes extracted from the perturbed velocity signal
by means of the Empirical Mode Decomposition algorithm. A rejection procedure,
playing, somehow, the role of a high-pass filter, is then designed in order to
infer the original velocity signal from the perturbed one. The quality of this
recovering procedure is extensively evaluated in the case of a "mono-component"
perturbation (sine wave) by varying both the amplitude and the frequency of the
perturbation. An excellent agreement between the recovered and the reference
velocity signals is found, even though some discrepancies are observed when the
perturbation frequency overlaps the frequency range corresponding to the
energy-containing eddies as emphasized by both the energy spectrum and the
structure functions. Finally, our recovering procedure is successfully
performed on a time-dependent perturbation (linear chirp) covering a broad
range of frequencies.Comment: 23 pages, 13 figures, submitted to Experiments in Fluid
Renormalization group in the infinite-dimensional turbulence: third-order results
The field theoretic renormalization group is applied to the stochastic
Navier-Stokes equation with the stirring force correlator of the form
k^(4-d-2\epsilon) in the d-dimensional space, in connection with the problem of
construction of the 1/d expansion for the fully developed fluid turbulence
beyond the scope of the standard epsilon expansion. It is shown that in the
large-d limit the number of the Feynman diagrams for the Green function (linear
response function) decreases drastically, and the technique of their analytical
calculation is developed. The main ingredients of the renormalization group
approach -- the renormalization constant, beta function and the ultraviolet
correction exponent omega, are calculated to order epsilon^3 (three-loop
approximation). The two-point velocity-velocity correlation function, the
Kolmogorov constant C_K in the spectrum of turbulent energy and the
inertial-range skewness factor S are calculated in the large-d limit to third
order of the epsilon expansion. Surprisingly enough, our results for C_K are in
a reasonable agreement with the existing experimental estimates.Comment: 30 pages with EPS figure
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