1,768 research outputs found

    Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases

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    Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported cases has fallen to a historically low level. Although fewer than 977 cases were reported in 2018 in endemic countries, HAT is still a public health problem in endemic regions until it is completely eliminated. In addition, almost 150 confirmed HAT cases were reported in non-endemic countries in the last three decades. The majority of non-endemic HAT cases were reported in Europe, United States and South Africa, due to historical alliances, economic links or geographic proximity to disease endemic countries. Furthermore, with the implementation of the “Belt and Road” project, sporadic imported HAT cases have been reported in China as a warning sign of tropical diseases prevention. In this paper, we explore and interpret the data on HAT incidence and find no positive correlation between the number of HAT cases from endemic and non-endemic countries.This data will provide useful information for better understanding the imported cases of HAT globally in the post-elimination phase

    Continuum modelling of granular particle flow with inelastic inter-particle collisions

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    The kinetic theory of granular flow is a successful model for gas-solid flows. However, inelastic collisions between particles, among other mechanisms, cause agglomeration of particles, which may be the reason why undue sensitivity of the model to any slight inelasticity in inter-particle collisions has been seen previously. In contrast to a dry (i.e. no interstitial gas) granular system, this tendency to agglomerate in a gas driven two-phase system may be countered by the carrier gas turbulence. In this paper, a heuristic model for particle gas turbulence interaction is introduced within the scope of a generalized kinetic theory model which incorporates the carrier fluid effect on particulate stresses. The numerical results for the flow of granular particles in vertical pipes, which considers slightly inelastic inter-particle collisions, are in reasonably good agreement with published experimental data. Even in this relatively simple model, the results indicate that the interactions between the particle phase and gas turbulence need to be appropriately addressed in any kinetic theory based model for gas solid flows

    Linear quadratic regulation of polytopic time-inhomogeneous Markov jump linear systems (extended version)

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    In most real cases transition probabilities between operational modes of Markov jump linear systems cannot be computed exactly and are time-varying. We take into account this aspect by considering Markov jump linear systems where the underlying Markov chain is polytopic and time-inhomogeneous, i.e. its transition probability matrix is varying over time, with variations that are arbitrary within a polytopic set of stochastic matrices. We address and solve for this class of systems the infinite-horizon optimal control problem. In particular, we show that the optimal controller can be obtained from a set of coupled algebraic Riccati equations, and that for mean square stabilizable systems the optimal finite-horizon cost corresponding to the solution to a parsimonious set of coupled difference Riccati equations converges exponentially fast to the optimal infinite-horizon cost related to the set of coupled algebraic Riccati equations. All the presented concepts are illustrated on a numerical example showing the efficiency of the provided solution.Comment: Extended version of the paper accepted for the presentation at the European Control Conference (ECC 2019

    The Granular Phase Diagram

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    The kinetic energy distribution function satisfying the Boltzmann equation is studied analytically and numerically for a system of inelastic hard spheres in the case of binary collisions. Analytically, this function is shown to have a similarity form in the simple cases of uniform or steady-state flows. This determines the region of validity of hydrodynamic description. The latter is used to construct the phase diagram of granular systems, and discriminate between clustering instability and inelastic collapse. The molecular dynamics results support analytical results, but also exhibit a novel fluctuational breakdown of mean-field descriptions.Comment: 15 pages, 4 figure

    Optimized acquisition time and image sampling for dynamic SPECT of Tl-201

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    Author name used in this publication: Dagan FengAuthor name used in this publication: Pak-Kong LunVersion of RecordPublishe

    Fragmented and Single Condensate Ground States of Spin-1 Bose Gas

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    We show that the ground state of a spin-1 Bose gas with an antiferro- magnetic interaction is a fragmented condensate in uniform magnetic fields. The number fluctuations in each spin component change rapidly from being enormous (order NN) to exceedingly small (order 1) as the magnetization of the system increases. A fragmented condensate can be turned into a single condensate state by magnetic field gradients. The conditions for existence and the method of detecting fragmented states are presented.Comment: 4 pages, no figure
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