17 research outputs found
Obesity and asthma: an association modified by age
[Abstract] Background. Some studies indicate some causal relationship between obesity and asthma, while others show inconsistent results. Our objective was to evaluate the prevalence of asthma according to obesity in children.
Methods. A cross-sectional study, following the ISAAC study methodology, was conducted on two randomly selected groups consisting of 6â7 year-old children (n = 7485) and 13â14 year-old adolescents (n = 8496).
The asthma symptoms and potential risk factors were determined from the questionnaire. Overweight and obesity were defined based on the body mass index.
Multiple logistic regression was used to obtain adjusted prevalence odds ratios (OR) and 95% confidence intervals.
Results. Obesity was associated with an increase in wheezing ever (OR: 1.35) and exercise-induced asthma (OR: 1.62) in the 6â7 year-old group. No significant relationship was observed in the adolescent population.
Conclusion. Obesity was associated with a higher prevalence of asthma in young children, but not in adolescents
Prevalence and Geographic Variations in Asthma Symptoms in Children and Adolescents in Galicia (Spain)
[Resumen] Objetivos. Determinar la prevalencia y variaciones geogrĂĄficas de sĂntomas relacionados con asma en niños y adolescentes gallegos.
PoblaciĂłn y mĂ©todos. Estudio transversal segĂșn la metodologĂa ISAAC (Internacional Study of Asthma and Allergies in Childhood) mediante cuestionario escrito distribuido en el medio escolar. Se incluyeron 10.371 niños de 6-7 años y 10.372 adolescentes de 13-14 años de todas las Ăreas Sanitarias de Galicia. Se analizaron las variaciones geogrĂĄficas mediante un modelo de regresiĂłn logĂstica.
Resultados. Las sibilancias en los Ășltimos 12 meses oscilaron en los pequeños, del 11,4 (Santiago) al 15,7% (Vigo) y en los adolescentes del 8,8 (Ourense) al 18,8% (Vigo). SegĂșn el gĂ©nero se observĂł una mayor frecuencia en varones de 6-7 años (p < 0,001) y con tendencia a la significaciĂłn estadĂstica en las chicas de 13-14 años (p = 0,08). El riesgo (Odds ratio [OR]) de sibilancias en los Ășltimos 12 meses, en el ĂĄrea de mayor prevalencia con respecto a la de menor, fue 1,45 (intervalo de confianza [IC] del 95%: 1,12-1,88) en niños y 2,39 (IC 95%: 1,82-3,13) en adolescentes. La prevalencia de asma estimada para Galicia fue de 13,6% en niños y 12,2% en adolescentes.
Conclusiones. La prevalencia de sibilancias en los Ășltimos 12 meses en las diferentes ĂĄreas gallegas es sensiblemente superior al resto de ciudades españolas participantes en el ISAAC en los pequeños, siendo muy similar en los adolescentes, salvo en Vigo donde es sensiblemente superior. Encontramos un patrĂłn geogrĂĄfico muy definido en los adolescentes, siendo mayores las prevalencias en la costa que en el interior.[Abstract] Objectives. To determine the prevalence and geographic variations of the symptoms associated with asthma in Galician children and adolescents.
Population and methods. A cross-sectional epidemiological study following ISAAC (International Study of Asthma and Allergies in Childhood) methodology, and using a written questionnaire distributed in schools. The study sample included 10,371 6-7 year-old children and 10,372 13-14 year-old adolescents, all of them from Galician Health Areas. A logistic regression model was used to analyse geographic variations.
Results. In the 6-7 year-old group, wheezing in the last 12 months varied from 11.4% (Santiago) to 15.7% (Vigo) and in the adolescents varied from 8.8% (Ourense) to 18.8% (Vigo). The distribution by gender showed a predominant significance in 6-7 year-old males (P < .001), and near to be statistically significant in 13-14 year-old females (P = .08). The risk (odds ratio [OR]) of wheezing in the last 12 months in the area with highest prevalence in comparison with the area of lowest prevalence was 1.45 (95% Confidence Interval [CI], 1.12-1.88) for children and 2.39 (95% CI, 1.82-3.13) for adolescents. The estimated prevalence of asthma in the Autonomous Community of Galicia was 13.6% in younger children and 12.2% in adolescents.
Conclusions. The prevalence of wheezing in the last 12 months in the different areas of Galicia is considerably higher than the rest of Spanish ISAAC cities in the 6-7 years group and very similar in the 13-14 years group, except in Vigo where it is considerably higher. We found a clearly defined geographic pattern in the adolescent group, with higher prevalences in coastal areas than in the interior
Impact of parental smoking on childhood asthma
[Abstract] Objective: To evaluate the exposure to environmental tobacco smoke (ETS) of the childhood population in this community and its relationship with asthma symptoms.
Methods: A cross-sectional study was conducted using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire on children and adolescents in this community. The symptoms "wheezing ever", "current asthma", "severe asthma", and "exercise-induced asthma" were defined by this questionnaire. Parental smoking was classified into four mutually exclusive categories: 1) no parent smokes; 2) only the mother smokes; 3) only the father smokes; and 4) both parents smoke. The odds ratio of the prevalence of asthma symptoms according to ETS exposure was calculated using logistic regression.
Results: A total of 10,314 children and 10,453 adolescents were included. Over 51% of the children and adolescents were exposed to ETS at home. ETS is associated with a higher prevalence of asthma symptoms, particularly if the mother or both parents smoke.
Conclusion: The prevalence of ETS is still high in this community, although there has been a decreasing tendency in the last 15 years. ETS is associated with higher prevalence of asthma
Crossâsectional study about impact of parental smoking on rhinitis symptoms in children
[Abstract]
Objective. Assess the prevalence of rhinitis and exposure to environmental tobacco smoke (ETS) of children in our community and its relationship with symptoms of rhinitis
Methods (design, setting, participants, main outcome measures). Crossâsectional study using questionnaire on rhinitis of the International Study of Asthma and Allergies in Childhood, in children (6â7 years) and adolescents (13â14 years). Categories: ârhinitis everâ, ârecent rhinitisâ, ârecent rhinoconjunctivitisâ, âsevere rhinoconjunctivitisâ. Parental smoking: (i) neither parent smokes; (ii) only the mother smokes; (iii) only the father smokes; and (iv) both parents smoke. Odds ratio of the prevalence of symptoms of rhinitis according to ETS exposure was calculated using logistic regression.
Results. 10 690 children and 10 730 adolescents. The prevalence of ârhinitis everâ in children: 29.4%, ârecent rhinitisâ 24%, ârecent rhinoconjunctivitisâ 11.5% and âsevere rhinoconjunctivitisâ 0.1%. In adolescents: 46.2%, 34.5%, 16.2% and 0.2%, respectively. Environmental tobacco smoke exposure in the home occurred in 51% of cases. Parental smoking was associated with a higher prevalence of forms of rhinitis in adolescents when only the mother was a smoker. In children when both parents were smokers.
Conclusion. Rhinitis is highly prevalent in our community. Environmental tobacco smoke exposure is still very common. The relationship between ETS and rhinitis symptoms in children of this community is not as robust as that found for asthma
Exposure to paracetamol and asthma symptoms
Multicenter study[Abstract] Background: Paracetamol is one of the factors that have been associated with the observed increase in asthma prevalence in the last few years. The influence of environmental or genetic factors in this disease may be different in some countries than in others. The purpose of this study was to analyse the relationship between the paracetamol consumption and asthma prevalence in our community.
Methods: A cross-sectional study was conducted on more than 20,000 children and adolescents in Galicia, Spain. The International Study of Asthma and Allergies in Childhood methodology was used to collect the information on asthma symptoms in children, paracetamol consumption, body mass index (BMI), pets in the home, education level of the mother and parental asthma and smoking habits. The influence of paracetamol consumption on the prevalence of asthma symptoms was calculated using logistic regression, adjusted for the other parameters included in the study.
Results: After adjusting for gender, BMI, having a cat or dog, maternal education, parental asthma and smoking, in 6- to 7-year-old children, the consumption of paracetamol during the first year of life is associated with asthma [odds ratio (OR) 2.04 (1.79-2.31) for wheezing at some time]. Paracetamol consumption in the previous year leads to a significant increase in the probability of wheezing at some time [OR 3.32 (2.51-4.41)] in young children and adolescents [OR 2.12 (1.68-2.67)].
Conclusions: Paracetamol consumption is associated with a significant increase in asthma symptoms. The effect is greater the more often the drug is taken
Association of Rhinitis With Asthma Prevalence and Severity
Multicenter study[Abstract] Asthma and rhinitis often co-exist in the same patient. Although some authors observed a higher prevalence and/or greater severity of asthma in patients with rhinitis, this view is not homogeneous and the debate continues. The aim of our study is to describe the prevalence of rhinitis in children and adolescents and to analyse their relationship with the prevalence of asthma. A multicentre study was conducted using the methodology of the International Study of Asthma and Allergies in Childhood (ISAAC). The target population of the study was all those school children aged 6-7 and 13-14 years from 6 of the main health catchment areas of Galicia (1.9 million inhabitants). The schools required were randomly selected, and all children in the targeted age ranges were included. Multiple logistic regression was used to obtain adjusted prevalence odds ratios (OR) between asthma symptoms of the schoolchildren and rhinitis prevalence. The results were adjusted for parental smoking habits, maternal education level, cat and dog exposure, and obesity. A total of 21,420 valid questionnaires were finally obtained. Rhinitis was associated with a significant increase in the prevalence of asthma in both age groups. The highest OR were 11.375 for exercise induced asthma (EIA) for children with recent rhinoconjunctivitis and 9.807 for children with recent rhinitis in 6-7 years old group. The prevalence OR's are higher in EIA and severe asthmatics. Rhinitis in children and adolescents is associated with a higher prevalence and severity of asthma.This work was funded by the Maria Jose Jove Foundatio
Prevalencia de sĂntomas de asma en los niños y adolescentes de la Comunidad AutĂłnoma de Galicia (España) y sus variaciones geogrĂĄficas
OBJECTIVES: To determine the prevalence and geographic variations of the symptoms associated with asthma in Galician children and adolescents. POPULATION AND METHODS: A cross-sectional epidemiological study following ISAAC (International Study of Asthma and Allergies in Childhood) methodology, and using a written questionnaire distributed in schools. The study sample included 10,371 6-7 year-old children and 10,372 13-14 year-old adolescents, all of them from Galician Health Areas. A logistic regression model was used to analyse geographic variations. RESULTS: In the 6-7 year-old group, wheezing in the last 12 months varied from 11.4% (Santiago) to 15.7% (Vigo) and in the adolescents varied from 8.8% (Ourense) to 18.8% (Vigo). The distribution by gender showed a predominant significance in 6-7 year-old males (P<.001), and near to be statistically significant in 13-14 year-old females (P=.08). The risk (odds ratio [OR]) of wheezing in the last 12 months in the area with highest prevalence in comparison with the area of lowest prevalence was 1.45 (95% Confidence Interval [CI], 1.12-1.88) for children and 2.39 (95% CI, 1.82-3.13) for adolescents. The estimated prevalence of asthma in the Autonomous Community of Galicia was 13.6% in younger children and 12.2% in adolescents. CONCLUSIONS: The prevalence of wheezing in the last 12 months in the different areas of Galicia is considerably higher than the rest of Spanish ISAAC cities in the 6-7 years group and very similar in the 13-14 years group, except in Vigo where it is considerably higher. We found a clearly defined geographic pattern in the adolescent group, with higher prevalences in coastal areas than in the interior
Impact of parental smoking on childhood asthma
Objetive: To evaluate the exposure to environmental tobacco smoke (ETS) of the child- hood population in this community and its relationship with asthma symptoms.
Methods: A cross-sectional study was conducted using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire on children and adolescents in this community. The symptoms âwheezing everâ, âcurrent asthmaâ, âsevere asthmaâ, and âexercise-induced asthmaâ were defined by this questionnaire. Parental smoking was classified into four mutually exclusive categories: 1) no parent smokes; 2) only the mother smokes; 3) only the father smokes; and 4) both parents smoke. The odds ratio of the prevalence of asthma symptoms according to ETS exposure was calculated using logistic regression.
Results: A total of 10,314 children and 10,453 adolescents were included. Over 51% of the children and adolescents were exposed to ETS at home. ETS is associated with a hig- her prevalence of asthma symptoms, particularly if the mother or both parents smoke.
Conclusion: The prevalence of ETS is still high in this community, although there has been a decreasing tendency in the last 15 years. ETS is associated with higher prevalence of asthma