Effect of unsaturated fatty acid supplementation on digestion, metabolism and nutrient balance in dairy cows during the transition period and early lactation

The objective of this study was to evaluate the influence of unsaturated fatty acids in diets for dairy cows during the transition period and early lactation on intake, digestion and nutrient balance. Thirty-six multiparous and pregnant Holstein cows were randomly distributed to receive one of the experimental diets in the period from 35 days before the expected date of parturition to 84 days post-partum. Diets were fed as a total mixed ration and were as follows: control (C); soybean oil (SO), based on inclusion of 30 g/kg (DM basis); and calcium salts of unsaturated fatty acids (CS), based on inclusion of 30 g/kg (DM basis). Pre-partum dry matter intakes (DMI) of cows fed C, SO and CS were 11.9, 9.5 and 9.6 kg/d, respectively. Postpartum DMI was affected by experimental diets (18.5, 15.0 and 17.4 kg/d for C, SO and CS, respectively). The energy balance in the transition period of animals fed CS was 4.41 Mcal/d higher than cows fed SO and 1.3 Mcal/d higher than cows fed C. Supplementing cows with unsaturated fatty acid sources is a strategy for dairy cows in the transition perio

Impact of Wearing Palatal Expanders on the Quality of Life of Children Aged 8 to 10 Years

Objective: To assess the impact of wearing palatal expanders on the oral health-related quality of life (OHRQoL) of children aged 8 to 10 years. Material and Methods: The sample consisted of 35 children aged 8 to 10 years treated at the orthodontics and pediatric dentistry outpatient clinics affiliated with the Dental School. Children were divided in two groups: 17 were submitted to palatal expansion treatment (Group 1), while 18 just received coronal polishing and topical fluoride application (Group 2). The Brazilian version of the Child Perceptions Questionnaire (CPQ8-10) was used to assess children’s OHRQoL. The questionnaire was administered before the expander was placed, at the end of its activation, and before its removal. Intervals between the interviews were similar in the two groups. Descriptive statistics and ANOVA were used for data analyses. Results: The overall CPQ8-10 score was not significantly different between the groups. The results show statistically significant differences between the two groups only for the functional limitations domain after activation of the appliance (p=0.001). Conclusion: Palatal expanders may negatively affect children's functions only during the initial wearing period

Major clinical evidence of cervicofacial liposculpture: a concise systematic review

Introduction: Liposculpture (LS) can complement cervicofacial aging surgery. Modern trends in face sculpting are expanding and adipose tissue transfer can result in optimal esthetic effects with minimally invasive techniques. Facial LS focuses on repositioning adipose tissue and increasing facial transition zones. This is accomplished using internal suspension sutures as well as with autologous fat grafting. Objective: To carry out a concise systematic review of the main clinical considerations and advances in facial and cervical liposculpture as an important aesthetic tool for dental surgeons. Methods: The rules of the Systematic Review-PRISMA Platform were followed. The search was carried out from November 2021 to February 2022 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: Fifty articles were found involving facial liposculpture. A total of 30 articles were fully evaluated and 16 were included and developed in the present study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 10 studies at high risk of bias and 4 studies that did not meet the GRADE. Most patients who were involved in the studies showed improvements in facial augmentation and contouring. In patients with loss of facial volume, high-density fat transfer with SVF-gel facial injection resulted in significantly higher improvement scores and better patient satisfaction, with an improved/much improved esthetic appearance being observed. As a follow-up analysis of the studies, at an average of six months after completion, most patients were satisfied with the results. All procedures were well tolerated. Conclusion: According to the main clinical studies selected in the present study, cervicofacial liposculpture proved to be advantageous, with safety and efficacy

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Apoptose na eliminação pulpar durante a reabsorção radicular fisiológica de dentes decíduos humanos

Exportado OPUSMade available in DSpace on 2019-08-14T21:17:35Z (GMT). No. of bitstreams: 1 luvillelams.pdf: 1302699 bytes, checksum: 4dacf6423f1cd351f705092791c19349 (MD5) Previous issue date: 15Cinqüenta amostras de polpas de dentes humanos foram estudadas a fim de avaliar a participação da apoptose na eliminação pulpar durante a reabsorção radicular fisiológica. As amostras foram divididas em dois grupos: um grupo de polpas de dentes decíduos hígidos (n=30), com reabsorção radicular fisiológica e um grupo controle (n=20), formado por amostras pulpares de terceiros molares superiores hígidos. Todos os dentes já tinham exodontia indicada por motivos alheios a este estudo. As células foram coradas em HE e quantificadas através da morfologia. A apoptose foi confirmada pela reação de TUNEL e pela eletroforese do DNA visualizando-se o padrão de fragmentação internucleossõmica do genoma. O índice apoptótico foi maior no grupo de dentes decíduos (51,01 ± 0,52) quando comparado ao grupo controle (25,32 ± 0,68) formado por dentes permanentes (P<0.001). Na Reação de TUNELhouve ampla marcação positiva para fragmentação do genoma no grupo de estudo. Na eletroforese do DNA em gel de agarose observou-se, neste mesmo grupo, o padrão de fragmentação internucleossõmica do DNA genômico da apoptose. Tais achados foram encontrados de maneira mais discreta nas amostras de dentes permanentes. Considerando o maior índice apoptótico associado à mais ampla marcação positiva in situ para a fragmentação do DNA genômico (TUNEL) e à detecção do clássico padrão em escada na eletroforeseem gel de agarose nas polpas de dentes decíduos, pode-se inferir que a apoptose exerce um papel importante de eliminação pulpar durante areabsorção radicular fisiológica dos dentes decíduos humanos.Fifty healthy human teeth pulp samples were studied to evaluate the role of apoptosis in pulp elimination during physiological root resorption. The samples were splitted in two groups: a group of deciduous teeth (n=30), with physiological root resorption, and a control group (n=20), with pulps of permanent superior third molar teeth, which do not undergo physiological root resorption. All the teeth already had extraction indicated by other reasons. The pulp samples were processed for routine histological examination and were submitted to morphometrical analysis. Also DNA was extracted and an agarose gel electrophoresis of the genomic DNA was performed. Apoptotic cells were quantified by morphology and confirmed by in situ detection of the genomicfragmentation (TUNEL) and by the ladder pattern at the DNA electrophoresis. The apoptotic index of the group of deciduous teeth (51,01±0,52) was significantly higher than in the control group (25.32± 0,68) (P<0.001). TUNEL Reaction showed intense and diffuse labeling in samples of deciduous teeth, which were not present in controls. The ladder pattern at the DNA electrophoresis was evident in samples of deciduous teeth, and not present in controls. These results seem to indicate a role of apoptosis in pulp elimination during the physiological radicular resorption of human deciduous teeth

Effect of unsaturated fatty acid supplementation on digestion, metabolism and nutrient balance in dairy cows during the transition period and early lactation

The objective of this study was to evaluate the influence of unsaturated fatty acids in diets for dairy cows during the transition period and early lactation on intake, digestion and nutrient balance. Thirty-six multiparous and pregnant Holstein cows were randomly distributed to receive one of the experimental diets in the period from 35 days before the expected date of parturition to 84 days post-partum. Diets were fed as a total mixed ration and were as follows: control (C); soybean oil (SO), based on inclusion of 30 g/kg (DM basis); and calcium salts of unsaturated fatty acids (CS), based on inclusion of 30 g/kg (DM basis). Pre-partum dry matter intakes (DMI) of cows fed C, SO and CS were 11.9, 9.5 and 9.6 kg/d, respectively. Post-partum DMI was affected by experimental diets (18.5, 15.0 and 17.4 kg/d for C, SO and CS, respectively). The energy balance in the transition period of animals fed CS was 4.41 Mcal/d higher than cows fed SO and 1.3 Mcal/d higher than cows fed C. Supplementing cows with unsaturated fatty acid sources is a strategy for dairy cows in the transition period

Influência da perda óssea e da inclinação do incisivo na distribuição de tensões perirradiculares decorrentes da simulação de forças oclusais

Made available in DSpace on 2019-09-11T20:58:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2018Resumo Introdução Adultos com sequelas de doenças periodontais tendem a apresentar perda óssea, com consequente vestibularização dos incisivos superiores. Objetivo A influência da perda óssea e da inclinação do incisivo superior na distribuição de tensões devido a forças mastigatórias simuladas foram avaliadas nesse estudo. Material e método Modelos em resina epóxi foram confeccionados em três condições (sem perda óssea e com perda óssea de 5mm e 8mm). Aumentos na inclinação vestibular do incisivo superior de 10° e 20° foram obtidos com um bloco metálico chanfrado. Cargas de 100N foram aplicadas cinco vezes em cada condição usando uma máquina de ensaio universal. Os modelos foram observados e filmados com um polariscópio circular. Ordens de franjas isocromáticas (tensões) nas faces vestibular, lingual e apical foram registradas. A concordância dos dados foi avaliada pelo teste kappa ponderado e os resultados foram 0,89 e 0,82 para intra e interexaminadores, respectivamente. Resultado Os resultados dos testes de Kruskal-Wallis e SNK indicaram maiores tensões (2,0) com aumento da inclinação vestibular na face vestibular; maiores tensões (2,67) com aumento da perda óssea; maior tensão com a associação de perda óssea e inclinação vestibular (3,6); e as maiores tensões tenderam a concentrar-se na face vestibular, exceto em casos de inclinação normal e sem perda óssea (0,45). Conclusão Concluiu-se que aumentos tanto da inclinação vestibular dos incisivos superiores quanto da perda óssea aumentam as tensões perirradiculares, e a combinação desses fatores aumenta ainda mais as tensões devido às forças mastigatórias, com a maior concentração na face vestibular.Abstract Introduction Adults with sequelae of periodontal disease tend to have bone loss, with consequent flaring of the maxillary incisors. Objective The influence of bone loss and the inclination of the maxillary incisor in the distribution of stresses due to simulated bite forces was studied. Material and method Models in epoxy resin were made in three conditions (without bone loss and with bone loss of 5mm and 8mm). Increases in the labial inclination of the maxillary incisor of 10° and 20° were obtained with a beveled metallic block. Loads of 100N were applied five times in each condition using a universal test machine. The models were observed and filmed with a circular polariscope. Orders of isochromatic fringes (stresses) on the labial, lingual, and apex surfaces were recorded. The agreement of the data was evaluated using the weighted kappa test, and the results were 0.89 and 0.82 for intra- and inter-examiners, respectively. Result The results of the Kruskal–Wallis and SNK tests indicated higher stresses (2.0) with increased labial inclination in the labial surface; higher stresses (2.67) with increased bone loss; higher greater stresses with the association of bone loss and labial-inclination (3.6); and the highest stresses tended to concentrate on the labial surfaces, except in cases of normal inclination and without bone loss (0.45). Conclusion It was concluded that increases in both the labial inclination of the maxillary incisors and bone loss increase periradicular stresses, and the combination of these factors further increases the stresses due to bite forces, with the highest concentration on the labial side.[CLARO, Ana Paula Rosifini Alves] Universidade Estadual Paulista, BrazilRODRIGUES, Samuel; CORTELLI, José Roberto; CHAGAS, Rosana Villela; CONCÍLIO, Lais Regiane da Silva; ARCAS, Luciana Paula Benicio; CLARO, Cristiane Aparecida de Assis] Universidade de Taubaté, Brazi

Influence of bone loss and inclination of incisor on periradicular stresses due to simulated bite force

Abstract Introduction Adults with sequelae of periodontal disease tend to have bone loss, with consequent flaring of the maxillary incisors. Objective The influence of bone loss and the inclination of the maxillary incisor in the distribution of stresses due to simulated bite forces was studied. Material and method Models in epoxy resin were made in three conditions (without bone loss and with bone loss of 5mm and 8mm). Increases in the labial inclination of the maxillary incisor of 10° and 20° were obtained with a beveled metallic block. Loads of 100N were applied five times in each condition using a universal test machine. The models were observed and filmed with a circular polariscope. Orders of isochromatic fringes (stresses) on the labial, lingual, and apex surfaces were recorded. The agreement of the data was evaluated using the weighted kappa test, and the results were 0.89 and 0.82 for intra- and inter-examiners, respectively. Result The results of the Kruskal–Wallis and SNK tests indicated higher stresses (2.0) with increased labial inclination in the labial surface; higher stresses (2.67) with increased bone loss; higher greater stresses with the association of bone loss and labial-inclination (3.6); and the highest stresses tended to concentrate on the labial surfaces, except in cases of normal inclination and without bone loss (0.45). Conclusion It was concluded that increases in both the labial inclination of the maxillary incisors and bone loss increase periradicular stresses, and the combination of these factors further increases the stresses due to bite forces, with the highest concentration on the labial side