Questionário de Hábitos de Estudo para estudantes universitários: validação e precisão

This study presents and discusses the construction of an instrument to evaluate study habits. The digitalized questionnaire entitled Study Habits Questionnaire directed to college students, composed of 97 items with a Likert scale, was applied to 781 undergraduate students enrolled in 10 courses from a private college in the interior of São Paulo, Brazil to evaluate the reliability of psychometric parameters (internal consistency) and validity (factorial analysis). The results indicated nine specific factors with eigenvalue above 1.5. The internal consistency of the factors presented Cronbachs Alpha between 0.603 and 0.934. The conclusion is that the questionnaire presents satisfactory psychometric parameters and is a useful instrument to investigate study habits in undergraduate students with characteristics similar to this studys sample.El objetivo del trabajo es presentar informaciones sobre la construcción de un instrumento para la evaluación de hábitos de estudio. El cuestionario informatizado titulado Cuestionario de Hábitos de Estudio para estudiantes universitarios, compuesto por 97 artículos en escala del tipo Likert, fue aplicado a 781 estudiantes universitarios de 10 cursos de una institución privada en São Paulo para evaluar los parámetros psicométricos de precisión (consistencia interna) y validad (análisis factorial). Los resultados indicaron 9 factores específicos con valores propios (eigenvalues) superiores a 1,5. La consistencia interna de los factores indicó alfa de Cronbach entre 0,603 y 0,934. Se concluyó que el cuestionario presenta parámetros psicométricos satisfactorios, siendo así un instrumento de utilidad en la investigación de los hábitos de estudio de los estudiantes universitarios con las características de esta muestra.Este artigo apresenta e discute a construção de um instrumento para avaliação de hábitos de estudo. O questionário informatizado com o título Questionário de Hábitos de Estudo para estudantes universitários, composto por 97 itens em escala de tipo Likert, foi aplicado a 781 graduandos de 10 cursos de uma instituição particular do interior paulista, para avaliar os parâmetros psicométricos de precisão (consistência interna) e validade (análise fatorial). Os resultados apontaram nove fatores específicos com eigenvalue superior a 1,5. A consistência interna dos fatores apresentou alfa de Cronbach entre 0,603 e 0,934. Concluiu-se que o questionário apresenta parâmetros psicométricos satisfatórios, habilitando-o como instrumento útil na investigação de hábitos de estudo em universitários com as características da presente amostra

Minha profissão é a literatura : travessias da autoria feminina

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Definition and use of the variable "race" by medical students in Salvador, Brazil

CONTEXT AND OBJECTIVE: The lack of a clear definition for human "race" and the importance of this topic in medical practice continue to create doubt among scholars. Here, we evaluate the use of the variable "race" by medical students in Salvador, Brazil. DESIGN AND SETTING: Cross-sectional study at a Brazilian federal public university. METHODS: 221 randomly selected subjects were included. A semi-structured questionnaire was used for data collection. The results were expressed as means and standard deviations of the mean, proportions and frequencies. The χ2 (chi-square) test was used for the statistical calculations. RESULTS: Approximately half of the students (45.4%) used the racial group variable in their studies on clinical practice. Of these, 86.8% considered it to be relevant information in the medical records and 92.7%, important for diagnostic reasoning; 95.9% believed that it influenced the cause, expression and prevalence of diseases; 94.9% affirmed that it contributed towards estimating the risk of diseases; 80.5% thought that the therapeutic response to medications might be influenced by racial characteristics; 41.9% considered that its inclusion in research was always recommendable; and 20.3% thought it was indispensable. The main phenotypic characteristics used for racial classification were: skin color (93.2%), hair type (45.7%), nose shape (33.9%) and lip thickness (30.3%). CONCLUSIONS: Despite the importance of different racial groups in medical practice, the majority of the professionals do not use or know how to classify them. It is necessary to add to and/or expand the discussion of racial and ethnic categories in medical practice and research

Trichuris sp. from 1,040 +/- 50-year-old Cervidae coprolites from the archaeological site Furna do Estrago, Pernambuco, Brazil

We present results of the paleoparasitological analysis of Cervidae coprolites that were recovered from the archaeological site Furna do Estrago, Pernambuco, Brazil. Trichuris sp. eggs were recovered from the coprolite samples dated 1,040 ± 50 years before present. This is the first record of Trichuris sp. in semiarid Cervidae, unexpectedly recorded in archaeological material

Association of rs1285933 single nucleotide polymorphism in CLEC5A gene with dengue severity and its functional effects

Submitted by Sandra Infurna ([email protected]) on 2017-10-17T15:12:34Z No. of bitstreams: 1 caroline_carvalho_etal_IOC_2017.pdf: 1170716 bytes, checksum: 1bbcc0ec40b48fb68c5932c566cca346 (MD5)Approved for entry into archive by Sandra Infurna ([email protected]) on 2017-10-17T15:40:47Z (GMT) No. of bitstreams: 1 caroline_carvalho_etal_IOC_2017.pdf: 1170716 bytes, checksum: 1bbcc0ec40b48fb68c5932c566cca346 (MD5)Made available in DSpace on 2017-10-17T15:40:47Z (GMT). No. of bitstreams: 1 caroline_carvalho_etal_IOC_2017.pdf: 1170716 bytes, checksum: 1bbcc0ec40b48fb68c5932c566cca346 (MD5) Previous issue date: 2017Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Recife, PE, Brasil.Universidade de Pernambuco. Faculdade de Ciências Médicas. Recife, PE, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Universidade Federal do Vale do São Francisco. Colegiado de Ciências Farmacêuticas. Petrolina, PE, Brasil.Universidade de Pernambuco. Faculdade de Ciências Médicas. Recife, PE, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Parasitologia. Laboratório de Doenças Transmissíveis. Ri de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. LAVITE. Recife, PE, Brasil.Universidade de Pernambuco. Faculdade de Ciências Médicas. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Universidade Federal do Mato Grosso do Su. Faculdade de Medicina. Departamento de Genética Médica. Campo Grande, MS, Brasil.Centro de Referência em Dengue e Faculdade de Medicina. Campos de Goytacazes, RJ, Brasil.Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Viral. Rio de Janeiro, RJ, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Recife, PE, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Parasitologia. Laboratório de Doenças Transmissíveis. Ri de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Outbreaks of the Zika, dengue, and chikungunya viruses, especially in the Americas, pose a global threat due to their rapid spread and difficulty controlling the vector. Extreme phenotypes are often observed, from asymptomatic to severe clinical manifestations, which are well-studied in dengue. Host variations are also important contributors to disease outcomes, and many case-control studies have associated single nucleotide polymorphisms (SNPs) with severe dengue. Here, we found that the TC genotype and T-carriers for SNP rs1285933 in the C-type lectin superfamily member 5 (CLEC5A) gene was associated with severe dengue in a Northern Brazilian population (OR=2.75 and p-value=0.01, OR=2.11 and p-value=0.04, respectively). We also tested the functional effect of the CLEC5A protein and found that it is upregulated on the surface of human monocytes after in vitro dengue infection. CLEC5A was correlated with viral load inside the monocytes (Spearman r=0.55, p=0.008) and TNF production in culture supernatants (Spearman r=0.72, p=0.03). Analysis of mRNA in blood samples from DENV4-infected patients exhibiting mild symptoms showed that CLEC5A mRNA expression is correlated with TNF (r=0.67, p=0.0001) and other immune mediators. Monocytes from rs1285933 TT/TC individuals showed lower CLEC5A expression compared to CC genotypes. However, in these cells, CLEC5A was not correlated with TNF production. In summary, we confirmed that CLEC5A is genetically associated with dengue severity outcome, playing a central role during the immune response triggered by a dengue viral infection, and rs1285933 is a relevant SNP that is able to regulate signaling pathways after interactions between the dengue virus and CLEC5A receptors