Embodying Embodied Design Research Techniques

The value of engaging the full gamut of sensory motor skills in the design and use of smart objects and systems is recognized. Yet methods for arriving at robust and reliable outcomes for their development are not fully understood, nor are they easily reported or transferred through typical conference presentations and paper submissions. New forms of knowledge transfer, such as pictorials (e.g., DIS and RTD conferences), and video are enabling enhanced, image-enriched reporting of outcomes. Y et appropriate transfer of embodied research methods remains elusive. In this workshop we propose to investigate how embodied research techniques may be used as direct and unmediated vehicles for their own reporting. Rather than engaging in oral presentations, participants will lead other participants through a proven embodied method or approach. Small groups will create mash-ups of techniques, exploring ways that the new approaches might coherently be reported. Participants will be encouraged to experiment with different recording techniques, including body-mounted sensing and recording devices, as well as less conventional approaches. The intention is to find appropriate ways of reporting embodied experiments, so that intangible elements are not lost. Participants will be supported to reflect on unfolding discoveries, to share impressions, as well as outcomes, including documentation experiments that aim to tangibly capture and communicate the processes undertaken. Embodied ideation, communication and collaboration techniques enable enhanced creative engagement and assist creativity [2]. By applying such methods to the problem of their reporting, we hope to deepen understanding of how to move towards enriched, nuanced and repeatable methods for embodied design and knowledge transfer. Crucially, our intention is not simply to find the next form of research reporting. Rather, this workshop will engage participants in an experimental enquiry, so that embodied design research may become an active area of inquiry moving forward.

H I in group interactions: HCG 44

Extending deep observations of the neutral atomic hydrogen (HI) to the environment around galaxy groups can reveal a complex history of group interactions which is invisible to studies that focus on the stellar component. Hickson Compact Group 44 (HCG 44) is a nearby example and we have combined HI data from the Karoo Array Telescope, Westerbork Synthesis Radio Telescope, and Arecibo Legacy Fast ALFA survey, in order to achieve high column density sensitivity (N_HI < 2x10^18 cm^-2) to the neutral gas over a large field-of-view beyond the compact group itself. We find the giant HI tail north of HCG 44 contains 1.1x10^9 M_Sun of gas and extends 450 kpc from the compact group: twice as much mass and 33% further than previously detected. However, the additional gas is still unable to account for the known HI deficiency of HCG 44. The tail likely formed through a strong tidal interaction and HI clouds in the tail have survived for 1 Gyr or more after being stripped. This has important implications for understanding the survival of neutral clouds in the intragroup and circumgroup medium, and we discuss their survival in the context of simulations of cold gas in hot halos. HCG 44 is one of a growing number of galaxy groups found to have more extended HI in the intragroup and circumgroup medium than previously measured. Our results provide constraints for simulations on the properties of galaxy group halos, and reveal a glimpse of what will be seen by future powerful HI telescopes and surveys.Comment: 12 pages, 6 figures. Accepted for publication in MNRA

Radio Continuum and Star Formation in CO-rich Early Type Galaxies

In this paper we present new high resolution VLA 1.4 GHz radio continuum observations of five FIR bright CO-rich early-type galaxies and two dwarf early-type galaxies. The position on the radio-FIR correlation combined with striking agreements in morphology between high resolution CO and radio maps show that the radio continuum is associated with star formation in at least four of the eight galaxies. The average star formation rate for the sample galaxies detected in radio is approximately 2 solar masses per year. There is no evidence of a luminous AGN in any of our sample galaxies. We estimate Toomre Q values and find that the gas disks may well be gravitationally unstable, consistent with the above evidence for star formation activity. The radio continuum emission thus corroborates other recent suggestions that star formation in early type galaxies may not be uncommon.Comment: 21 pages, 7 figures, to be published in the Astronomical Journa

Constraints on the origin of the radio synchrotron background via angular correlations

The origin of the radio synchrotron background (RSB) is currently unknown. Its understanding might have profound implications in fundamental physics or might reveal a new class of radio emitters. In this work, we consider the scenario in which the RSB is due to extragalactic radio sources and measure the angular cross-correlation of LOFAR images of the diffuse radio sky with matter tracers at different redshifts, provided by galaxy catalogs and CMB lensing. We compare these measured cross-correlations to those expected for models of RSB sources. We find that low-redshift populations of discrete sources are excluded by the data, while higher redshift explanations are compatible with available observations. We also conclude that at least 20\% of the RSB surface brightness level must originate from populations tracing the large-scale distribution of matter in the universe, indicating that at least this fraction of the RSB is of extragalactic origin. Future measurements of the correlation between the RSB and tracers of high-redshift sources will be crucial to constraining the source population of the RSB.Comment: 12 pages, 8 figures. Version accepted for publication in MNRA

Modifiable Cardiovascular Disease Risk Factors among Indigenous Populations

Objective:. To identify modifiable cardio-metabolic and lifestyle risk factors among indigenous populations from Australia (Aboriginal Australians/Torres Strait Islanders), New Zealand (Māori), and the United States (American Indians and Alaska Natives) that contribute to cardiovascular disease (CVD). Methods:. National health surveys were identified where available. Electronic databases identified sources for filling missing data. The most relevant data were identified, organized, and synthesized. Results:. Compared to their non-indigenous counterparts, indigenous populations exhibit lower life expectancies and a greater prevalence of CVD. All indigenous populations have higher rates of obesity and diabetes, hypertension is greater for Māori and Aboriginal Australians, and high cholesterol is greater only among American Indians/Alaska Natives. In turn, all indigenous groups exhibit higher rates of smoking and dangerous alcohol behaviour as well as consuming less fruits and vegetables. Aboriginal Australians and American Indians/Alaska Natives also exhibit greater rates of sedentary behaviour. Conclusion:. Indigenous groups from Australia, New Zealand, and the United States have a lower life expectancy then their respective non-indigenous counterparts. A higher prevalence of CVD is a major driving force behind this discrepancy. A cluster of modifiable cardio-metabolic risk factors precede CVD, which, in turn, is linked to modifiable lifestyle risk factors

Plan de responsabilidad social empresarial empresa pescamar

En otro enfoque la RSE no tiene una definición en si precisa, en parte por los novedosos relativamente del tema, además aborda una gran variedad de aspectos como el bienestar de los trabajadores, los derechos humanos, la privacidad, la discriminación en el lugar de trabajo, los derechos ambientales, las relaciones con la comunidad, etc. Se halla ligado al desarrollo sostenible, ya que es equivalente a optimizar tres objetivos: equidad social, crecimiento económico y valor ecológico. El desarrollo de productos respetuosos con el medio ambiente es la clave para reducir el impacto negativo en este, es decir, se puede realizar diversas acciones para disminuir el impacto ambiental de las compañías, una de ellas es el uso del MARKETING ECOLÖGICO desde un punto de vista estratégico, y antes la compañía debe adoptar prácticas sociales responsables. Dentro de la sustentabilidad se propone que, de forma voluntaria, las PYME desarrollen programas de RS, y actúen en conjunto con sus grupos de interés (stakeholders) con el fin de comunicar las actuaciones y proyectos que están realicen a través del Marketing Ecológico; bajo esta idea se pueden crear así empresas comprometidas con la sociedad. Concluyendo, por ultimo este estudio permitió analizar la empresa PESCAMAR con el fin de indagar su situación en el ámbito RSE y sustentabilidad, lo que permite visualiza que aún falta mucho por trabajar y por hacer, pero se puede empezar por mejorar aspectos con la generación de acciones que las PYMES pueden llevar a cabo mediante una adecuada planificación.In another approach, RSE does not have a definition. In another approach, CSR does not have a precise definition, partly because of the relative novelty of the topic, it also addresses a wide variety of aspects such as workers' welfare, human rights, privacy , discrimination in the workplace, environmental rights, relations with the community, etc. It is linked to sustainable development, since it is equivalent to optimizing three objectives: social equity, economic growth and ecological value. The development of products that respect the environment is the key to reduce the negative impact on this, that is, you can perform various actions to reduce the environmental impact of companies, one of which is the use of ECOLOGICAL MARKETING from a point of view. Strategic view, and before the company must adopt responsible social practices. Within sustainability, it is proposed that on a voluntary basis, SMEs develop RS programs, and act in conjunction with their stakeholders to communicate the actions and projects that are carried out through Ecological Marketing; Under this idea companies can be created that are committed to society. Finally, this study allowed us to analyze the company PESCAMAR in order to investigate their situation in the field of CSR and sustainability, which allows us to see that there is still a lot to do and work to do, but we can begin to improve aspects with the generation of actions that SMEs can carry out through proper planni

Regulation der Genexpression von MYCN in humanen Neuoblastomzellen durch Transkriptionsfaktoren der E2F-Familie

Seit fast 30 Jahren ist bekannt, dass die Amplifikation und Expression des Onkogens MYCN in Neuroblastomen mit einer sehr ungünstigen Prognose für die Patienten einhergeht. Dennoch liegen die Mechanismen der Genregulation von MYCN weiterhin größtenteils im Dunkeln. Die Präsenz potentieller Bindungsstellen für E2F-Proteine im Promotor des MYCN-Gens sowie Zellkulturexperimente lieferten Hinweise auf eine Rolle der Transkriptionsfaktoren der E2F-Familie in der Regulation der N-myc-Expression. Ziel dieser Arbeit war die Beantwortung der Frage, ob E2F-Proteine notwendig sind, um eine primär hohe Expression von N-myc in Neuroblastomzellen mit Amplifikation des Onkogens aufrechtzuerhalten, und ob sie hinreichend sind, um die Transkription von MYCN in Zellen ohne endogene Expression von N-myc einzuleiten. Durch Überexpression des Tumorsuppressorproteins p16, welches zu einer Inaktivierung endogener E2F-Proteine führt, konnte die MYCN-mRNA-Menge in Neuroblastomzellen deutlich gesenkt werden. Vergleichbare Resultate wurden durch Expression von dominant negativem E2F-1 erzielt. Da in einigen Studien gezeigt werden konnte, dass Myc-Proteine ihrerseits E2F-Gene aktivieren können, nehmen wir an, in aggressiven Neuroblastomen könnte eine positive Rückkopplungsschleife zwischen E2F-Transkriptionsfaktoren auf der einen und N-myc auf der anderen Seite existieren, die die gesteigerte Aktivität des MYCN-Onkogens aufrechterhält. Stabil transfizierte E2F-ER-Fusionsproteine waren jedoch nicht in der Lage, das endogene MYCN-Gen in Neuroblastomzellen ohne Expression von N-myc anzuschalten. E2F-Proteine werden folglich für das volle Ausmaß der starken Expression von N-myc in Neuroblastomen benötigt, sind aber nicht ausreichend, um das Onkogen MYCN in Zellen ohne endogenes N-myc zu aktivieren. In der Zukunft könnte durch Verhinderung der Bindung von E2F-Proteinen an den MYCN-Promotor oder durch gentherapeutische Ansätze, die z.B. mittels viraler Infektion den Signalweg zwischen p16 und E2F rekonstruieren, die Expression von N-myc in Neuroblastomen gesenkt werden, so dass die Aggressivität der Tumore reduziert und die individuelle Prognose der Patienten verbessert werden könnte