Lumbar Spinal Stenosis: Ipsilateral Facet-sparing Unilateral Laminotomy for Bilateral Decompression: Technical Note and Preliminary Results

Microsurgical unilateral laminotomy for bilateral decompression (ULBD) decompresses effectively lumbar stenosis. Whenever low grade degenerative spondylolisthesis, sagittal oriented facet joints, scoliotic deformity, tall disc, and obesity jeopardize postoperative segmental stability, a maximum facet-preserving decompression is desirable. The medialized ULBD (mULBD) aims to preserve the facet joint on the approach side. Sixty-four patients presenting with neurogenic claudication underwent single or multilevel decompression with ULBD or mULBD according to the judgement of the surgeon. The volume of the target facet joints and the dural cross sectional area (CT-DCSA) were measured pre- and postoperatively by an ultra-low-dose CT with a specific software. Forty-three pairs of facet joints were addressed with ULBD and 43 pairs with mULBD. Postoperatively, the mean percentage of the preoperative facet joint volume preserved on the approach side was 70% ± 4% (ULBD) and 88% ± 6% (mULBD); (p<0.001). The mean facet joint volume preserved contraleral to the approach side was 87% ± 6% (ULBD) and 91% ± 6% (mULBD); (p=0.4). The mean postoperative CT-DCSA was 152 ± 30 mm² (ULBD) and 153 ± 26 mm² (mULBD); (p=0.43). The mUBLD decompresses lumbar spinal stenosis effectively as ULBD and preserves better the facet joint on the approach side

Patient demographics and MRI-based measurements predict redundant nerve roots in lumbar spinal stenosis: a retrospective database cohort comparison

Abstract Background Up to 40% of patients diagnosed with lumbar spinal stenosis (LSS) show evidence of redundant nerve roots (RNR) of the cauda equina on their magnetic resonance images (MRI). The etiology of RNR is still unclear. Preoperative evidence of RNR is associated with a worse postsurgical outcome. Consequently, potential predictors of RNR could have a prognostic value. The aim was to test whether patient demographics and MRI-based measurements can predict RNR in LSS patients. Methods In a retrospective database-based cohort study the preoperative data of 300 patients, 150 with (RNR+) and 150 without (RNR-) evidence of RNR on their MRI were analyzed. Three independent researchers performed the MRI reads. Potential predictors were age, gender, body height (BH), length of lumbar spine (LLS), segmental length of lumbar spine (SLLS), lumbar spine alignment deviation (LSAD), relative LLS (rLLS), relative SLLS (rSLLS), number of stenotic levels (LSS-level), and grade of LSS severity (LLS-grade, increasing from A to D). Binomial logistic regression models were performed. Results RNR+ patients were 2.6 years older (p = 0.01). Weak RNR+ predictors were a two-years age increase (OR 1.06; p = 0.02), 3 cm BH decrease (OR 1.09; p = 0.01) and a 5 mm SLLS decrease (OR 1.34; p < 0.001). Strong RNR+ predictors were a 1% rLLS decrease (OR 2.17; p < 0.001), LSS-level ≥ 2 (OR 2.59; p = 0.001), LLS-grade C (OR 5.86; p = 0.02) and LLS-grade D (OR 18.4; p < 0.001). The mean rSLLS of RNR+ patients was 0.6% shorter (p < 0.001; 95% C.I. 0.4 to 0.8) indicating a disproportionate shorter lumbar spine. Conclusions We identified LSS severity grade and LSS levels as the strongest predictors of RNR. In addition to previous studies, we conclude that a shortened lumbar spine by degeneration is involved in the development of RNR

A retrospective analysis of bone mineral status in patients requiring spinal surgery

Abstract Background Impaired bone quality is associated with poor outcome of spinal surgery. The aim of the study was to assess the bone mineral status of patients scheduled to undergo spinal surgery and to report frequencies of bone mineral disorders. Methods We retrospectively analyzed the bone mineral status of 144 patients requiring spinal surgery including bone mineral density by dual-energy X-ray absorptiometry (DXA) as well as laboratory data with serum levels of 25-hydroxyvitamin D (25-OH-D), parathyroid hormone, calcium, bone specific alkaline phosphate, osteocalcin, and gastrin. High-resolution peripheral quantitative computed tomography (HR-pQCT) was additionally performed in a subgroup of 67 patients with T-Score below − 1.5 or history of vertebral fracture. Results Among 144 patients, 126 patients (87.5%) were older than 60 years. Mean age was 70.1 years. 42 patients (29.1%) had suffered from a vertebral compression fracture. 12 previously undiagnosed vertebral deformities were detected in 12 patients by vertebral fracture assessment (VFA). Osteoporosis was present in 39 patients (27.1%) and osteopenia in 63 patients (43.8%). Only 16 patients (11.1%) had received anti-osteoporotic therapy, while 54 patients (37.5%) had an indication for specific anti-osteoporotic therapy but had not received it yet. The majority of patients had inadequate vitamin D status (73.6%) and 34.7% of patients showed secondary hyperparathyroidism as a sign for a significant disturbed calcium homeostasis. In a subgroup of 67 patients, severe vertebral deformities were associated with stronger deficits in bone microarchitecture at the distal radius compared to the distal tibia. Conclusions This study shows that bone metabolism disorders are highly prevalent in elderly patients scheduled for spinal surgery. Vertebral deformities are associated with a predominant deterioration of bone microstructure at the distal radius. As impaired bone quality can compromise surgical outcome, we strongly recommend an evaluation of bone mineral status prior to operation and anti-osteoporotic therapy if necessary

Supplemental material - AO Spine Guideline for the Use of Osteobiologics (AOGO) in Anterior Cervical Discectomy and Fusion for Spinal Degenerative Cases

Supplemental material for AO Spine Guideline for the Use of Osteobiologics (AOGO) in Anterior Cervical Discectomy and Fusion for Spinal Degenerative Cases by Hans-Jörg Meisel, Amit Jain, Yabin Wu, Christopher T. Martin, Juan Pablo Cabrera, Sathish Muthu, Waeel O. Hamouda, Ricardo Rodrigues-Pinto, Jacobus J Arts, Arun-Kumar Viswanadha, Gianluca Vadalà, Pieter-Paul A. Vergroesen, Stipe Ćorluka, Patrick C. Hsieh, Andreas K. Demetriades, Kota Watanabe, John H. Shin, K Daniel Riew, Luca Papavero, Gabriel Liu, Zhuojing Luo, Sashin Ahuja, Tamás Fekete, Atiq Uz Zaman, Mohammad El-Sharkawi, Daisuke Sakai, Samuel K. Cho, Jeffrey Wang, Tim Yoon, Nancy Santesso, and Zorica Buser in Global Spine Journal.</p