124 research outputs found
FSD: An Initial Chinese Dataset for Fake Song Detection
Singing voice synthesis and singing voice conversion have significantly
advanced, revolutionizing musical experiences. However, the rise of "Deepfake
Songs" generated by these technologies raises concerns about authenticity.
Unlike Audio DeepFake Detection (ADD), the field of song deepfake detection
lacks specialized datasets or methods for song authenticity verification. In
this paper, we initially construct a Chinese Fake Song Detection (FSD) dataset
to investigate the field of song deepfake detection. The fake songs in the FSD
dataset are generated by five state-of-the-art singing voice synthesis and
singing voice conversion methods. Our initial experiments on FSD revealed the
ineffectiveness of existing speech-trained ADD models for the task of song
deepFake detection. Thus, we employ the FSD dataset for the training of ADD
models. We subsequently evaluate these models under two scenarios: one with the
original songs and another with separated vocal tracks. Experiment results show
that song-trained ADD models exhibit a 38.58% reduction in average equal error
rate compared to speech-trained ADD models on the FSD test set.Comment: Submitted to ICASSP 202
Leptin deficiency in CD8+ T cells ameliorates non-segmental vitiligo by reducing interferon-γ and Granzyme B
BackgroundVitiligo is an autoimmune skin disease mainly mediated by CD8+ T cells, which affects about 0.1%-2% population of the world. Leptin plays a critical role in regulating the activation of CD8+ T cells. However, the effect of Leptin on vitiligo remains unclear.ObjectivesTo explore the effect of leptin on CD8+ T cells and its influence on vitiligo.MethodsRNA sequencing and Quantitative Real-time PCR (RT-qPCR) were used to explore the differentially expressed genes. Immunofluorescence staining was performed on skin lesions. Leptin in serum was detected by enzyme linked immunosorbent assay (ELISA). The peripheral blood mononuclear cells were detected by flow cytometry after leptin stimulation for 72 hours. A vitiligo model was established by monobenzone on Leptin KO mice.Results557 differentially expressed genes were found, including 154 up-regulated and 403 down-regulated genes. Lipid metabolism pathways showed a close relationship to the pathogenesis of vitiligo, especially the PPAR signaling pathway. RT-qPCR (p = 0.013) and immunofluorescence staining (p = 0.0053) verified that LEPR expressed significantly higher in vitiligo. The serum leptin level of vitiligo patients was significantly lower than that of healthy controls (p = 0.0245). The interferon-γ subset of CD8+LEPR+ T cells from vitiligo patients was significantly higher (p = 0.0189). The protein level of interferon-γ was significantly increased after leptin stimulation in vitro (p = 0.0217). In mice, Leptin deficiency resulted in less severe hair depigmentation. Leptin deficiency also resulted in significantly lower expressed vitiligo-related genes, such as Cxcl9 (p = 0.0497), Gzmb (p < 0.001), Ifng (p = 0.0159), and Mx1 (p < 0.001) after modeling.ConclusionLeptin could promote the progression of vitiligo by enhancing the cytotoxic function of CD8+ T cells. Leptin may become a new target for vitiligo treatment
Search for the Lepton Flavor Violation Process at BESIII
We search for the lepton-flavor-violating decay of the into an
electron and a muon using events
collected with the BESIII detector at the BEPCII collider. Four candidate
events are found in the signal region, consistent with background expectations.
An upper limit on the branching fraction of (90% C.L.) is obtained
Search for Baryonic Decays of \psi(3770) and \psi(4040)
By analyzing data samples of 2.9 fb^{-1} collected at \sqrt s=3.773 GeV, 482
pb^{-1} collected at \sqrt s=4.009 GeV and 67 pb^{-1} collected at \sqrt
s=3.542, 3.554, 3.561, 3.600 and 3.650 GeV with the BESIII detector at the
BEPCII storage ring, we search for \psi(3770) and \psi(4040) decay to baryonic
final states, including \Lambda\bar\Lambda\pi^+\pi^-, \Lambda \bar\Lambda\pi^0,
\Lambda\bar\Lambda\eta, \Sigma^+ \bar\Sigma^-, \Sigma^0 \bar\Sigma^0,
\Xi^-\bar\Xi^+ and \Xi^0\bar\Xi^0 decays. None are observed, and upper limits
are set at the 90% confidence level.Comment: 9 pages, 3 figure
Observation of a charged charmoniumlike structure in at GeV
We study the process at a
center-of-mass energy of 4.26GeV using a 827pb data sample obtained with
the BESIII detector at the Beijing Electron Positron Collider. Based on a
partial reconstruction technique, the Born cross section is measured to be
pb. We observe a structure near the
threshold in the recoil mass spectrum, which we denote as the
. The measured mass and width of the structure are
MeV/c and MeV, respectively. Its
production ratio is determined to be . The first uncertainties
are statistical and the second are systematic.Comment: 7 pages, 4 figures, 1 table; version accepted to be published in PR
An inductor-less broadband design technique for transimpedance amplifiers
An inductor-less bandwidth enhancement technique for transimpedance amplifiers is proposed in this paper, which uses a single capacitor to realize negative capacitance, capacitive source degeneration and capacitive
peaking at the same time. Based on this technique, a broadband
transimpedance amplifier is designed and simulated in 0.18μm
RFCMOS technology. The simulation results show a bandwidth enhancement ratio of 2.5 is achieved without any inductor employed. The proposed TIA circuit is suitable for 10Gbit/s
optical communications and presents the advantages of much less chip area consumption, low-cost and easy of design comparing to inductor based designs.Published versio
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