12,155 research outputs found
Simulation of anyonic statistics and its topological path independence using a 7-qubit quantum simulator
Anyons, quasiparticles living in two-dimensional spaces with exotic exchange
statistics, can serve as the fundamental units for fault-tolerant quantum
computation. However, experimentally demonstrating anyonic statistics is a
challenge due to the technical limitations of current experimental platforms.
Here, we take a state perpetration approach to mimic anyons in the Kitaev
lattice model using a 7-qubit nuclear magnetic resonance quantum simulator.
Anyons are created by dynamically preparing the ground and excited states of
the 7-qubit Kitaev lattice model, and are subsequently braided along two
distinct, but topologically equivalent, paths. We observe that the phase
acquired by the anyons is independent of the path, and coincides with the ideal
theoretical predictions when decoherence and implementation errors are taken
into account. As the first demonstration of the topological path independence
of anyons, our experiment helps to study and exploit the anyonic properties
towards the goal of building a topological quantum computer.Comment: 12 pages and 9 figures. All comments are welcome
The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism
Recent evidence suggests that PPARγ agonists may promote anti-tumor immunity. We show that immunogenic PDV cutaneous squamous cell carcinoma (CSCC) tumors are rejected when injected intradermally at a low cell number (1 × 106) into immune competent syngeneic hosts, but not immune deficient mice. At higher cell numbers (5 × 106 PDV cells), progressively growing tumors were established in 14 of 15 vehicle treated mice while treatment of mice with the PPARγ agonist rosiglitazone resulted in increased tumor rejection (5 of 14 tumors), a significant decrease in PDV tumor size, and a significant decrease in tumor cell Ki67 labeling. Rosiglitazone treatment had no effect on tumor rejection, tumor volume or PDV tumor cell proliferation in immune deficient NOD.CB17-PrkdcSCID/J mice. Rosiglitazone treatment also promoted an increase in tumor infiltrating CD3+ T-cells at both early and late time points. In contrast, rosiglitazone treatment had no significant effect on myeloid cells expressing either CD11b or Gr-1 but suppressed a late accumulation of myeloid cells expressing both CD11b and Gr-1, suggesting a potential role for CD11b+Gr-1+ myeloid cells in the late anti-tumor immune response. Overall, our data provides evidence that the PPARγ agonist rosiglitazone promotes immune-mediated anti-neoplastic activity against tumors derived from this immunogenic CSCC cell line
Chiral Quantum Walks
Given its importance to many other areas of physics, from condensed matter
physics to thermodynamics, time-reversal symmetry has had relatively little
influence on quantum information science. Here we develop a network-based
picture of time-reversal theory, classifying Hamiltonians and quantum circuits
as time-symmetric or not in terms of the elements and geometries of their
underlying networks. Many of the typical circuits of quantum information
science are found to exhibit time-asymmetry. Moreover, we show that
time-asymmetry in circuits can be controlled using local gates only, and can
simulate time-asymmetry in Hamiltonian evolution. We experimentally implement a
fundamental example in which controlled time-reversal asymmetry in a
palindromic quantum circuit leads to near-perfect transport. Our results pave
the way for using time-symmetry breaking to control coherent transport, and
imply that time-asymmetry represents an omnipresent yet poorly understood
effect in quantum information science.Comment: 9 pages, 4 figures, REVTeX 4.1 - published versio
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