450 research outputs found
A Spatiotemporal-chaos-based Encryption Having Overall Properties Considerably Better Than Advanced Encryption Standard
Spatiotemporal chaos of a two-dimensional one-way coupled map lattice is used
for chaotic cryptography. The chaotic outputs of many space units are used for
encryption simultaneously. This system shows satisfactory cryptographic
properties of high security; fast encryption (decryption) speed; and robustness
against noise disturbances in communication channel. The overall features of
this spatiotemporal-chaos-based cryptosystem are better than chaotic
cryptosystems known so far, and also than currently used conventional
cryptosystems, such as the Advanced Encryption Standard (AES).Comment: 11 pages, 3 figure
The resilience of interdependent transportation networks under targeted attack
Modern world builds on the resilience of interdependent infrastructures
characterized as complex networks. Recently, a framework for analysis of
interdependent networks has been developed to explain the mechanism of
resilience in interdependent networks. Here we extend this interdependent
network model by considering flows in the networks and study the system's
resilience under different attack strategies. In our model, nodes may fail due
to either overload or loss of interdependency. Under the interaction between
these two failure mechanisms, it is shown that interdependent scale-free
networks show extreme vulnerability. The resilience of interdependent SF
networks is found in our simulation much smaller than single SF network or
interdependent SF networks without flows.Comment: 5 pages, 4 figure
The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure:Implications for function
FcγRI (CD64) is the only high-affinity Fcγ receptor found on monocytes, macrophages, eosinophils, neutrophils and dendritic cells. It binds immunoglobulin G (IgG) antibody-antigen complexes at its Fc region to trigger key immune responses. CD64 contains three immunoglobulin-fold extracellular domains (D1, D2 and D3) and a membrane-spanning region. Despite the importance of CD64, no solution structure for this is known to date. To investigate this, we used analytical ultracentrifugation, small-angle X-ray scattering, and atomistic modelling. Analytical ultracentrifugation revealed that CD64 was monomeric with a sedimentation coefficient s020,w of 2.53 S, together with some dimer. Small-angle X-ray scattering showed that its radius of gyration RG was 3.3–3.4 nm and increased at higher concentrations to indicate low dimerization. Monte Carlo modelling implemented in the SASSIE-web package generated 279,162 physically-realistic trial CD64 structures. From these, the scattering best-fit models at the lowest measured concentrations that minimised dimers revealed that the D1, D2 and D3 domains were structurally similar to those seen in three CD64 crystal structures, but showed previously unreported flexibility between D1, D2 and D3. Despite the limitations of the scattering data, the superimposition of the CD64 solution structures onto crystal structures of the IgG Fc-CD64 complex showed that the CD64 domains do not sterically clash with the IgG Fc region, i.e. the solution structure of CD64 was sufficiently compact to allow IgG to bind to its high-affinity Fcγ receptor. This improved understanding may result in novel approaches to inhibit CD64 function, and opens the way for the solution study of the full-length CD64-IgG complex.</p
The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function
FcγRI (CD64) is the only high-affinity Fcγ receptor found on monocytes, macrophages, eosinophils, neutrophils and dendritic cells. It binds immunoglobulin G (IgG) antibody-antigen complexes at its Fc region to trigger key immune responses. CD64 contains three immunoglobulin-fold extracellular domains (D1, D2 and D3) and a membrane-spanning region. Despite the importance of CD64, no solution structure for this is known to date. To investigate this, we used analytical ultracentrifugation, small-angle X-ray scattering, and atomistic modelling. Analytical ultracentrifugation revealed that CD64 was monomeric with a sedimentation coefficient s020,w of 2.53 S, together with some dimer. Small-angle X-ray scattering showed that its radius of gyration RG was 3.3–3.4 nm and increased at higher concentrations to indicate low dimerization. Monte Carlo modelling implemented in the SASSIE-web package generated 279,162 physically-realistic trial CD64 structures. From these, the scattering best-fit models at the lowest measured concentrations that minimised dimers revealed that the D1, D2 and D3 domains were structurally similar to those seen in three CD64 crystal structures, but showed previously unreported flexibility between D1, D2 and D3. Despite the limitations of the scattering data, the superimposition of the CD64 solution structures onto crystal structures of the IgG Fc-CD64 complex showed that the CD64 domains do not sterically clash with the IgG Fc region, i.e. the solution structure of CD64 was sufficiently compact to allow IgG to bind to its high-affinity Fcγ receptor. This improved understanding may result in novel approaches to inhibit CD64 function, and opens the way for the solution study of the full-length CD64-IgG complex
S3: Social-network Simulation System with Large Language Model-Empowered Agents
Social network simulation plays a crucial role in addressing various
challenges within social science. It offers extensive applications such as
state prediction, phenomena explanation, and policy-making support, among
others. In this work, we harness the formidable human-like capabilities
exhibited by large language models (LLMs) in sensing, reasoning, and behaving,
and utilize these qualities to construct the S system (short for
ocial network imulation ystem). Adhering to
the widely employed agent-based simulation paradigm, we employ prompt
engineering and prompt tuning techniques to ensure that the agent's behavior
closely emulates that of a genuine human within the social network.
Specifically, we simulate three pivotal aspects: emotion, attitude, and
interaction behaviors. By endowing the agent in the system with the ability to
perceive the informational environment and emulate human actions, we observe
the emergence of population-level phenomena, including the propagation of
information, attitudes, and emotions. We conduct an evaluation encompassing two
levels of simulation, employing real-world social network data. Encouragingly,
the results demonstrate promising accuracy. This work represents an initial
step in the realm of social network simulation empowered by LLM-based agents.
We anticipate that our endeavors will serve as a source of inspiration for the
development of simulation systems within, but not limited to, social science
Correlation-driven eightfold magnetic anisotropy in a two-dimensional oxide monolayer.
Engineering magnetic anisotropy in two-dimensional systems has enormous scientific and technological implications. The uniaxial anisotropy universally exhibited by two-dimensional magnets has only two stable spin directions, demanding 180° spin switching between states. We demonstrate a previously unobserved eightfold anisotropy in magnetic SrRuO3 monolayers by inducing a spin reorientation in (SrRuO3)1/(SrTiO3) N superlattices, in which the magnetic easy axis of Ru spins is transformed from uniaxial 〈001〉 direction (N < 3) to eightfold 〈111〉 directions (N ≥ 3). This eightfold anisotropy enables 71° and 109° spin switching in SrRuO3 monolayers, analogous to 71° and 109° polarization switching in ferroelectric BiFeO3. First-principle calculations reveal that increasing the SrTiO3 layer thickness induces an emergent correlation-driven orbital ordering, tuning spin-orbit interactions and reorienting the SrRuO3 monolayer easy axis. Our work demonstrates that correlation effects can be exploited to substantially change spin-orbit interactions, stabilizing unprecedented properties in two-dimensional magnets and opening rich opportunities for low-power, multistate device applications
Ring-Like Solitons in Plasmonic Fiber Waveguide Composed of Metal-Dielectric Multilayers
We design a plasmonic fiber waveguide (PFW) composed of coaxial cylindrical
metal-dielectric multilayers in nanoscale, and constitute the corresponding
dynamical equations describing the modes of propagation in the PFW with the
Kerr nonlinearity in the dielectric layers. The physics is connected to the
discrete matrix nonlinear Schr\"{o}dinger equations, from which the highly
confined ring-like solitons in scale of subwavelength are found both for the
visible light and the near-infrared light in the self-defocusing condition.
Moreover, the confinement could be further improved when increasing the
intensity of the input light due to the cylindrical symmetry of the PFW, which
means both the width and the radius of the ring are reduced.Comment: 4 figures, submitte
- …