The British Geological Survey's new Geomagnetic Data Web Service

Increasing demand within the geomagnetism community for high quality real-time or near-real-time observatory data means there is a requirement for data producers to have a robust and scalable data processing infrastructure capable of delivering geomagnetic data products over the Internet in a variety of formats. We describe a new software system, developed at BGS, which will allow access to our geomagnetic data products both within our organisation's intranet and over the Internet. We demonstrate how the system is designed to afford easy access to the data by a wide range of software clients and allow rapid development of software utilizing our observatory data

Can remote STI/HIV testing and eClinical Care be compatible with robust public health surveillance?

In this paper we outline the current data capture systems for human immunodeficiency virus (HIV) and sexually transmitted infection (STI) surveillance used by Public Health England (PHE), and how these will be affected by the introduction of novel testing platforms and changing patient pathways. We outline the Chlamydia Online Clinical Care Pathway (COCCP), developed as part of the Electronic Self-Testing for Sexually Transmitted Infections (eSTI(2)) Consortium, which ensures that surveillance data continue to be routinely collected and transmitted to PHE. We conclude that both novel diagnostic testing platforms and established data capture systems must be adaptable to ensure continued robust public health surveillance

Optical and Infrared Spectroscopy

Contains research objectives, summary of research and reports on four research projects.Joint Services Electronics Programs (U. S. Army, U.S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E)National Aeronautics and Space Administration (Grant NGR-22-009-237)U. S. Air Force Cambridge Research Laboratories Contract AF 19(628)-606

Future of technology in NERC data models and informatics: outputs from InformaTEC

The ‘Big Data’ paradigm will revolutionize understanding of the natural environment. New technologies are revolutionizing our ability to measure, model, understand and make robust, evidence-based predictions at increasingly spatial and temporal resolutions. Realising this potential will require reengineering of environmental sciences in the observation infrastructure, in data management and processing, and in the culture of environmental sciences. Collectively these will deliver vibrant, integrated research communities. Manipulating such enormous data streams requires a new data infrastructure underpinned by four technologies. Pervasive environmental sensor networks will continuously measure suites of environmental parameters and transmit these wirelessly to scientists, regulators and modellers in real time. Integrated environmental modelling will process data, streamed from sensor networks, using components synthesizing natural systems developed by domain experts, each of which will be linked at runtime to other expert developed components. Semantic interoperability will facilitate cross-disciplinary working, as has already happened within the biosciences so that data items can be exchanged with unambiguous, shared meaning. Cloud computing will revolutionize data processing allowing scalable computing close to observations on an as-needed basis. Leveraging the full potential of these technologies requires a major culture change in the environmental sciences where national and continental scale observatories of sensors networks become basic scientific tools

The South West Area Mesothelioma and Pemetrexed trial - A multi-centre prospective observational study evaluating novel markers of chemotherapy response and prognostication

Background:Robust markers that predict prognosis and detect early treatment response in malignant pleural mesothelioma (MPM) would enhance patient care.Methods:Consecutive patients with MPM who were considered fit for first-line chemotherapy were prospectively recruited. Patients of similar performance status opting for best supportive care were included as a comparator group. Baseline and interval CT, PET-CT and serum markers (mesothelin, fibulin-3 and neutrophil–lymphocyte ratio (NLR)) were obtained, and patients followed up for a minimum 12 months.Findings:Seventy-three patients were recruited (58 chemotherapy/15 comparator arm). Baseline TGV (total glycolytic volume on PET-CT) was an independent predictor of worse overall survival (OS) (P=0.001). Change in interval TGV(baseline/after two cycles of chemotherapy) did not predict OS or chemotherapy response on CT. Baseline NL

Developing a framework for the analysis of power through depotentia

Stakeholder participation in tourism policy-making is usually perceived as providing a means of empowerment. However participatory processes drawing upon stakeholders from traditionally empowered backgrounds may provide the means of removing empowerment from stakeholders. Such an outcome would be in contradiction to the claims that participatory processes improve both inclusivity and sustainability. In order to form an understanding of the sources through which empowerment may be removed, an analytical perspective has been developed deriving from Lukes�s views of power dating from 1974. This perspective considers the concept of depotentia as the removal of �power to� without speculating upon the underlying intent and also provides for the multidimensionality of power to be examined within a single study. The application of this analytical perspective has been tested upon findings of the government-commissioned report of the Countryside and Community Research Unit in 2005. The survey and report investigated the progress of Local Access Forums in England created in response to the Countryside and Rights of Way Act 2000. Consideration of the data from this perspective permits the classification of individual sources of depotentia which can each be addressed and potentially enable stakeholder groups to reverse loss of empowerment where it has occurred

Prospects for local co-governance

British local authorities and their partners are increasingly developing new ways of working together with local communities. The nature of this co-working, however, is complex, multi-faceted and little understood. This article argues for greater clarity of thinking on the topic, by analysing this co-working as a form of political co-governance, and drawing attention in particular to issues of scale and democracy. Using evidence from a study of 43 local authority areas, 16 authorities are identified where co-governance is practised, following three main types of approach: service-influencing, service-delivering and parish council developing. It is concluded that strengthening political co-governance is essential for a healthy democracy

Effective Vortex Pinning in MgB2 thin films

We discuss pinning properties of MgB2 thin films grown by pulsed-laser deposition (PLD) and by electron-beam (EB) evaporation. Two mechanisms are identified that contribute most effectively to the pinning of vortices in randomly oriented films. The EB process produces low defected crystallites with small grain size providing enhanced pinning at grain boundaries without degradation of Tc. The PLD process produces films with structural disorder on a scale less that the coherence length that further improves pinning, but also depresses Tc