THE DEVELOPMENT OF A FRAMEWORK FOR THE USE OF INFORMATION AND COMMUNICATION TECHNOLOGY IN THE CLASSROOM

Published ThesisThe aim of this study was to explore the development of a framework for the use of Information and Communication Technology in the classroom. It was clear from the study that teachers lack Information and Communication Technology (ICT) capability, and should therefore be trained and retrained. While they are expected to produce quality education, they are also expected to receive training which is a time-consuming exercise and often makes teachers want to give up on the implementation of ICT in the classroom. If teachers were to use ICT in the classroom, it would change the passive role of the learners in which they merely receive knowledge to a more active role where they construct their own knowledge. In addition, teachers would have the opportunity to connect with experts, and have access to global resources. Teachers should be motivated to use ICT to improve the quality of their teaching. This, together with proper ICT skills, would ensure the effective use of ICT. To ascertain the effective use of ICT by teachers, research was conducted in ten secondary schools in Bloemfontein. A random sample of 30 secondary school teachers was drawn from ten schools. A mixed methods approach was used to the collect data, i.e. qualitative (questionnaires) and qualitative (interviews). Questionnaires were administered to the participants and were then followed by unstructured interviews. The research participants were selected randomly from the study population in an unbiased manner to produce quantifiable, reliable data. Mix methods designs provide advantages when a researcher is exploring complex research questions. The findings of this study revealed that teachers have a positive attitude towards the use of ICT, and that it enables better teaching standards and educational outcomes. Teachers also have barriers that hinder them from using ICT in the classroom

Gender differences in barriers to alcohol and other drug treatment in Cape Town, South Africa

Objective: The study aimed to identify gender differences in barriers to alcohol and other drug (AOD) treatment use among disadvantaged communities in Cape Town, South Africa. The Behavioral Model of Health Services Utilization was used as an analytic framework. Method: A case-control design was used to compare 434 individuals with AOD problems from disadvantaged communities who had accessed treatment with 555 controls who had not accessed treatment on a range of variables. Logistic regression procedures were employed to examine the unique profile of variables associated with treatment utilization for male and female participants. Results: Few gender differences emerged in terms of the pattern of variables associated with AOD treatment use. Greater awareness of treatment options and fewer geographic access and affordability barriers were strongly associated with an increased likelihood of AOD treatment use for both men and women from disadvantaged communities. However, while similar types of barriers to treatment were reported by men and women, these barriers had a greater impact on treatment utilization for women compared to men. Conclusion: Compared to men, women from disadvantaged communities in South Africa do not have equal access to AOD treatment. Recommendations on how to reduce these barriers and ways to improve AOD treatment use among women from disadvantaged communities in South Africa are provided.Keywords: Health care quality; Access and evaluation; Gender; Substance abuse treatment centres; South Afric

Spirometry of healthy adult South African men

Aim. To detennine normative spirometric values for black and white South African men.Methods. A population of 796 bank personnel were subjected to spirometry and anthropometric measurements. An exhaustive questionnaire and radiographic screening process was used to identify a healthy population. Spirometry was performed using two calibrated instruments, a sleeve sealed piston spirometer (Autolink) and a bellows spirometer (Vitalograph). The methodological guidelines of the American Thoracic Society were observed. In the regression analysis Mallow's CP statistic was used to identify the best prediction models.Results. Compelling evidence was found in support of incorporating sitting height in prediction equations. For the Autolink studies the prediction equations (based on age, slanding height and weight) for forced vital capacity (FVC) (litres) were as follows: blacks: 0.053 height- 0.030 age 3.54; and whites: 0.056 height - 0.038 age - 3.07; for forced expiratory volume in the 1st second (FEV,) (litres) blacks: 0.038 height- 0.032 age - 1.18; and whites: 0.042 height- 0.038 age - 1.45. For the VitaJograph the equations were: FVC: blacks 0.048 height - 0.024 age 3.08 L; whites 0.056 height- 0.031 age - 3.42; FEV,: blacks 0.029 height - 0.027 age - 0.535; whites 0.042 height- 0.036 age - 1.84.Conclusion. The VitaJograph yielded significantly lower values than the Autolink for FVC measurements despite absolute consistency in methods. In view of the fact that the present study was conducted on healthy men, free from noxious industrial exposure, using state-of-the-art methods, these prediction equations may be regarded as the definitive norms for adult South African males

The use of VTE prophylaxis in relation to patient risk profiling(TUNE-IN) Wave 2 Study

KMBackground: The TUNE-IN (The Use of VTE prophylaxis in relatioN to patiEnt risk profiling) study evaluated venous thromboembolism (VTE) risk assessment and prophylaxis in private medical and surgical inpatients in Gauteng Province, South Africa. The study concluded that of the 608 patients enrolled, 54.1% were clinically evaluated to be at risk for VTE. A VTE risk assessment model (RAM), the Caprini score, increased the rate to 74.6%. Objectives: TUNE-IN Wave 2, an extension of TUNE-IN, was conducted on a national level including the public sector, focusing on surgical inpatients. Methods. The study was a national, prospective, non-interventional, multisite, epidemiological disease registry enrolling 453 surgical inpatients. The perceived clinical VTE risk, VTE risk score on Caprini RAM, VTE prophylaxis and clinical details were documented during a baseline visit. A bleeding risk score was provided. Results: Of the cohort, 269 patients (59.4%) were assessed to be at risk for VTE before applying the RAM. All patients (100%), however, were at risk on the RAM score. Early mobilisation and assessment of the VTE risk as low were the most frequent reasons for non-prescription of prophylaxis. Only 15 patients in the private and 2 in the public sector were assessed as having a bleeding risk. Chemoprophylaxis differed between the healthcare sectors, with low-molecular-weight heparin predominating in the private sector and unfractionated heparin being prescribed only in the public sector. Conclusion: VTE risk assessment and prophylaxis need to improve in both the public and the private sectors. A formal RAM will improve identification of patients at risk of VTE

The influence of yoga therapy on anxiety

The stressful lifestyles that accompany modern living generate levels of anxiety that become a major concern in society. Psychopharmacological medication and psychotherapy for anxiety is expensive for government health departments as well as for individual consumers. Although the value of yoga as a beneficial and cost effective therapy for anxiety has long been advocated, there have been very few well designed scientific studies in this regard. Therefore the aim of this research was to evaluate the effectiveness of yoga therapy on anxiety perceptions and experiences. The research hypothesis that yoga could decrease such anxiety was investigated by comparing two groups, an experimental group of 18 participants that practised yoga and a control group of 19 participants that did not practise yoga, over a duration of three months, The research design included quantitative and qualitative research methods. Quantitative results from the Beck Anxiety Inventory (BAI) indicated that, although regular yoga therapy was associated with significant decreases in anxiety perceptions over time, these changes were not significant when compared with the control group. Therefore, no causative inferences can be made. Qualitative findings from thematic content analysis of participants’ experiences suggested meaningful relief from anxiety over time, especially with regard to such themes as physicality, contentment, relaxation, breath control, mindfulness, transcendence and spirituality. Although further randomised controlled studies with larger samples are needed, this research provided some systematic evidence for yoga therapy as a significant and relatively cost effective intervention for anxiety reduction. Key Words: Yoga, therapy, anxiety, stress

Thrombotic disorders (part 1)

Thromboembolic conditions are the leading cause of mortality, estimated to account for 1 in 4 deaths worldwide in 2010. Over time, the incidence and mortality rates of these conditions have improved in developed countries, but are increasing in developing countries. The haemostatic system comprises 6 main components, i.e. (i) platelets; (ii) vascular endothelium; (iii) coagulation proteins; (iv) natural anticoagulants; (v) the fibrinolytic system; and (vi) natural antifibrinolytic factors. A delicate balance exists between procoagulant and anticoagulant factors within the vascular system. Numerous acquired or inherited conditions may tip the balance either way, i.e. towards a prothrombotic or prohaemorrhagic state. In this issue of CME, the first of a 2-part series on thrombophilic disorders, the subject of discussion is on inherited varieties that the general practitioner is likely to encounter. This review is primarily based on venous thrombosis

South African Guidelines Excellence (SAGE): Adopt, adapt, or contextualise?

Clinical practice guideline (CPG) activities must be planned carefully for efficient use of available resources and evidence-based implementation. De novo development of CPGs may sometimes ‘recreate the wheel’ and delay implementation. Three innovative alternatives to de novo CPG development (adopt, contextualise or adapt) are outlined, which have greater potential than de novo development to best use the limited available resources, personnel and time in settings such as South Africa

Inherited bleeding disorders

Abnormal bleeding is a common clinical presentation in general practice, and a rational approach to this problem is therefore required. Investigation of a suspected bleeding disorder necessitates a comprehensive history, thorough physical examination and systematic laboratory work-up. Inherited bleeding disorders (IBDs) typically manifest in childhood, but may present later in life after a haemostatic challenge (such as trauma, surgery, tooth extraction). This two-part CME series is intended to provide insight to the medical practitioner on the clinical spectrum, diagnosis and management of bleeding disorders. Bleeding due to inherited disorders is the subject of discussion in part 1 (current issue), and in part 2 (forthcoming issue) the focus is on bleeding from acquired causes. Patients diagnosed with an IBD should ideally be referred to a dedicated tertiary healthcare facility, e.g. haemophilia centre, for management and follow-up

Experimental Validation of a Fundamental Model for PCR Efficiency

Recently a theoretical analysis of PCR efficiency has been published by Booth et al., (2010). The PCR yield is the product of three efficiencies: (i) the annealing efficiency is the fraction of templates that form binary complexes with primers during annealing, (ii)the polymerase binding efficiency is the fraction of binary complexes that bind to polymerase to form ternary complexes and (iii)the elongation efficiency is the fraction of ternary complexes that extend fully. Yield is controlled by the smallest of the three efficiencies and control could shift from one type of efficiency to another over the course of a PCR experiment. Experiments have been designed that are specifically controlled by each one of the efficiencies and the results are consistent with the mathematical model. The experimental data has also been used to quantify six key parameters of the theoretical model. An important application of the fully characterized model is to calculate initial template concentration from real-time PCR data. Given the PCR protocol, the midpoint cycle number (where the template concentration is half that of the final concentration) can be theoretically determined and graphed for a variety of initial DNA concentrations. Real-time results can be used to calculate the midpoint cycle number and consequently the initial DNA concentration, using this graph. The application becomes particularly simple if a conservative PCR protocol is followed where only the annealing efficiency is controlling

Efficiency of the Polymerase Chain Reaction

The polymerase chain reaction (PCR) has found wide application in biochemistry and molecular biology such as gene expression studies, mutation detection, forensic analysis and pathogen detection. Increasingly quantitative real time PCR is used to assess copy numbers from overall yield. In this study the yield is analyzed as a function of several processes: (1) thermal damage of the template and polymerase occurs during the denaturing step, (2) competition exists between primers and templates to either anneal or form dsDNA, (3) polymerase binding to annealed products (primer/ssDNA) to form ternary complexes and (4) extension of ternary complexes. Explicit expressions are provided for the efficiency of each process, therefore reaction conditions can be directly linked to the overall yield. Examples are provided where different processes play the yield-limiting role. The analysis will give researchers a unique understanding of the factors that control the reaction and will aid in the interpretation of experimental results