110 research outputs found

    Performance of Sentry-Glas-laminated metal-reinforced glass beams at 23, -20, and 60 ºC

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    Keywords: 1=reinforced 2=beam 3=SentryGlas 4=interlayer 5=temperature 6=redundancy. Abstract To validate the novel concept of laminating a metal reinforcement to a glass beam using a SentryGlas (SG) interlayer, a series of bending tests has been performed at 23, -20 and 60°C on 1.5 m SG-laminated metal-reinforced glass beams. The beams consisted of three glass layers with a stainless steel box section laminated in between the glass at the lower edge. The test results showed high redundancy of the beam specimens at all tested temperature levels. However, the specific response of the beam specimens varied at different temperature levels. At 23°C the beam specimens showed the highest residual strength, whereas the residual strength was reduced at both -20 and 60°C. This difference in response was caused by a difference in glass cracking behaviour and the occurrence of plastic hinges in the beams. These plastic hinges limited the residual strength of the beam and probably originated from a more brittle response of the SG at -20°C and a lower metal-to-glass bond strength of the SG at 60°C. Since the SG-laminated metal-reinforced glass beams showed promising results, future research at TU Delft will further explore the possibilities of this concept

    Antimigraine medication use and associated health care costs in employed patients

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    Migraine is under diagnosed and suboptimally treated in the majority of patients, and also associated with decreased productivity in employees. The objective of this retrospective study is to assess the antimigraine medication use and associated resource utilization in employed patients. Patients with primary diagnosis of migraine or receiving antimigraine prescription drugs were identified from an employer-sponsored health insurance plan in 2010. Medical utilization and health care costs were determined for the year of 2010. Generalized linear regression was applied to evaluate the association between health care costs and the use of antimigraine medications by controlling covariates. Of 465 patients meeting the study criteria, nearly 30% that had migraine diagnosis were prescribed antimigraine medications, and 20% that had migraine diagnosis were not prescribed antimigraine medications. The remaining 50% were prescribed antimigraine medications but did not have migraine diagnosis. Patients with antimigraine medication prescriptions showed lower frequency of emergency department visits than those without antimigraine medication prescriptions. Regression models indicated an increase in migraine-related health care costs by 86% but decreases in all-cause medical costs and total health care costs by 42 and 26%, respectively, in the antimigraine medication use group after adjusting for covariates. Employed patients experienced inadequate pharmacotherapy for migraine treatment. After controlling for covariates, antimigraine prescription drug use was associated with lower total medical utilization and health care costs. Further studies should investigate patient self-reported care and needs to manage headache and develop effective intervention to improve patient quality of life and productivity

    Recognition and diagnosis of sleep disorders in Parkinson's disease

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    Contains fulltext : 109296.pdf (publisher's version ) (Open Access)Sleep disturbances are among the most frequent and incapacitating non-motor symptoms of Parkinson's disease (PD), and are increasingly recognized as an important determinant of impaired quality of life. Here we review several recent developments regarding the recognition and diagnosis of sleep disorders in PD. In addition, we provide a practical and easily applicable approach to the diagnostic process as a basis for tailored therapeutic interventions. This includes a stepwise scheme that guides the clinical interview and subsequent ancillary investigations. In this scheme, the various possible sleep disorders are arranged not in order of prevalence, but in a 'differential diagnostic' order. We also provide recommendations for the use of sleep registrations such as polysomnography. Furthermore, we point out when a sleep specialist could be consulted to provide additional diagnostic and therapeutic input. This structured approach facilitates early detection of sleep disturbances in PD, so treatment can be initiated promptly

    Nature’s nations: the shared conservation history of Canada and the USA

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    Historians often study the history of conservation within the confines of national borders, concentrating on the bureaucratic and political manifestations of policy within individual governments. Even studies of the popular expression of conservationist ideas are generally limited to the national or sub-national (province, state, etc.) scale. This paper suggests that conservationist discourse, policy and practice in Canada and the USA were the products of a significant cross-border movement of ideas and initiatives derived from common European sources. In addition, the historical development of common approaches to conservation in North America suggests, contrary to common assumptions, that Canada did not always lag behind the USA in terms of policy innovation. The basic tenets of conservation (i.e. state control over resource, class-based disdain for subsistence hunters and utilitarian approaches to resource management) have instead developed at similar time periods and along parallel ideological paths in Canada and the USA

    Numerical analyses of the effect of SG-interlayer shear stiffness on the structural performance of reinforced glass beams

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    This paper focuses on the numerical modelling of SentryGlas-laminated reinforced glass beams. In these beams, which have been experimentally investigated in preceding research, a stainless steel reinforcement section is laminated at the inner recessed edge of a triple-layer glass beam by means of SentryGlas (SG) interlayer sheets. The current contribution numerically investigates the effect of the SG-interlayer shear stiffness on the overall structural response of the beams. This is done by means of a 3D finite element model in which the individual glass layers, the SG-interlayers and the reinforcement are incorporated. In the model, the glass parts are allowed to crack, but all other parts are assumed linear elastic throughout the analyses. By changing the shear modulus of the SG-interlayer in multiple analyses, its contribution to the overall structural performance of the beams – especially at the post-breakage stage – is investigated. From the results of the analyses it is observed that the residual load-bearing capacity, i.e. the load-bearing capacity after glass fracture, increases with an increasing shear modulus of the SG-interlayer. Furthermore, the load-displacement response from the numerical model is predicting experimental observations very well. However, the crack pattern resulting from the numerical model is not matching the experimental observations. Further studies are thus needed to fully understand the mechanisms involved in the structural behaviour of SGlaminated reinforced glass beams
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