KOMUNITAS GASTROPODA PADA PERAIRAN DUSUN ANAUNI DESA BUANO UTARA KECAMATAN HUAMUAL BELAKANG, KABUPATEN SERAM BAGIAN BARAT

Dusun Anauni salah satu Dusun yang terdapat di pulau Buano dan terletak di sebelah utara dari pulau Buano. Kondisi gastropoda di perairan Anauni mulai memprihatinkan disebabkan banyaknya aktivitas masyarakat yang memanfaatkan perairan sekitar untuk kebutuhan hidup lainnya seperti penangkapan ikan dengan alat tangkap destruktif, membuang sampah ke perairan sekitar, adanya kikisan padang lamun akibat jalur lewat kenderaan lain yang digunakan, dan kegiata bameti. Aktivitas-aktivitas ini berpotensi merusak ekosistem padang lamun dan terumbu karang  yang merupakan habitat dari populasi  gastropoda. Keberadaan Gastropoda di daerah intertidal Dusun Anauni sampai saat ini belum diketahui jenis gastropoda dan distribusi gastropoda. Selin itu masih jarang dilakukan penilitian-penilitian ilmiah di zona intertidal Dusun Anauni Desa Buano Utara Kecamatan Huamual Belakang Kabupaten Seram Bagian Barat. Tujuan dari Penelitian yaitu untuk mengetahui Distribusi Gastropoda di Perairan Dusun Anauni Desa Buano Utara Kecamatan Huamual Belakang. Kegiatan Penelitian ini bertampat di Dusun Anauni Desa Buano Kecamatan Huamual Belakang, Kabupaten Seram Bagian Barat. Dan pelaksanaannya pada bulan Januari 2019. Metode pengambilan data dilakukan pada saat air bergerak surut. metode yang digunakan  dalam pengambilan sampel gastropoda yaitu dengan line transek (Khouw, 2009). Sampel gastropoda yang ditemukan di identifikasi di Laboratorium Bio-Ekologi Program study Ilmu Kelautan dengan menggunakan buku identiikasi (Dharma 1988).  Berdasarkan hasil yang diperoleh pada  penelitian ditemukan 34 spesies yang terdapat di perairan pantai Dusun Anauni tergolong dalam 3 ordo, 12 family dan 17 genus. Spesies yang dominan pada Perairan pantai  Dusun Anauni adalah Morula granulata dan yang sedikit ditemukan yaitu cyprea tirgi

Beberapa Faktor yang Berhubungan dengan Penggunaan Obat Tradisional dalam Pengobatan Sendiri di Indonesia

BEBERAPA FAKTOR YANG BERHUBUNGAN DENGAN PENGGUNAAN OBAT TRADISIONAL DALAM PENGOBATAN SENDIRI DI INDONESI

EFEKTIVITAS MODEL PEMBELAJARAN DISCOVERY LEARNING BERBANTUAN MEDIA POWERPOINT UNTUK MENINGKATKAN HASIL BELAJAR SISWA

This study aims to describe the application of the Discovery Learning learning model assisted by Powerpoint media to students of class X IPA 3 of SMA Negeri 2 Merauke in improving the results of physics learning. This type of research is PTK using a descriptive approach consisting of 2 cycles. Based on the results of this study, it can be concluded that discovery learning learning models make students able to become more active and motivated to find their own solutions to the problems faced. The use of powerpoint media that displays moving images also makes learning more interesting. This is evidenced by an increase in scores at the end of each cycle. To increase the enthusiasm of students, then at the end of the cycle an award is given in the form of congratulations to students or groups that excel.  Keywords: Media Powerpoint, Discovery Learning, Learning OutcomesPenelitian ini bertujuan untuk mendeskripsikan penerapan model pembelajaran Discovery Learning berbantuan media Powerpoint pada siswa kelas X IPA 3 SMA Negeri 2 Merauke dalam meningkatkan hasil belajar fisika. Jenis penelitian ini adalah PTK dengan menggunakan pendekatan deskriptif yang terdiri dari 2 siklus. Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa model pembelajaran discovery learning membuat siswa dapat menjadi lebih aktif dan termotivasi menemukan sendiri solusi dari masalah yang dihadapi. Penggunaan media powerpoint yang menampilkan gambar bergerak juga membuat pembelajaran menjadi semakin menarik. Hal ini terbukti dengan adanya peningkatan skor pada tiap akhir siklus. Untuk menambah semangat peserta didik, maka pada akhir siklus diberikan penghargaan berupa ucapan selamat bagi siswa atau kelompok yang berprestasi. Kata Kunci: Media Powerpoint, Discovery Learning, Hasil Belaja

Enzymology of the branched-chain amino acid oxidation disorders: the valine pathway

Valine is one of the three branched-chain amino acids which undergoes oxidation within mitochondria. In this paper, we describe the current state of knowledge with respect to the enzymology of the valine oxidation pathway and the different disorders affecting oxidation

Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo.

Synapses are an early pathological target in many neurodegenerative diseases ranging from well-known adult onset conditions such as Alzheimer and Parkinson disease to neurodegenerative conditions of childhood such as spinal muscular atrophy (SMA) and neuronal ceroid lipofuscinosis (NCLs). However, the reasons why synapses are particularly vulnerable to such a broad range of neurodegeneration inducing stimuli remains unknown. To identify molecular modulators of synaptic stability and degeneration, we have used the Cln3-/- 33 mouse model of a juvenile form of NCL. We profiled and compared the molecular composition of anatomically-distinct, differentially-affected pre-synaptic populations from the Cln3-/- 35 mouse brain using proteomics followed by bioinformatic analyses. Identified protein candidates were then tested using a Drosophila CLN3 model to study their ability to modify the CLN3-neurodegenerative phenotype in vivo. We identified differential perturbations in a range of molecular cascades correlating with synaptic vulnerability, including valine catabolism and rho signalling pathways. Genetic and pharmacological targeting of key ‘hub’ proteins in such pathways was sufficient to modulate phenotypic presentation in a Drosophila CLN3 model. We propose that such a workflow provides a target rich method for the identification of novel disease regulators which could be applicable to the study of other conditions where appropriate models exist

Efisiensi Penggunaan Larutan Alkali Naoh dalam Pengolahan Rumput Laut Eucheuma Menjadi Semikaraginan

Penelitian “Efsiensi Penggunaan Larutan Alkali Dalam Pengolahan Rumput Laut Euchema Menjadi Semikaraginan“, dilakukan dengan tujuan untuk mengkaji efsiensi penggunaan larutan alkali dalam hal ini NaOH dalam proses pengolahan semikaraginan. Adapun perlakuan yang diberikan dalam penelitian ini adalah A = Jenis rumput laut terdiri dari A1 = Eucheuma cottonii; A2 = Eucheuma spinosum; B = Konsentrasi larutan NaOH terdiri dari B1 = 0,5N dengan tiga tingkatan perendaman, B11 = Perendaman I (0,5N), B12 = Perendaman II (sisa rendaman I setelah penetapan N), B13 = Perendaman III (sisa rendaman II setelah penetapan N); B2 = 1N dengan tiga tingkatan perendaman, B21 = Perendaman I (1N), B22 = Perendaman II (sisa rendaman I setelah penetapan N), B23 = Perendaman III (sisa rendaman II setelah penetapan N). Parameter yang diuji adalah rendaman, kadar air, kadar abu dan kadar karaginan. Hasil penelitian menunjukkan bahwa perlakuan alkali dapat meningkatkan mutu rumput laut, dalam hal ini kadar karaginannya. Konsentrasi alkali (NaOH) terbaik untuk rumput laut jenis Eucheuma cottonii adalah 1N, sedangkan jenis Eucheuma spinosum adalah 0,5N. Disarankan untuk efsiensi penggunaan alkali, maka sisa rendaman I dan II dapat digunakan kembali setelah disaring untuk mendapatkan larutan alkali yang lebih bersih, dan bila perlu dilakukan penambahan konsentrasi alkali untuk menaikan konsentrasi alkali sesuai yang diinginkan

Dynamics Twin Cannibalism of Two Predator and Two Prey System with Prey Defense

The study discusses the condition of the existence of all non-negative equilibrium points. There are 9 realistic equilibrium points from the constructed model. A local stable condition is obtained, a point of equilibrium that is completely biologically feasible. The analytical method on the mathematically formed model is limited, so numerical simulation is also given to explore the model. Numerical simulation is intervened in a model that will show growth in trajectories. The tendency of trajectories in prey one and predator one species is relatively the same because the interactions that occur are intensive. Likewise, prey two and predator two occur, and the interactions that occur cause population growth grow to fluctuate. Differences occur in both types of species, namely predator-prey one and predator-prey two. In the one interaction group, growth tends to be more volatile and moves slowly towards the point of stability in population growth. Incidence is inversely proportional to the interaction of species two which tend to be faster towards the stability point. In general, the results of numerical simulations show that there is a pattern formation in the predator-prey system that grows sustainabley

Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria

3-Hydroxyisobutyric aciduria is a rare entity and affected individuals display a range of clinical manifestations including dysmorphic features and neurodevelopmental problems in the majority of patients. Here, we present two novel patients with 3-hydroxyisobutyric aciduria. To our knowledge, these are the 11th and 12th cases of 3-hydroxyisobutyic aciduria reported. It is believed that a deficiency in 3-hydroxyisobutyrate dehydrogenase is the most likely cause of this disorder. Measurement of 3-hydroxyisobutyrate dehydrogenase activity in fibroblasts homogenates of the two newly identified patients and a previously reported patient, however, revealed similar activities as in control fibroblasts. Since other enzymes with overlapping substrate specificity could conceal abnormal 3-hydroxyisobutyrate dehydrogenase activity, we cloned a candidate human cDNA for 3-hydroxyisobutyrate dehydrogenase (HIBADH). By heterologous expression in Escherichia coli, we showed that the product of the HIBADH gene indeed displays 3-hydroxyisobutyrate dehydrogenase activity. Mutation analysis of the corresponding gene in the patients suffering from 3-hydroxyisobutyric aciduria revealed no mutations. We conclude that HIBADH is not the causative gene in 3-hydroxyisobutyric aciduri