40,797 research outputs found
A Layman's guide to SUSY GUTs
The determination of the most straightforward evidence for the existence of
the Superworld requires a guide for non-experts (especially experimental
physicists) for them to make their own judgement on the value of such
predictions. For this purpose we review the most basic results of Super-Grand
unification in a simple and clear way. We focus the attention on two specific
models and their predictions. These two models represent an example of a direct
comparison between a traditional unified-theory and a string-inspired approach
to the solution of the many open problems of the Standard Model. We emphasize
that viable models must satisfy {\em all} available experimental constraints
and be as simple as theoretically possible. The two well defined supergravity
models, and , can be described in terms of only a few
parameters (five and three respectively) instead of the more than twenty needed
in the MSSM model, \ie, the Minimal Supersymmetric extension of the Standard
Model. A case of special interest is the strict no-scale
supergravity where all predictions depend on only one parameter (plus the
top-quark mass). A general consequence of these analyses is that supersymmetric
particles can be at the verge of discovery, lurking around the corner at
present and near future facilities. This review should help anyone distinguish
between well motivated predictions and predictions based on arbitrary choices
of parameters in undefined models.Comment: 25 pages, Latex, 11 figures (not included), CERN-TH.7077/93,
CTP-TAMU-65/93. A complete ps file (1.31MB) with embedded figures is
available by request from [email protected]
Topological Correlations in a Layer Adsorbed on a Crystal Surface
The incoherent scattering of electrons by a layer adsorbed at a single crystal surface is
determined by the topological correlations of elements forming the adsorbed layer. The model for the
description of atoms or molecules adsorbed on the surface is formulated in terms of occupation
operators which are expressed in terms of pseudospin operators with a given spin value. The
correlations can be determined by the fluctuation dissipation theorem in connection with the
susceptibility or given directly by means of the Green functions properly chosen. An example of the
topological or chemical disorder of two components is considered in detail. The calculations of the
topological correlations allow us to find the incoherent scattering amplitude as a function of the
surface coverage which can be experimentally detected.Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 zostało dofinansowane ze środków MNiSW w ramach działalności upowszechniającej naukę
Dual Response Models for the Fractional Quantum Hall Effect
It is shown that the Jain mapping between states of integer and fractional
quantum Hall systems can be described dynamically as a perturbative
renormalization of an effective Chern-Simons field theory. The effects of
mirror duality symmetries of toroidally compactified string theory on this
system are studied and it is shown that, when the gauge group is compact, the
mirror map has the same effect as the Jain map. The extrinsic ingredients of
the Jain construction appear naturally as topologically non-trivial field
configurations of the compact gauge theory giving a dynamical origin for the
Jain hierarchy of fractional quantum Hall states.Comment: 8 pages LaTe
A new scenario for string unification
We present a new scenario for gauge coupling unification in flipped SU(5)
string models, which identifies the scale of SU(3) and SU(2)
unification with the empirical ~GeV scale, and the
scale of SU(5) and U(1) unification with the theoretical ~GeV string unification scale. The vacuum shift
necessary for the cancellation of the anomalous and an SU(4)
hidden sector with fractionally-charged particles, play a crucial role in the
dynamical determination of all intermediate mass scales in this scenario.Comment: 8 pages, LaTeX, 2 figures (uuencoded
Stacking-induced fluorescence increase reveals allosteric interactions through DNA
From gene expression to nanotechnology, understanding and controlling DNA requires a detailed knowledge of its higher order structure and dynamics. Here we take advantage of the environment-sensitive photoisomerization of cyanine dyes to probe local and global changes in DNA structure. We report that a covalently attached Cy3 dye undergoes strong enhancement of fluorescence intensity and lifetime when stacked in a nick, gap or overhang region in duplex DNA. This is used to probe hybridization dynamics of a DNA hairpin down to the single-molecule level. We also show that varying the position of a single abasic site up to 20 base pairs away modulates the dye–DNA interaction, indicative of through-backbone allosteric interactions. The phenomenon of stacking-induced fluorescence increase (SIFI) should find widespread use in the study of the structure, dynamics and reactivity of nucleic acids
Gene deficiency in activating Fcγ receptors influences the macrophage phenotypic balance and reduces atherosclerosis in mice
Immunity contributes to arterial inflammation during atherosclerosis. Oxidized low-density lipoproteins induce an autoimmune response characterized by specific antibodies and immune complexes in atherosclerotic patients. We hypothesize that specific Fcγ receptors for IgG constant region participate in atherogenesis by regulating the inflammatory state of lesional macrophages. In vivo we examined the role of activating Fcγ receptors in atherosclerosis progression using bone marrow transplantation from mice deficient in γ-chain (the common signaling subunit of activating Fcγ receptors) to hyperlipidemic mice. Hematopoietic deficiency of Fcγ receptors significantly reduced atherosclerotic lesion size, which was associated with decreased number of macrophages and T lymphocytes, and increased T regulatory cell function. Lesions of Fcγ receptor deficient mice exhibited increased plaque stability, as evidenced by higher collagen and smooth muscle cell content and decreased apoptosis. These effects were independent of changes in serum lipids and antibody response to oxidized low-density lipoproteins. Activating Fcγ receptor deficiency reduced pro-inflammatory gene expression, nuclear factor-κB activity, and M1 macrophages at the lesion site, while increasing anti-inflammatory genes and M2 macrophages. The decreased inflammation in the lesions was mirrored by a reduced number of classical inflammatory monocytes in blood. In vitro, lack of activating Fcγ receptors attenuated foam cell formation, oxidative stress and pro-inflammatory gene expression, and increased M2-associated genes in murine macrophages. Our study demonstrates that activating Fcγ receptors influence the macrophage phenotypic balance in the artery wall of atherosclerotic mice and suggests that modulation of Fcγ receptor-mediated inflammatory responses could effectively suppress atherosclerosis
- …