Otitis Media and Internal with Brainstem Extension in a French Bulldog

Background: Otitis is a frequent condition in dogs, with a multifactorial etiology covering primary causes, predisposing and perpetuating factors. It is characterized by an inflammatory process of structures that make up the auditory system, with prevalence data ranging from 15 to 20%, which can occur in any age group and without sex predisposition. According to the location, it can be classified as uni or bilateral, affecting the outer, middle and / or inner ear, the latter two being associated with neurological changes such as vestibulopathy, facial nerve paresis and Horner's syndrome. The morbidity and mortality of otitis media and internal may increase with delay in diagnosis, resulting in delay in the correct treatment, and the extension to brainstem is described in felines and considered rare in dogs. The present study aims to report an atypical case of otitis media and internal, with extension to the brain parenchyma in a brachycephalic dog.Case: A 3-year-old bitch French Bulldog canine was seen, weighing 12 kg, with a history of vomiting, apathy, nystagmus, ataxia and acute evolution hemiparesis. As a result of adoption, it was not known about the animal's morbid past. On special physical and clinical examination, depressed mental status, changes in postural reactions, nostril stenosis with unilateral mucopurulent nasal discharge, corneal ulcer, palpebral and labial ptosis, absence of eyelid reflex and spontaneous strabismus were observed, all of these findings observed on the left side of the face. No signs of otitis external to otoscopy were found. The clinical signs found characterize left facial nerve paresis and peripheral and central vestibulopathy. Otitis media / internal and meningoencephalitis were suspected. Hemogram, serum biochemistry (glucose, urea, creatinine, alanine aminotransferase, total proteins, albumin, globulin, alkaline phosphatase, gamma glutamyltransferase, phosphorus, total bilirubin, cholesterol and total calcium), urinalysis, rapid tests for erlichiosis, anaplasms , borreliosis, heartworm, distemper and leishmaniasis, CSF analysis, neurological panel performed by PCR (Polymerase Chain Reaction) that tested the animal for Bartonellosis, Lyme Disease (Borrelia burgdorferi), Blastomyces dermatitidis, Cryptococcus sp., Virus West Nile, Distemper, Toxoplasmosis, Neosporose and Coccidioides sp. using conjunctival swab, whole blood, urine and CSF samples. The samples were negative for all of these tests. As an image exam, brain magnetic resonance was performed. In the latter, otitis media and left internal was observed with extension of the lesion to the brain parenchyma. CSF analysis showed cytological changes compatible with a non-suppurative inflammatory process, mild pleocytosis with predominantly mononuclear leukocyte infiltrate. As a form of treatment, antibiotic therapy and total ablation of the auditory canal with lateral bulectomy were performed, showing good results with reduced clinical symptoms.Discussion: It is concluded that although the diagnosis of otitis media and internal with extension to brainstem is more common in cats, it should be included as a differential for central vestibular disorders in dogs, and that the diagnosis together with early and effective treatment are important, since that the evolution of the infection to the central nervous system represents a risk to the patient.Keywords: vestibulopathy, meningoencephalitis, brachycephalic.Descritores: vestibulopatia, meningoencefalite, braquicefálico.Título: Otite média e interna com extensão para tronco encefálico em cão buldogue francês

Distribuição espaço-temporal dos desastres climáticos de estiagem e de seca na região do Curimataú paraibano

O presente trabalho tem por objetivo analisar a distribuição espaço-temporal dos reconhecimentos de Situação de Emergência associados à dinâmica climática na região pluviometricamente homogênea do Curimataú Paraibano, durante o período de 2003 a 2016, com enfoque aos decretos de estiagem e seca. Para isso, os dados utilizados foram adquiridos no site do Ministério da Integração Nacional, na página da Secretaria Nacional de Proteção e Defesa Civil, conforme disponibilizados pelas portarias reconhecidas de Situação de Emergência – SE. Como resultado principal, constatou-se um total de 287 reconhecimentos na área de estudo. Destes, 258 correspondem aos desastres de tipo estiagem e 29 do tipo seca. Entende-se que os resultados tiveram um cunho mais descritivo, sendo necessários estudos mais aprofundados sobre o tema

V Congresso Paranaense de Educação Química

O Congresso Paranaense de Educação Química (CPEQUI) é um evento bianual organizado pela comunidade de ensino de Química do estado do Paraná, e realizado em Instituições de Ensino Superior que mantém cursos de Licenciatura em Química. A 5ª edição ocorreu na Universidade Estadual de Maringá, e teve como tema: “Educação Química e políticas educacionais: impactos no ensino, na pesquisa e na formação de professores”. Considerando a importância dos estudantes desenvolverem  a capacidade argumentativa, o pensamento crítico foi tema da Conferência de Abertura “Formação, Inovação e Investigação sobre o Pensamento Crítico na Educação em Ciências” proferida pelo Prof. Dr. Rui Marques Vieira e pela Profª Drª Celina Tenreiro-Vieira da Universidade de Aveiro (Portugal); e tema da Mesa-Redonda “Reflexões acerca do pensamento crítico no contexto educacional”, composta pela Profª Drª Celina Tenreiro-Vieira (Universidade de Aveiro), pela Profª Neide Kiouranis (UEM) e pelo Prof. Dr. Gerson Mol (UnB). No decorrer das atividades realizadas, foram feitas homenagens ao educador, e patrono da educação brasileira, Paulo Freire. Ao rememorar o legado de Freire, professores e pesquisadores buscaram promover junto aos participantes do evento um espaço de reflexão sobre um momento histórico no qual as políticas públicas relacionadas à educação são tão incertas; e de onde surgem propostas de fragmentação da escola. Fica então o questionamento, o que esperar de propostas que vão na contramão da pedagogia libertadora proposta por Paulo Freire? Propostas que negam a liberdade de pensamento na escola. Espaço esse de formação do pensamento crítico

Estimation of the DNA damage in Girardia tigrina (Girard, 1850) after exposure to radiation under extreme conditions / Estimativa dos danos do DNA em Girardia tigrina (Girard, 1850) após exposição à radiação em condições extremas

The use of planarians as experimental models has been increased worldwide especially due to their high capacity of tissue regeneration and ease of laboratory maintenance. The current study aims to assess the genetic damage of Girardia tigrina after exposure of stressors in conditions such as: critical temperature, critical pH, hypergravity (4.4G) and low power laser (685nm). 18 specimens of G. tigrina were used, the extreme conditions mentioned were experimental group with 3 specimens each, and 3 for the control group, all specimens were submitted to the Comet Assay after exposure of stressors, and control group with no extreme condition exposure. The extreme stimuli of critical temperature and pH, hypergravity and low power laser irradiation, caused genetic damages to the G. tigrina, for hypergravity and low-power laser stressors the damage was higher in the pharyngeal and post-pharyngeal regions of the animal with a greatest area of comet tail dragging for the post-pharyngeal region. The extreme stimuli of critical temperature and pH, hypergravity and low power laser irradiation caused genetic damages in planarians Brazilian Journal of Development ISSN: 2525-8761 12160 Brazilian Journal of Development, Curitiba, v.8, n.2, p.12159-12177 feb. 2022. G. tigrina, especially in samples from the pharyngeal and post-pharyngeal regions of the flatworms body assessed by the Comet Assay

O ESTUDO DAQUI É O MEDO DE LÁ: IMPLEMENTAÇÃO DA LEI 10.639/03 NOS LIVROS DIDÁTICOS

O objetivo do artigo será o de apresentar as condições históricas, sociais e políticas que possibilitaram mudanças e permanências na representação da história e cultura africana e afro-brasileira nos livros didáticos após a declaração da lei 10.639/03. Considerando que o livro didático é um importante elemento no contexto escolar para o ensino de História e das demais áreas do conhecimento e decorridos 15 (quinze) anos da declaração da lei 10.639/03, buscamos verificar se houve transformações significativas nos livros didáticos referente a abordagem a história e cultura de povos africanos e afro-brasileiros. Buscamos analisar se visões reducionistas sobre os povos negros e africanos ou a ausência dessas populações nos livros didáticos foram superadas, de forma a ajudar desconstruir o processo de racialização, antes não discutido como preocupação importante na formulação de políticas educacionais nacionais

Food consumption and cardiovascular risk in disease-free women with polycystic ovary syndrome:: a cross-sectional study in Northeast Brazil

Objective: To investigate the association between dietary intake, nutritional status and cardiovascular risk markers in women with polycystic ovary syndrome (PCOS) without other chronic diseases.Methods: This cross-sectional study included 59 women diagnosed with PCOS and 126 age-matched healthy controls. Data collected consisted of socio-demographic and behavioral variables, weight, height, body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHTR), lipid accumulation products (LAP), serum triglycerides (TG) level, body fat percentage (BFP), and food consumption. Quantitative and qualitative food intake were verified by applying a food frequency questionnaire.Results: BMI, WC, WHTR and LAP index values as well as TG levels, but not BFP values, were significantly increased in the PCOS group as compared to controls (p<0.05). In the control group, eutrophic women had slightly higher TG levels, whereas obese women were younger in the PCOS group (p<0.05). In both groups, the consumption of carbohydrates and proteins was adequate, but fiber intake was insufficient. In the PCOS group, energy consumption was excessive, while carbohydrate intake was higher than in controls, but adequate.Conclusion: Although diseasefree PCOS women showed enhanced inadequacy in dietary intake and nutritional status and increased cardiovascular impairment, no correlation between dietary intake, nutritional status and cardiovascular risk markers was found.Key words: Polycystic ovary syndrome; Eating; Cardiovascular diseases; Nutritional status

Aplicabilidade dos Métodos de Predição COST231 e Miura na Cobertura Outdoor-Indoor na faixa de 700 MHz / Applicability of COST231 and Miura Prediction Methods in Outdoor-Indoor Coverage in the 700 MHz Band

This work consists in verifying two prediction models applied in outdoor-to-indoor coverage, but now taking in consideration that there is some vegetation between the transmission antenna and the indoor environment and lateral obstacles. Measurements on a 768 MHz carrier were carried out along the corridors, in four floors, inside a building and the models were adjusted to the local mean of the received signal, leading to the conclusion that the multipath has great influence in the received signal levels, presenting a considerable difference in relation to the proposed models.