Anomaly in the K^0_S Sigma^+ photoproduction cross section off the proton at the K* threshold

The $\gamma + p \rightarrow K^0 + \Sigma^+$ photoproduction reaction is investigated in the energy region from threshold to $E_\gamma = 2250$\,MeV. The differential cross section exhibits increasing forward-peaking with energy, but only up to the $K^*$ threshold. Beyond, it suddenly returns to a flat distribution with the forward cross section dropping by a factor of four. In the total cross section a pronounced structure is observed between the $K^*\Lambda$ and $K^*\Sigma$ thresholds. It is speculated whether this signals the turnover of the reaction mechanism from t-channel exchange below the $K^*$ production threshold to an s-channel mechanism associated with the formation of a dynamically generated $K^*$-hyperon intermediate state.Comment: 14 pages, 7 figure

Linearly polarised photon beams at ELSA and measurement of the beam asymmetry in pi^0-photoproduction off the proton

At the electron accelerator ELSA a linearly polarised tagged photon beam is produced by coherent bremsstrahlung off a diamond crystal. Orientation and energy range of the linear polarisation can be deliberately chosen by accurate positioning of the crystal with a goniometer. The degree of polarisation is determined by the form of the scattered electron spectrum. Good agreement between experiment and expectations on basis of the experimental conditions is obtained. Polarisation degrees of P = 40% are typically achieved at half of the primary electron energy. The determination of P is confirmed by measuring the beam asymmetry, \Sigma, in pi^0 photoproduction and a comparison of the results to independent measurements using laser backscattering.Comment: 9 pages, 10 figures, submitted to EPJ

Association of Polymorphisms in <i>PPARPGC1A,ACE</i>, and <i>DRD2 G</i>enes with Gestational Diabetes Mellitus

The aim of our research was to study the distribution of polymorphic variants of the DRD2/ANKK1 TaqIA (rs1800497 SNP), PPARGC1A rs8192678 SNP, and ACE I/D in gestational diabetes mellitus (GDM). Methods and Results: The study included 383 pregnant women (gestational age of 37.0-41.0 weeks) with GDM and 68 pregnant women without disturbed carbohydrate metabolism. This was a prospective case-control study. All patients were divided into 3 groups. Group 1 included 211 pregnant women with GDM who received diet therapy only; Group 2 included 172 pregnant women with GDM who received insulin therapy; Group 3 included 68 pregnant women without metabolic disorders. For the DRD2/ANKK1 TaqIA (rs1800497 SNP) (A1/A2; T/C), we found that the TT homozygous genotype and T allele prevailed in Groups with GDM compared with Group without metabolic disorders. Conclusion : A study of the DRD2/ANKK1 TaqIA (rs1800497 SNP), PPARGC1A rs8192678 SNP, and ACE I/D revealed statistically significant increased risks for GDM in carriers of the TT genotype and T allele of the DRD2/ANKK1 TaqIA (rs1800497 SNP)

Predictive markers of missed miscarriage

The aim of this study was to find useful the serological markers for missed miscarriage (MM) in order to predict the outcome of pregnancy. The study included 141 pregnant women aged between 18 and 45 years at gestational age under 11 weeks. All women were divided into 3 groups. Group 1 included 68 women with MM; Group 2 included 43 women with spontaneous miscarriage; Group 3 included 30 pregnant women without pathology. Proteomic analysis of the blood serum was performed using liquid chromatography-mass spectrometry. The results of our study show that immunoglobulin kappa variable 3-15 (KV315) can be considered as the most promising serologic marker for MM in early gestation. The potential role of KV315 as the serological marker is very important for predicting the course of pregnancy.(International Journal of Biomedicine. 2021;11(1):65-67.). © 2021, International Medical Research and Development Corporation. All rights reserved

The results of bacteriological examination in premature infants with neonatal morbidity and mortality

The purpose of this study was to assess the results of bacteriological studies in children born prematurely and compare the received data with the detected neonatal morbidity. Methods and Results: Our study included 227 pregnant women at gestational age of 28-36 weeks 6 days, and their newborns. Depending on the gestational age, they were divided into 3 groups. Group 1 included 73 women at gestational age of 28-30 weeks 6 days; Group 2 included 81 women at gestational age of 31-33 weeks 6 days, Group 3 included 73 women at gestational age of 34-36 weeks 6 days. All women underwent an assessment of vaginal microcenosis and the quantitative and qualitative composition of the biotope of the cervical discharge; the newborns underwent bacteriological examination of the auricle, pharynx and anus. Analysis of the results of bacteriological studies shows a significant growth of microorganisms in newborns from mothers of Group 1. The analysis of morbidity among premature infants showed that in each group there were 2 or 3 diseases, mainly of an infectious nature. The main proportion of morbidity (congenital pneumonia and infections of the perinatal period, diseases of the urinary system, neonatal jaundice of premature infants and cerebral ischemia) among newborns was found in Group 1, compared with Groups 2 and 3. The analysis of the results obtained showed that the low birth weight in preterm labor correlated with the growth of Staphylococcus epidermidis in the throat of newborns. Neonatal jaundice of premature newborns was characterized by 100% detection of Staphylococcus epidermidis and Serratia odorifera in the anus swabs, and Staphylococcus epidermidis in swabs from the pharynx and ear. Congenital pneumonia positively correlated with the growth of Staphylococcus epidermidis, E. coli, Candida spp, Enterococcus faecalis in the throat swab. The deceased children had a co-infection. Conclusion: Our study identified the main microorganisms affecting both perinatal morbidity and neonatal mortality: Staphylococcus epidermidis, Enterococcus faecalis, E. coli, Candida spp. It is necessary to note the frequent identification of E. coli strains resistant to the main antibacterial drugs. © 2020, International Medical Research and Development Corporation. All rights reserved