437 research outputs found

    Nanotechnological approaches to enhance anticancer chemo-immunotherapy

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    Thermal simulations for optical transition radiation screen for Eli-NP compton gamma source

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    The ELI-NP GBS (Extreme Light Infrastructure-Nuclear Physics Gamma Beam Source) is a high brightness elec-tron LINAC that is being built in Romania. The goal for this facility is to provide high luminosity gamma beam through Compton Backscattering. A train of 32 bunches at 100Hz with a nominal charge of 250pC is accelerated up to 740 MeV. Two interaction points with an IR Laser beam produces the gamma beam at different energies. In order to measure the electron beam spot size and the beam proper-ties along the train, the OTR screens must sustain the ther-mal and mechanical stress due to the energy deposited by the bunches. This paper is an ANSYS study of the issues due to the high quantity of energy transferred to the OTR screen. They will be shown different analysis, steady-state and thermal transient analysis, where the input loads will be the internal heat generation equivalent to the average power, deposited by the ELI-GBS beam in 512 ns, that is the train duration. Each analyses will be followed by the structural analysis to investigate the performance of the OTR materi

    Thermal issues for the optical transition radiation screen for the ELI-NP compton gamma source

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    A high brightness electron LINAC is being built in the Compton Gamma Source at the ELI Nuclear Physics facility in Romania. To achieve the design luminosity, a train of 32 bunches, 16 ns spaced, with a nominal charge of 250 pC will collide with a laser beam in two interaction points. Electron beam spot size is measured with Optical Transition Radiation (OTR) profile monitors. In order to measure the beam properties, the OTR screens must sustain the thermal and mechanical stress due to the energy deposited by bunches. This paper is an ANSYS study of the issues due to the high energy transferred to the OTR screens. Thermal multicycle analysis will be shown; each analysis will be followed by a structural analysis in order to investigate the performance of the materia

    Conceptual design of electron beam diagnostics for high brightness plasma accelerator

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    A design study of the diagnostics of a high brightness linac, based on X-band structures, and a plasma accelerator stage, has been delivered in the framework of the EuPRAXIA@SPARC_LAB project. In this paper, we present a conceptual design of the proposed diagnostics, using state of the art systems and new and under development devices. Single shot measurements are preferable for plasma accelerated beams, including emittance, while μ\mum level and fs scale beam size and bunch length respectively are requested. The needed to separate the driver pulse (both laser or beam) from the witness accelerated bunch imposes additional constrains for the diagnostics. We plan to use betatron radiation for the emittance measurement just at the end of the plasma booster, while other single-shot methods must be proven before to be implemented. Longitudinal measurements, being in any case not trivial for the fs level bunch length, seem to have already a wider range of possibilities

    What should a quantitative model of masking look like and why would we want it?

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    Quantitative models of backward masking appeared almost as soon as computing technology was available to simulate them; and continued interest in masking has lead to the development of new models. Despite this long history, the impact of the models on the field has been limited because they have fundamental shortcomings. This paper discusses these shortcomings and outlines what future quantitative models should look like. It also discusses several issues about modeling and how a model could be used by researchers to better explore masking and other aspects of cognition

    Longitudinal phase-space manipulation with beam-driven plasma wakefields

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    The development of compact accelerator facilities providing high-brightness beams is one of the most challenging tasks in field of next-generation compact and cost affordable particle accelerators, to be used in many fields for industrial, medical and research applications. The ability to shape the beam longitudinal phase-space, in particular, plays a key role to achieve high-peak brightness. Here we present a new approach that allows to tune the longitudinal phase-space of a high-brightness beam by means of a plasma wakefields. The electron beam passing through the plasma drives large wakefields that are used to manipulate the time-energy correlation of particles along the beam itself. We experimentally demonstrate that such solution is highly tunable by simply adjusting the density of the plasma and can be used to imprint or remove any correlation onto the beam. This is a fundamental requirement when dealing with largely time-energy correlated beams coming from future plasma accelerators
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