Exploring the Perceived Relationship Between Parent-Child Socialization and Adult Children\u27s Romantic Experiences

Romantic relationship experiences are related to experiences in the family of origin such as parenting, parents’ romantic history, and patterns of interaction within families. However, there is a lack of research about how adult children perceive their socialization about romantic relationships. This study used qualitative data from relationship history interviews (N= 35) to explore how adults discuss their parents’ influence on their romantic relationship development. The findings suggest that the level of support, love, and affirmation they perceived from their parents in childhood was reflected in their adulthood intimate relationships. Moreover, participants viewed their parents as either good or bad role models, and they adjusted their partner choices and their behavior in relationships based on whether they wanted to be like their parents or avoid being like their parents. The findings suggest that parents’ influence on romantic socialization is still relevant in adulthood

Multicolored parallelisms of Hamiltonian cycles

AbstractA subgraph in an edge-colored graph is multicolored if all its edges receive distinct colors. In this paper, we prove that a complete graph on 2m+1 vertices K2m+1 can be properly edge-colored with 2m+1 colors in such a way that the edges of K2m+1 can be partitioned into m multicolored Hamiltonian cycles

Interaction of Proliferation Cell Nuclear Antigen (PCNA) with c-Abl in Cell Proliferation and Response to DNA Damages in Breast Cancer

Cell proliferation in primary and metastatic tumors is a fundamental characteristic of advanced breast cancer. Further understanding of the mechanism underlying enhanced cell growth will be important in identifying novel prognostic markers and therapeutic targets. Here we demonstrated that tyrosine phosphorylation of the proliferating cell nuclear antigen (PCNA) is a critical event in growth regulation of breast cancer cells. We found that phosphorylation of PCNA at tyrosine 211 (Y211) enhanced its association with the non-receptor tyrosine kinase c-Abl. We further demonstrated that c-Abl facilitates chromatin association of PCNA and is required for nuclear foci formation of PCNA in cells stressed by DNA damage as well as in unperturbed cells. Targeting Y211 phosphorylation of PCNA with a cell-permeable peptide inhibited the phosphorylation and reduced the PCNA-Abl interaction. These results show that PCNA signal transduction has an important impact on the growth regulation of breast cancer cells