An overview on the natural enemies of Rhynchophorus palm weevils, with focus on R. ferrugineus.

Rhynchophorus palm weevils are large insects belonging to the family Dryophthoridae. All Rhynchophorus species are polyphagous and have a similar life history but some are major pests because of the serious economic damage they cause, in particular to several species of the family Arecaceae. Here we review the natural enemies of Rhynchophorus species in both their native and introduced regions of the world, to assess the possibility of biological control of this taxon. Moreover, particular attention is paid to the well-studied and harmful species Rhynchophorus ferrugineus, about which more information is available, and to its natural enemies in the Mediterranean region, because the impact of this pest in this recently colonized area is particularly remarkable and also the recent trend in species management is looking for indigenous natural enemies. More than 50 natural enemies have been reported to attack Rhynchophorus species, even if most of them are associated to R. ferrugineus (Olivier), highlighting the lack of information on the other species of the genus. Pros and cons of all the biological control agents are then discussed: among the considered organisms, fungi are noteworthy to be considered for inclusion in integrated pest management programs. Overall, our overview underlines the need to increase knowledge on natural enemies of all the species of the genus Rhynchophorus, to isolate more virulent strains and to determine the optimum conditions for the actions of the biocontrol agents

Large-Mass Ultra-Low Noise Germanium Detectors: Performance and Applications in Neutrino and Astroparticle Physics

A new type of radiation detector, a p-type modified electrode germanium diode, is presented. The prototype displays, for the first time, a combination of features (mass, energy threshold and background expectation) required for a measurement of coherent neutrino-nucleus scattering in a nuclear reactor experiment. The device hybridizes the mass and energy resolution of a conventional HPGe coaxial gamma spectrometer with the low electronic noise and threshold of a small x-ray semiconductor detector, also displaying an intrinsic ability to distinguish multiple from single-site particle interactions. The present performance of the prototype and possible further improvements are discussed, as well as other applications for this new type of device in neutrino and astroparticle physics (double-beta decay, neutrino magnetic moment and WIMP searches).Comment: submitted to Phys. Rev.

Surto policlonal de infecção de corrente sanguínea causada pelo complexo Burkholderia cepacia em unidades de hospital-dia de hematologia e transplante de medula óssea

Aim: The objective was to describe an outbreak of bloodstream infections by Burkholderia cepacia complex (Bcc) in bone marrow transplant and hematology outpatients. Methods: On February 15, 2008 a Bcc outbreak was suspected. 24 cases were identified. Demographic and clinical data were evaluated. Environment and healthcare workers' (HCW) hands were cultured. Species were determined and typed. Reinforcement of hand hygiene, central venous catheter (CVC) care, infusion therapy, and maintenance of laminar flow cabinet were undertaken. 16 different HCWs had cared for the CVCs. Multi-dose heparin and saline were prepared on counter common to both units. Findings: 14 patients had B. multivorans (one patient had also B. cenopacia), six non-multivorans Bcc and one did not belong to Bcc. Clone A B. multivorans occurred in 12 patients (from Hematology); in 10 their CVC had been used on February 11/12. Environmental and HCW cultures were negative. All patients were treated with meropenem, and ceftazidime lock-therapy. Eight patients (30%) were hospitalized. No deaths occurred. After control measures (multidose vial for single patient; CVC lock with ceftazidime; cleaning of laminar flow cabinet; hand hygiene improvement; use of cabinet to store prepared medication), no new cases occurred. Conclusions: This polyclonal outbreak may be explained by a common source containing multiple species of Bcc, maybe the laminar flow cabinet common to both units. There may have been contamination by B. multivorans (clone A) of multi-dose vials.O objetivo foi descrever um surto de infecções da corrente sanguínea por complexo B. cepacia (Bcc) nos ambulatórios de hematologia e transplante de medula óssea. Métodos: Em 15/02/2008, um surto de Bcc foi suspeitado. 24 casos foram identificados. Os dados demográficos e clínicos foram avaliados. Mãos de profissionais da saúde e ambiente foram cultivadas. Espécies foram determinadas e tipadas. Reforço da higiene das mãos, cuidados com cateteres, terapia de infusão e manutenção da câmara de fluxo laminar foram realizadas. 16 profissionais de saúde (PS) diferentes manipularam os cateteres. Heparina multidoses e soro eram preparadas em um balcão comum a ambas as unidades. Resultados: 14 pacientes tiveram B. multivorans (um paciente teve também B. cenopacia), 6 Bcc não-multivorans e um teve um agente não pertencente a Bcc. Clone A de B. multivorans ocorreu em 12 pacientes (da Hematologia), em 10 o cateter havia sido utilizado nos dias 11 ou 12 de fevereiro. Culturas ambientais e de PS foram negativos. Todos os pacientes foram tratados com meropenem e selo de ceftazidima. Oito pacientes (30%) foram hospitalizados. Não ocorreram mortes. Após as medidas de controle, nenhum novo caso ocorreu. Conclusões: Este surto policlonal pode ser explicado por uma fonte comum contendo várias espécies de Bcc, talvez a câmara de fluxo laminar comum a ambas as unidades. Pode ter havido contaminação por B. multivorans (clone A) de frascos multi-dose

Use of MODIS images to monitor the sediment inflow into the Três Marias reservoir

Objetivou-se, neste trabalho, monitorar o fluxo de entrada de sedimentos no braço do Rio Indaiá no reservatório de Três Marias, MG, com base em dados das imagens de satélites. Foram adquiridas séries temporais de 12 anos das imagens MODIS (Terra e Aqua), compostas de 8 dias. Estimativas de reflectância da superfície foram calculadas usando-se o algoritmo MOD3R. Dados hidrossedimentométricos da estação de monitoramento do Rio Indaiá foram integrados às análises para se entender a relação entre as respostas das imagens de satélites e as medições de campo. Os resultados apontaram uma forte relação entre os dados de reflectância e a descarga sólida calculada no Rio Indaiá; há, também, uma forte variação da reflectância ao longo do braço do reservatório no sentido da montante à jusante, com altos valores de reflectância à montante e valores baixos à jusante. O percentual de registros válidos estimados nas imagens MODIS atendeu aos requisitos de monitoramento do fluxo de sedimentos enquanto as estimativas de reflectância da água mostraram grande potencial em relacionar as respostas espectrais das imagens de satélites com a variação da descarga sólida de sedimento no braço do Rio Indaiá.This study presents the monitoring of the sediment discharge from the Indaiá River into the Três Marias reservoir, based on the use of satellite images. A 12-year time series of MODIS 8-day image composites (Terra and Aqua on-board sensors) was used in this study. Estimates of the water surface reflectance were calculated using the algorithm MOD3R. River suspended sediment discharge records made available from the CEMIG hydroelectric company were integrated in the analysis to understand the variability of the remote sensing reflectance. The results showed a strong relationship between the reflectance data and the Indaiá river solid discharge. A strong variation of the reflectance is assessed within the reservoir (upstream towards downstream), with high reflectance values upstream (near the river mouth) and low reflectance values downstream. The estimated percentage of valid records in MODIS images met the requirements for monitoring the flow of sediment. Estimates of water reflectance show great potential in relating the sedimentation processes within the Reservoir as a function of time

Design and baseline characteristics of SALT-HF trial: hypertonic saline therapy in ambulatory heart failure

Aims: Hypertonic saline solution (HSS) plus intravenous (IV) loop diuretic appears to enhance the diuretic response in patients hospitalized for heart failure (HF). The efficacy and safety of this therapy in the ambulatory setting have not been evaluated. We aimed to describe the design and baseline characteristics of the SALT-HF trial participants. Methods and results: ‘Efficacy of Saline Hypertonic Therapy in Ambulatory Patients with HF’ (SALT-HF) trial was a multicenter, double-blinded, and randomized study involving ambulatory patients who experienced worsening heart failure (WHF) without criteria for hospitalization. Enrolled patients had to present at least two signs of volume overload, use ≥ 80 mg of oral furosemide daily, and have elevated natriuretic peptides. Patients were randomized 1:1 to treatment with a 1-h infusion of IV furosemide plus HSS (2.6–3.4% NaCl depending on plasmatic sodium levels) versus a 1-h infusion of IV furosemide at the same dose (125–250 mg, depending on basal loop diuretic dose). Clinical, laboratory, and imaging parameters were collected at baseline and after 7 days, and a telephone visit was planned after 30 days. The primary endpoint was 3-h diuresis after treatment started. Secondary endpoints included (a) 7-day changes in congestion data, (b) 7-day changes in kidney function and electrolytes, (c) 30-day clinical events (need of IV diuretic, HF hospitalization, cardiovascular mortality, all-cause mortality or HF-hospitalization). Results: A total of 167 participants [median age, 81 years; interquartile range (IQR), 73–87, 30.5% females] were randomized across 13 sites between December 2020 and March 2023. Half of the participants (n = 82) had an ejection fraction >50%. Most patients showed a high burden of comorbidities, with a median Charlson index of 3 (IQR: 2–4). Common co-morbidities included diabetes mellitus (41%, n = 69), atrial fibrillation (80%, n = 134), and chronic kidney disease (64%, n = 107). Patients exhibited a poor functional NYHA class (69% presenting NYHA III) and several signs of congestion. The mean composite congestion score was 4.3 (standard deviation: 1.7). Ninety per cent of the patients (n = 151) presented oedema and jugular engorgement, and 71% (n = 118) showed lung B lines assessed by ultrasound. Median inferior vena cava diameter was 23 mm, (IQR: 21–25), and plasmatic levels of N-terminal-pro-B-type natriuretic peptide (NTproBNP) and antigen carbohydrate 125 (CA125) were increased (median NT-proBNP 4969 pg/mL, IQR: 2508–9328; median CA125 46 U/L, IQR: 20–114). Conclusions: SALT-HF trial randomized 167 ambulatory patients with WHF and will determine whether an infusion of hypertonic saline therapy plus furosemide increases diuresis and improves decongestion compared to equivalent furosemide administration alone

Gender differences in health and health care utilisation in various ethnic groups in the Netherlands: a cross-sectional study

<p>Abstract</p> <p>Background</p> <p>To determine gender differences in health and health care utilisation within and between various ethnic groups in the Netherlands.</p> <p>Methods</p> <p>Data from the second Dutch National Survey of General Practice (2000–2002) were used. A total of 7,789 persons from the indigenous population and 1,512 persons from the four largest migrant groups in the Netherlands – Morocco, Netherlands Antilles, Turkey and Surinam – aged 18 years and older were interviewed. Self-reported health outcomes studied were general health status and the presence of acute (past 14 days) and chronic conditions (past 12 months). And self-reported utilisation of the following health care services was analysed: having contacted a general practitioner (past 2 months), a medical specialist, physiotherapist or ambulatory mental health service (past 12 months), hospitalisation (past 12 months) and use of medication (past 14 days). Gender differences in these outcomes were examined within and between the ethnic groups, using logistic regression analyses.</p> <p>Results</p> <p>In general, women showed poorer health than men; the largest differences were found for the Turkish respondents, followed by Moroccans, and Surinamese. Furthermore, women from Morocco and the Netherlands Antilles more often contacted a general practitioner than men from these countries. Women from Turkey were more hospitalised than Turkish men. Women from Morocco more often contacted ambulatory mental health care than men from this country, and women with an indigenous background more often used over the counter medication than men with an indigenous background.</p> <p>Conclusion</p> <p>In general the self-reported health of women is worse compared to that of men, although the size of the gender differences may vary according to the particular health outcome and among the ethnic groups. This information might be helpful to develop policy to improve the health status of specific groups according to gender and ethnicity. In addition, in some ethnic groups, and for some types of health care services, the use by women is higher compared to that by men. More research is needed to explain these differences.</p

Interação social entre agentes em ambientes de recursos limitados

Trabalho final de Mestrado para obtenção do grau de Mestre em Engenharia de Redes de Comunicação e MultimédiaO estudo da interação social entre agentes inteligentes é cada vez mais um tema central da investigação em inteligência artificial. Atualmente inseridos numa realidade onde veículos navegam autonomamente, não é difícil imaginar cenários onde estas máquinas poderão trabalhar em conjunto, maximizando as suas capacidades e tornando-se mais eficientes na utilização de recursos e na concretização dos respetivos objetivos. Devido à elevada complexidade computacional dos seus processos internos, ainda é difícil, sobretudo para máquinas com locomoção autónoma no mundo, desenvolver raciocínio social de forma complexa, pelo que este trabalho pretende contribuir com uma abordagem que aproxime a investigação de uma solução viável para cenários reais onde um sistema multi-agente, limitado pelos seus recursos, tem de produzir soluções em tempo real. Este trabalho integra-se na área dos agentes inteligentes, sendo desenvolvido o tema da interação social em arquiteturas de agentes com limitação de recursos. É apresentado um estudo sobre as arquiteturas de agentes reativas e deliberativas e as respetivas potencialidades na constituição de sistemas multi-agente num contexto de limitação de recursos. É feito o estudo do problema da delegação de tarefas numa abordagem de limitação de recursos, onde se propõe um modelo de coordenação com base em mecanismos emocionais para a sua solução.Abstract: The study of social interaction between intelligent agents is increasingly becoming a central topic of research in artificial intelligence. Living in a reality where vehicles navigate autonomously, it is not hard to imagine scenarios in which these machines could work together, maximizing their skills, making better use of their resources and being more eficient on the achievement of objectives. Due to the high computational complexity of the internal processes, it is still dificult, especially for machines with autonomous locomotion, to develop complex social reasoning, so this work aims to contribute to an approach that approximates the research to a viable solution for real scenarios where a multi-agent system, limited by its resources, has to produce solutions in real-time. This work is part of the area of intelligent agents, developing the theme of social interaction on agent architectures working with bounded-resources. It is presented a study about the reactive and deliberative architectures and their potential in the formation of multi-agent systems in a boundedresources context. It is also made a study about the task delegation problema from the resource-bounded point of view, proposing a coordenation model, based on emotional mechanisms