Vitamin B12-catalyzed synthesis of some peracetylated alkyl b-D-xylopyranosides

The vitamin B12-catalyzed glycosylation reaction of brominated b-D-xylose peracetate with alkanols ROH (C1-C8) has been studied. The catalytically active species in this reaction was cob(I)alamin, obtained by chemical reduction of Vitamin B12 with NaBH4 (Co(III) to Co(I)). The reaction was carried out with 2 mol% of vitamin B12, with respect to xylosyl bromide 1, under argon at room temperature. Under these conditions, peracetylated C1-C8-alkyl b-D-xylopyranosides (3a3f) were obtained in moderate yield (5570 %). In all cases 3,4-di-O-acetyl-D-xylal (4) was obtained, as the product of reductive elimination of peracetylated xylosyl bromide (1525 %)

To the environmental responsibility among students through developing their environmental values

This research explores interconnection between environmental values and environmental responsibility among young people. Basic question of this study was whether and to which degree the environmental values influence the development of the environmental responsibility? By answering on this question, we want to provide guidelines for educational activities in schools which aim to develop environmental awareness among the young people of Serbia. The survey covered a sample of 252 students from primary and secondary government schools from Belgrade. Students were tested on a five point Likert type scales which examined environmental responsibility and environmental values. To assess the reliability and validity of the scales standard statistical procedures were used. The results of our study confirmed positive linear dependence between environmental values and environmental responsibility. On the basis of students' environmental values 48% of their environmental responsibility can be predicted On the basis of our results, it is possible to conclude that students who believe that efficient functioning of society and the survival of life on the Earth is unimaginable without environmental protection, display desirable attitudes towards environmental responsibility. The obtained results may help to identify future directions of formal education activities regarding the improvement of personal environmental responsibility among young people

Physicochemically modified peat by thermal and oxidation processes as an active material for purification of wastewaters from certain hazardous pollutants

The physicochemical modification of peat through thermal and oxidation processes was carried out, in order to obtain new, inexpensive and active material for purification of different types of waters. During the modification, surface chemical compounds of Shilov type were formed. Batch adsorption properties and suitability of physicochemically modified peat (PCMP) for odor removal were tested in aqueous solutions of H2S and colloidal sulphur. Additionally, PCMP was tested in the removal of As(V) which is hazardous ingredient in contaminated waters. Possible mechanisms of pollutants binding include interactions, which lead to formation of adducts and clathrates. All these processes are elucidated in detail. The results showed that the obtained material can be used for the removal of sulphide, colloidal sulphur and As(V) from different types of waters

Modeling the effect of the inclination angle on natural convection from a flat plate: the case of a photovoltaic module

status: publishe

Safe pharmacotherapy management of breastfeeding woman in community pharmacy- new pharmaceutical care service

80th FIP World Congress of Pharmacy and Pharmaceutical Sciences Seville, Spain, 18 to 22 September 2022 https://www.fip.org/abstracts?page=abstracts&action=item&item=2362

Predicting severity and intrahospital mortality in CovID-19: The place and role of oxidative stress

SARS-CoV-2 virus causes infection which led to a global pandemic in 2020 with the development of severe acute respiratory syndrome. Therefore, this study was aimed at examining its possible role in predicting severity and intrahospital mortality of COVID-19, alongside with other laboratory and biochemical procedures, clinical signs, symptoms, and comorbidity. This study, approved by the Ethical Committee of Clinical Center Kragujevac, was designed as an observational prospective cross-sectional clinical study which was conducted on 127 patients with diagnosed respiratory COVID-19 viral infection from April to August 2020. The primary goals were to determine the predictors of COVID-19 severity and to determine the predictors of the negative outcome of COVID-19 infection. All patients were divided into three categories: patients with a mild form, moderate form, and severe form of COVID-19 infection. All biochemical and laboratory procedures were done on the first day of the hospital admission. Respiratory (p < 0:001) and heart (p = 0:002) rates at admission were significantly higher in patients with a severe form of COVID-19. From all observed hematological and inflammatory markers, only white blood cell count (9:43 ± 4:62, p = 0:001) and LDH (643:13 ± 313:3, p = 0:002) were significantly higher in the severe COVID-19 group. We have observed that in the severe form of SARS-CoV-2, the levels of superoxide anion radicals were substantially higher than those in two other groups (11:3 ± 5:66, p < 0:001) and the nitric oxide level was significantly lower in patients with the severe disease (2:66 ± 0:45, p < 0:001). Using a linear regression model, TA, anosmia, ageusia, O2-, and the duration at the ICU are estimated as predictors of severity of SARS-CoV-2 disease. The presence of dyspnea and a higher heart rate were confirmed as predictors of a negative, fatal outcome. Results from our study show that presence of hypertension, anosmia, and ageusia, as well as the duration of ICU stay, and serum levels of O2- are predictors of COVID-19 severity, while the presence of dyspnea and an increased heart rate on admission were predictors of COVID-19 mortality