6,674 research outputs found
Associations between dietary added sugar intake and micronutrient intake: a systematic review
Original article can be found at: http://journals.cambridge.org/ Copyright The Authors. DOI: 10.1017/S0007114507617206There is increasing concern that high intakes of added sugars might compromise intakes of micronutrients. The objectives of this systematic review were (1) to determine whether dietary added sugar intake was associated with micronutrient intakes, and if so, whether there was evidence of micronutrient dilution as a result of higher dietary added sugar intake and (2) if micronutrient dilution was present, to determine whether there was sufficiently robust evidence to support a threshold effect above which there was a significant decline in micronutrient intake or status relative to the recommended intakes. A systematic computerised literature search was undertaken, limited to studies written in English published from 1980 onwards and further studies identified through hand searching papers. Fifteen studies that assessed associations between intakes of added sugars or non-milk extrinsic sugars and micronutrients were included. Overall, there are insufficient data and inconsistency between studies in relationships between added sugars and micronutrient intakes, with no clear evidence of micronutrient dilution or a threshold for a quantitative amount of added sugar intake for any of the micronutrients investigated. The current evidence base is considerably constrained by methodological issues. Further research is required to determine which food products high in added sugars might adversely affect micronutrient intakes by displacing other food items from the diet. Analyses should take into account the magnitude of any observed associations to determine their true biological significance.Peer reviewe
An investigation to examine the most appropriate methodology to capture historical and modern preserved anatomical specimens for use in the digital age to improve access: a pilot study
Anatomico-pathological specimens constitute a valuable component of many medical museums or
institutional collections but can be limited in their impact on account of both physical and intellectual
inaccessibility. Further concerns relate to conservation as anatomical specimens may be subject to
tissue deterioration, constraints imposed by spatial or financial limitations of the host institution, or
accident-based destruction. In awareness of these issues, a simple and easily implementable
methodology to increase accessibility, impact and conservation of anatomical specimens is proposed
which combines photogrammetry, object virtual reality (object VR), and interactive portable document
format (PDF) with supplementary historical and anatomical commentary. The methodology was
developed using wet, dry, and plastinated specimens from the historical and modern collections in the
Museum of Anatomy at the University of Glasgow. It was found that photogrammetry yielded excellent
results for plastinated specimens and showed potential for dry specimens, while object VR produced
excellent photorealistic virtual specimens for all materials visualised. Use of PDF as output format was
found to allow for the addition of textual, visual, and interactive content, and as such supplemented the
virtual specimen with multidisciplinary information adaptable to the needs of various audiences. The
results of this small-scale pilot study indicate the beneficial nature of combining these established
techniques into a methodology for the digitisation and utilisation of historical anatomical collections in
particular, but also collections of material culture more broadly
Post-outburst X-ray flux and timing evolution of Swift J1822.3-1606
Swift J1822.3-1606 was discovered on 2011 July 14 by the Swift Burst Alert
Telescope following the detection of several bursts. The source was found to
have a period of 8.4377 s and was identified as a magnetar. Here we present a
phase-connected timing analysis and the evolution of the flux and spectral
properties using RXTE, Swift, and Chandra observations. We measure a spin
frequency of 0.1185154343(8) s and a frequency derivative of
at MJD 55761.0, in a timing analysis that include
significant non-zero second and third frequency derivatives that we attribute
to timing noise. This corresponds to an estimated spin-down inferred dipole
magnetic field of G, consistent with previous estimates
though still possibly affected by unmodelled noise. We find that the
post-outburst 1--10 keV flux evolution can be characterized by a
double-exponential decay with decay timescales of and
days. We also fit the light curve with a crustal cooling model which suggests
that the cooling results from heat injection into the outer crust. We find that
the hardness-flux correlation observed in magnetar outbursts also characterizes
the outburst of Swift J1822.3-1606. We compare the properties of Swift
J1822.3-1606 with those of other magnetars and their outbursts.Comment: 12 pages, 8 figures, accepted for publication in Ap
A Survey of 56 Mid-latitude EGRET Error Boxes for Radio Pulsars
We have conducted a radio pulsar survey of 56 unidentified gamma-ray sources
from the 3rd EGRET catalog which are at intermediate Galactic latitudes (5 deg.
< |b| < 73 deg.). For each source, four interleaved 35-minute pointings were
made with the 13-beam, 1400-MHz multibeam receiver on the Parkes 64-m radio
telescope. This covered the 95% error box of each source at a limiting
sensitivity of about 0.2 mJy to pulsed radio emission for periods P > 10 ms and
dispersion measures < 50 pc cm-3. Roughly half of the unidentified gamma-ray
sources at |b| > 5 deg. with no proposed active galactic nucleus counterpart
were covered in this survey. We detected nine isolated pulsars and four
recycled binary pulsars, with three from each class being new. Timing
observations suggest that only one of the pulsars has a spin-down luminosity
which is even marginally consistent with the inferred luminosity of its
coincident EGRET source. Our results suggest that population models, which
include the Gould belt as a component, overestimate the number of isolated
pulsars among the mid-latitude Galactic gamma-ray sources and that it is
unlikely that Gould belt pulsars make up the majority of these sources.
However, the possibility of steep pulsar radio spectra and the confusion of
terrestrial radio interference with long-period pulsars (P > 200 ms) having
very low dispersion measures (< 10 pc cm-3, expected for sources at a distance
of less than about 1 kpc) prevent us from strongly ruling out this hypothesis.
Our results also do not support the hypothesis that millisecond pulsars make up
the majority of these sources. Non-pulsar source classes should therefore be
further investigated as possible counterparts to the unidentified EGRET sources
at intermediate Galactic latitudes.Comment: 24 pages, including 4 figures and 3 tables. Accepted for publication
in Ap
Physical activity patterns in a nationally representative sample of adults in Ireland
Original article can be found at: http://journals.cambridge.org/ Copyright - the authors. DOI: 10.1079/PHN2001192Objective To evaluate habitual levels of physical activity in a nationally representative sample of adults in Ireland. Design Cross-sectional survey using a self-administered questionnaire. Usual levels of work, recreational and household activities were evaluated in relation to anthropometric, demographic and socio-economic characteristics. The amount and intensity of all activities were quantified by assigning metabolic equivalents (METS) to each activity. Setting Republic of Ireland and Northern Ireland, 1997–1999. Subjects Random sample of 1379 adults aged 18–64 years. Results Men were approximately twice as active in work and recreational activity (139.7 ± 83.9 METS) as women (68.5 ± 49.8 METS; P 28kg m−2) or obese (BMI > 30kg m−2). Fewer obese subjects reported higher levels of work and leisure activities. However, a higher percentage of obese women reported participation in the higher levels of household activities. Participation rates in recreational activities were low. Walking was the most important leisure activity of both men (41%) and women (60%). In terms of hours per week spent in vigorous physical activity, men were more active than women, professional and skilled non-manual women were more active than women in other social classes, and younger subjects (aged 18–35 years) were more active than older subjects. Conclusions The holistic approach used in the assessment of physical activity in this study has revealed important and subtle differences in the activity patterns of men and women. Failure to fully characterise the respective activity patterns of men and women could lead to ill-informed public health policy aimed at promoting and sustaining lifetime habits of physical activity. The results suggest that simple population-focused programmes to promote physical activity are unlikely to offer the same chance of long-term success as more sensitive and individualised strategies.Peer reviewe
Pulsar magnetic alignment and the pulsewidth-age relation
Using pulsewidth data for 872 isolated radio pulsars we test the hypothesis
that pulsars evolve through a progressive narrowing of the emission cone
combined with progressive alignment of the spin and magnetic axes. The new data
provide strong evidence for the alignment over a time-scale of about 1 Myr with
a log standard deviation of around 0.8 across the observed population. This
time-scale is shorter than the time-scale of about 10 Myr found by previous
authors, but the log standard deviation is larger. The results are inconsistent
with models based on magnetic field decay alone or monotonic counter-alignment
to orthogonal rotation. The best fits are obtained for a braking index
parameter n_gamma approximately equal to 2.3, consistent the mean of the six
measured values, but based on a much larger sample of young pulsars. The
least-squares fitted models are used to predict the mean inclination angle
between the spin and magnetic axes as a function of log characteristic age.
Comparing these predictions to existing estimates it is found that the model in
which pulsars are born with a random angle of inclination gives the best fit to
the data. Plots of the mean beaming fraction as a function of characteristic
age are presented using the best-fitting model parameters.Comment: 13 pages, 11 figures, Accepted for publication in MNRA
- …