2 research outputs found
WOUND HEALING ACTIVITY OF JATROPHA TANJORENSIS LEAVES
Objective: The term âwoundâ is defined as a disruption of normal anatomical structure. Therefore, âhealingâ is the complex and dynamic process that results in the restoration of anatomical continuity and function.
Methods: Albino Wistar rats (150-180 g) of both sexes were selected. The experiment of Wound Healing Activity by Excision Wound Model and Incision Wound Model by the simple ointment B.P., reference standard drug (0.2% w/w nitrofurazone ointment), stigmasterol ointment (0.2% w/w), hexane, chloroform and methanol extract ointments of 3%, 4% and 5% w/w of leaves in Jatropha tanjorensis in simple ointment base (where 3g, 4g and 5 g of the extracts was incorporated in 100 g of simple ointment separately).
Results: The time for wound closure to methanol extract ointment (5% w/w) and stigmasterol (0.2% w/w) was similar to that of standard drug, nitrofurazone ointment (0.2% w/w) 16±2 days in Excision Wound Model. The significant tensile strength at 3%: 4%: 5% w/w methanol extract ointments (p<0.001), followed by chloroform extract and hexane extract. Stigmasterol ointment at 0.2% w/w produced tensile strength comparable with Standard drug, nitrofurazone ointment (0.2% w/w) (p<0.001) in Incision Wound Model.
Conclusion: Juice of the Jatropha plant and the pounded leaves are applied to wounds and refractory ulcers. The juice is very successfully used to treat scabies, eczema and ringworm. The present study proved that the leaves have wound healing activity.
Peer Review History:
Received 5 September 2018; Revised 28 September; Accepted 12 October, Available online 15 November 2018
Academic Editor: Dr. Nuray Arı, Ankara University, Turkiye, [email protected]
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Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 5.5/10
Average Peer review marks at publication stage: 8.0/10
Reviewer(s) detail:
Dr. Mohamed Said Fathy Al-Refaey, University of Sadat City, Menofia, Egypt, [email protected]
Prof. Dr. HĂŒsniye Kayalar, Ege University, Turkey, [email protected]
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Health and lifestyle of Nepalese migrants in the UK
Background: The health status and lifestyle of migrants is often poorer than that of the general
population of their host countries. The Nepalese represent a relatively small, but growing,
immigrant community in the UK, about whom very little is known in term of public health.
Therefore, our study examined the health and lifestyle of Nepalese migrants in the UK.
Methods: A cross-sectional survey of Nepalese migrants in UK was conducted in early 2007 using
a postal, self-administered questionnaire in England and Scotland (n = 312), and telephone
interviews in Wales (n = 15). The total response rate was 68% (327 out of 480). Data were analyzed
to establish whether there are associations between socio-economic and lifestyle factors. A
multivariate binary logistic regression was applied to find out independent effect of personal factors
on health status.
Results: The majority of respondents was male (75%), aged between 30 and 45 (66%), married or
had a civil partner (83%), had university education (47%) and an annual family income (69%) ranging
from ÂŁ5,035 to ÂŁ33,300. More than one third (39%) of the respondents have lived in the UK for 1
to 5 years and approximately half (46%) were longer-term residents. Most (95%) were registered
with a family doctor, but only 38% with a dentist. A low proportion (14%) of respondents smoked
but more than half (61%) consumed alcohol. More than half (57%) did not do regular exercises and
nearly one fourth (23%) of respondents rated their health as poor. Self reported 'good' health
status of the respondents was independently associated with immigration status and doing regular exercise
Conclusion: The self reported health status and lifestyle, health seeking behaviour of Nepalese
people who are residing in UK appears to be good. However, the overall regular exercise and dentist registration was rather poor. Health promotion, especially aimed at Nepalese migrants could help encourage them to exercise regularly and assist them to register with a dentist