114 research outputs found

    Developments at the Advanced Design Technologies Testbed

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    A report presents background and historical information, as of August 1998, on the Advanced Design Technologies Testbed (ADTT) at Ames Research Center. The ADTT is characterized as an activity initiated to facilitate improvements in aerospace design processes; provide a proving ground for product-development methods and computational software and hardware; develop bridging methods, software, and hardware that can facilitate integrated solutions to design problems; and disseminate lessons learned to the aerospace and information technology communities

    The Ursinus Weekly, March 16, 1964

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    Campus Chest set to begin April 6: Shorb and Riley Committee heads • Concert season begun by UC Meistersingers: Group will tour New York state • Noss, theologian & author, will speak here Wednesday • History students will hear Bohl at Wednesday tea • Jeanne Dawson crowned prom queen; Cub and Key taps seven junior men • Three co-eds make US lacrosse team: Great Britain scene of games • Mass meeting of students planned for Wednesday • Group organizes fund campaign; Will defray cost for Ursinus girls on lacrosse team • WSGA approves rule change • Ursinus receives Gulf Oil grant • Psychology Club officers elected • Editorial: Don\u27t walk on that grass; Compulsion won\u27t do it • Journalism grants available • Charles I trial topic of Forum • Letters to the editor • Seek art exchange with Muhlenberg • IRC members hear Barghoorn on Soviet propaganda • Kaffee Klatsch: Determinism, free will • Evening School enrolls 524 • State seeks to annul college charter: Integration irks Mississippians • Agency concert hailed as fine performance • WSGA announces procedure for 1964 election: March 25 petition deadline; Elections will be April 15 • Greek gleanings • Navy offers career program to women • Gwynedd Mercy falls to Ursinus women\u27s 3rd team • Basketball team, coach honored • End of volleyball tourney near • Beaver falls to UC, 61-38 • Kratz caps career • Seals vs. Bock in intramural championship • Netwomen stop Drexel, 5-0https://digitalcommons.ursinus.edu/weekly/1268/thumbnail.jp

    Psychological well-being and cognitive aging in Black, Native American, and White Alzheimer’s Disease Research Center participants

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    Psychological well-being is associated with cognition in later life but has not been examined across diverse populations—including minoritized communities at disproportionately high risk of dementia. Further, most previous work has not been able to examine links between specific facets of psychological well-being and performance within distinct cognitive domains that can capture subclinical impairment. Using a well-characterized sample followed through enrollment in an NIH-funded Alzheimer’s Disease Center, we sought to test these associations within three racial groups at baseline. Participants were N = 529 cognitively unimpaired Black, American Indian/Alaska Native (AI/AN), and white middle-aged and older adults (mean age = 63.6, SD = 8.1, range = 45–88 years) enrolled in the Wisconsin Alzheimer’s Disease Research Center’s Clinical Core. Predictors included validated NIH Toolbox Emotion Battery scales assessing positive affect, general life satisfaction, and meaning and purpose. Outcomes included performance on widely used tests of executive functioning and episodic memory. We conducted race-stratified regression models to assess within-group relationships. Black and AI/AN participants reported lower life satisfaction than white participants. Racial disparities were not observed for positive affect or meaning and purpose scores. Across groups, life satisfaction predicted better executive functioning. Similar associations were observed for positive affect in Black and AI/AN samples but not among whites. In general, well-being measures were not related to performance on tests of episodic memory. Our results highlight well-being as a potentially important determinant of late-life cognitive health, particularly executive functioning, that is modifiable if older adults are connected with appropriate resources and supports. Further, psychological well-being may represent a potent target for brain health interventions tailored for Black and Native communities

    A comparison between the APACHE II and Charlson Index Score for predicting hospital mortality in critically ill patients

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    <p>Abstract</p> <p>Background</p> <p>Risk adjustment and mortality prediction in studies of critical care are usually performed using acuity of illness scores, such as Acute Physiology and Chronic Health Evaluation II (APACHE II), which emphasize physiological derangement. Common risk adjustment systems used in administrative datasets, like the Charlson index, are entirely based on the presence of co-morbid illnesses. The purpose of this study was to compare the discriminative ability of the Charlson index to the APACHE II in predicting hospital mortality in adult multisystem ICU patients.</p> <p>Methods</p> <p>This was a population-based cohort design. The study sample consisted of adult (>17 years of age) residents of the Calgary Health Region admitted to a multisystem ICU between April 2002 and March 2004. Clinical data were collected prospectively and linked to hospital outcome data. Multiple regression analyses were used to compare the performance of APACHE II and the Charlson index.</p> <p>Results</p> <p>The Charlson index was a poor predictor of mortality (C = 0.626). There was minimal difference between a baseline model containing age, sex and acute physiology score (C = 0.74) and models containing either chronic health points (C = 0.76) or Charlson index variations (C = 0.75, 0.76, 0.77). No important improvement in prediction occurred when the Charlson index was added to the full APACHE II model (C = 0.808 to C = 0.813).</p> <p>Conclusion</p> <p>The Charlson index does not perform as well as the APACHE II in predicting hospital mortality in ICU patients. However, when acuity of illness scores are unavailable or are not recorded in a standard way, the Charlson index might be considered as an alternative method of risk adjustment and therefore facilitate comparisons between intensive care units.</p

    Nebraska\u27s Advantage: Productive Agriculture and Bountiful Natural Resources

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    Nebraska\u27s Advantage: Productive Agriculture and Bountiful Natural Resources You can’t talk about healthy production systems and natural resource systems without also thinking about the resilience. We need to harmonize production agriculture in a way that ensures the resilience of our natural ecosystems and rural communities—all while addressing bundles of grand challenges

    Prader-Willi syndrome: A primer for clinicians

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    The advent of sensitive genetic testing modalities for the diagnosis of Prader-Willi syndrome has helped to define not only the phenotypic features of the syndrome associated with the various genotypes but also to anticipate clinical and psychological problems that occur at each stage during the life span. With advances in hormone replacement therapy, particularly growth hormone children born in circumstances where therapy is available are expected to have an improved quality of life as compared to those born prior to growth hormone
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