3 research outputs found
The prevalence, burden and risk factors associated with bronchial asthma in commonwealth of independent states countries (Ukraine, Kazakhstan and Azerbaijan): results of the CORE study
Abstract Background In the Commonwealth of Independent States (CIS) countries epidemiology of Bronchial Asthma (BA) is poorly characterized. The objective of this analysis is to present the prevalence, burden and risk factors associated with BA in the CIS countries as part of the CORE study (Chronic Obstructive REspiratory diseases). Methods A total of 2842 adults (â„18Â years) were recruited (964 in Kiev, Ukraine, 945 in Almaty, Kazakhstan, and 933 in Baku, Azerbaijan) in 2013â2015 during household visits. A two-step cluster random sampling strategy was used. All respondents were interviewed about respiratory symptoms, smoking, medical history. Two definitions were used: (i) âdoctor diagnosed asthmaâ when the respondent reported that he/she had ever been diagnosed with BA by a doctor, (ii) âwheezing symptomsâ (when the respondent reported wheezing at the ATS Respiratory Symptoms Questionnaire during the study) using GINA (2012) recommendations. Chi-square tests were used to assess differences in proportions. Binary logistic regression was used to estimate odds ratios (OR) and 95% CI for association between risk factors and BA. Results Prevalence of âdoctor diagnosed asthmaâ was 12.5, 19.0 and 26.8 per 1000 persons, and prevalence of âwheezing symptomsâ was 74.4, 254.8 and 123.4 per 1000 in Ukraine, Kazakhstan, and Azerbaijan, respectively. Statistically significant relationship with âwheezing symptomsâ was shown for smoking (OR 1.99 (CI 1.22â3.27) in Ukraine, 2.08 (CI 1.54â2.81) in Kazakhstan, 8.01 (CI 5.24â12.24) in Azerbaijan); overweight/obesity (OR: 1.66 (CI 1.02â2.72); 1.94 (CI 1.44â2.62); 1.77 (CI 1.18â2.68), respectively) and dusty work (OR: 3.29 (CI 1.57â6.89); 1.68 (CI 1.18â2.39); 2.36 (CI 1.56â3.59), respectively), and for tuberculosis in Azerbaijan (OR: 10.11 (CI 3.44â29.69)). Co-morbidities like hypertension, cardiovascular diseases, abnormal blood lipids and a history of pneumonia occurred significantly (pâ<â0.05) more frequently in respondents with BA compared to those without BA across all participating countries. Conclusion In CIS countries (Ukraine, Kazakhstan and Azerbaijan) the prevalence of doctor diagnosed asthma was significantly lower compared to prevalence of wheezing symptoms underlining that BA is likely to be underreported in these countries. The information provided in this paper will be helpful for healthcare policy makers in CIS countries to instruct BA management strategies and to allocate healthcare resources accordingly
Additional file 1: of Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the commonwealth of independent states: rationale and design of the CORE study
ĂąÂÂStudy questionnaires used in the CORE studyù contains description of the patient-reported questionnaires used in the CORE study. (DOCX 16 kb