13,104 research outputs found

    Virial Expansion for a Strongly Correlated Fermi Gas

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    Using a high temperature virial expansion, we present a controllable study of the thermodynamics of strongly correlated Fermi gases near the BEC-BCS crossover region. We propose a practical way to determine the expansion coefficients for both harmonically trapped and homogeneous cases, and calculate the third order coefficient b3(T) at finite temperatures T. At resonance, a T-independent coefficient b3, hom -0.29095295 is determined in free space. These results are compared with a recent thermodynamic measurement of Li6 atoms, at temperatures below the degeneracy temperature, and with Monte Carlo simulations

    Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment

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    Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transcriptional responses of Mycobacterium tuberculosis (MTB) in macrophages from wild-type and nitric oxide (NO) synthase 2–deficient mice before and after immunologic activation. The intraphagosomal transcriptome was compared with the transcriptome of MTB in standard broth culture and during growth in diverse conditions designed to simulate features of the phagosomal environment. Genes expressed differentially as a consequence of intraphagosomal residence included an interferon � – and NO-induced response that intensifies an iron-scavenging program, converts the microbe from aerobic to anaerobic respiration, and induces a dormancy regulon. Induction of genes involved in the activation and �-oxidation of fatty acids indicated that fatty acids furnish carbon and energy. Induction of �E-dependent, sodium dodecyl sulfate–regulated genes and genes involved in mycolic acid modification pointed to damage and repair of the cell envelope. Sentinel genes within the intraphagosomal transcriptome were induced similarly by MTB in the lungs of mice. The microbial transcriptome thus served as a bioprobe of the MTB phagosomal environment

    Application of an adaptive tuned vibration absorber on a dual lay-shaft dual clutch transmission powertrain for vibration reduction

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    © 2018 Elsevier Ltd This paper investigates the application of adaptive tuned vibration absorbers (ATVAs) to lightly damped automotive powertrains. To achieve this, a vibration characteristic analysis of a dual lay-shaft dual clutch transmission (DCT)-equipped powertrain system was performed, including a natural frequency evaluation and sensitivity studies. Transient responses due to gear changes and variations of both the gear ratio and engine speed were also evaluated. The results demonstrate that the impact of ATVAs on transient responses during gear changes is minimal, suggesting that these short-duration transients are outside the scope of application for ATVAs. However, as excitation forces originate from the engine, speed has a significant impact on excitation frequency. Furthermore, the gear ratios significantly influence the engine operating range and natural frequency in any particular gear. Therefore, variations of engine speeds and gear ratios are the main influencing factors affecting the dominant excitation frequency. Consequently, the relationships among the system natural frequencies, the dominant external excitation frequency and the inherent frequency of the ATVA are comprehensively studied. By investigating the relationships among the dominant external excitation frequency and system natural frequencies and the system sensitivity analysis results, the installation position, stiffness range and optimal frequency tuning scheme of the ATVA can be determined. The results were applied to a DCT powertrain with continuously changing engine speeds and an ATVA with corresponding variable stiffness, and a frequency tuning scheme is installed on the powertrain. By comparing the simulation results, the effectiveness and reliability of the presented method can be verified

    Colliding AdS gravitational shock waves in various dimensions and holography

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    The formation of marginally trapped surfaces in the off-center collision of two shock waves on AdS_D (with D=4,5,6,7 and 8) is studied numerically. We focus on the case when the two waves collide with nonvanishing impact parameter while the sources are located at the same value of the holographic coordinate. In all cases a critical value of the impact parameter is found above which no trapped surface is formed. The numerical results show the existence of a simple scaling relation between the critical impact parameter and the energy of the colliding waves. Using the isometries of AdS_D we relate the solutions obtained to the ones describing the collision of two waves with a purely holographic impact parameter. This provides a gravitational dual for the head-on collision of two lumps of energy of unequal size.Comment: 25 pages, 11 figures. v2: minor changes, typos corrected. To appear in JHE

    Some Results on the Boundary Control of Systems of Conservation Laws

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    This note is concerned with the study of the initial boundary value problem for systems of conservation laws from the point of view of control theory, where the initial data is fixed and the boundary data are regarded as control functions. We first consider the problem of controllability at a fixed time for genuinely nonlinear Temple class systems, and present a description of the set of attainable configurations of the corresponding solutions in terms of suitable Oleinik-type estimates. We next present a result concerning the asymptotic stabilization near a constant state for general n×nn\times n systems. Finally we show with an example that in general one cannot achieve exact controllability to a constant state in finite time.Comment: 10 pages, 4 figures, conferenc

    Robust Deadbeat Predictive Power Control with a Discrete-Time Disturbance Observer for PWM Rectifiers under Unbalanced Grid Conditions

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    © 2012 IEEE. This paper presents a robust deadbeat predictive power control (DPPC) for pulsewidth modulation (PWM) rectifiers with the consideration of parameter mismatches under unbalanced grid conditions. First, conventional DPPC is modified to extend its application to both ideal and unbalanced grid conditions. Second, a tracking error of the modified DPPC with inaccurate grid-side impedance is analyzed. Third, a discrete-time power disturbance observer (DPDO) is designed to achieve accurate power control with mismatched parameters. The designed DPDO can predict complex power at the next sampling instant and estimate system disturbance simultaneously. Therefore, the DPDO can contribute to eliminate the steady-state tracking error resulting from disturbances caused by inaccurate parameters and compensate one-step delay in digital implementation. Although satisfactory steady-state performance can be obtained with modified DPPC and DPDO, transient performance still deteriorates significantly with an inaccurate value of the grid-side inductance. Thus, an online adaptive method to estimate mismatched inductance is finally developed based on the proposed DPDO. Both DPPC and DPDO are implemented in the stationary reference frame without coordinate transformation. Theoretical analysis confirms that the proposed DPDO can track disturbance without phase lag or magnitude error. Experimental tests and comparative studies with a prior DPPC on a two-level PWM rectifier validate the effectiveness of the proposed scheme

    China’s new growth pattern and its effect on energy demand and greenhouse gas emissions

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    China’s economic transformation and new growth pattern have significant implications for energy demand and greenhouse gas emissions. Using an extended version of a large computable general equilibrium model of China, we explore alternative futures for the Chinese economy and its energy needs over the period from 2015 to 2030. The simulation results show that encouraging household consumption and accelerating economic transition from investment-led to service-led growth will boost China’s economic growth. Capping coal consumption will improve China’s energy consumption structure and reduce greenhouse gas emissions significantly. The simulation exercises imply that, with a well-designed policy, the Chinese government can meet the challenges of strong economic growth, lower carbon emissions, environmental benefits, and energy security. Moreover, the Chinese government’s goal of peaking carbon emissions at 2030 is achievable. Keywords: Dynamic computable general equilibrium model, Economic transition, Energy demand, Greenhouse gas emissions, Economic effect

    Two Major Autoantibody Clusters in Systemic Lupus Erythematosus

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    Systemic lupus erythematosus is a chronic autoimmune disease of complex clinical presentation and etiology and is likely influenced by numerous genetic and environmental factors. While a large number of susceptibility genes have been identified, the production of antibodies against a distinct subset of nuclear proteins remains a primary distinguishing characteristic in disease diagnosis. However, the utility of autoantibody biomarkers for disease sub-classification and grouping remains elusive, in part, because of the difficulty in large scale profiling using a uniform, quantitative platform. In the present study serological profiles of several known SLE antigens, including Sm-D3, RNP-A, RNP-70k, Ro52, Ro60, and La, as well as other cytokine and neuronal antigens were obtained using the luciferase immunoprecipitation systems (LIPS) approach. The resulting autoantibody profiles revealed that 88% of a pilot cohort and 98% of a second independent cohort segregated into one of two distinct clusters defined by autoantibodies against Sm/anti-RNP or Ro/La autoantigens, proteins often involved in RNA binding activities. The Sm/RNP cluster was associated with a higher prevalence of serositis in comparison to the Ro/La cluster (P = 0.0022). However, from the available clinical information, no other clinical characteristics were associated with either cluster. In contrast, evaluation of autoantibodies on an individual basis revealed an association between anti-Sm (P = 0.006), RNP-A (P = 0.018) and RNP-70k (P = 0.010) autoantibodies and mucocutaneous symptoms and between anti-RNP-70k and musculoskeletal manifestations (P = 0.059). Serologically active, but clinically quiescent disease also had a higher prevalence of anti-IFN-α autoantibodies. Based on our findings that most SLE patients belong to either a Sm/RNP or Ro/La autoantigen cluster, these results suggest the possibility that alterations in RNA-RNA-binding protein interactions may play a critical role in triggering and/or the pathogenesis of SLE
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