2,460 research outputs found

    Analysis and Prospect of Research Progress of Health Education Curriculum in China

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    The purpose of this study was twofold: 1) review research results of health education in China and help readers gain a better understanding of the current profiles of research in health education curriculum and 2) provide a theoretical basis for future research in health education curriculum. Using key words such as health education curriculum on Chinese National Knowledge Infrastructure (CNKI), we searched and finally obtained 7287 articles. By using the visual analysis function of CNKI, we also analyzed the overall trend of research in Health Education Curriculum. Review of the articles found that the overall trend of research in health education curriculum in China has been growing since 1987, and has been growing at a steady rate since 2000. At present, the health education curriculum in China mainly consists of two forms: One is as part of physical education and health curriculum. The content generally focus on health knowledge, health habits, health concepts, and sports injury management and prevention in sports; The other form is a separate health education course. Its content generally includes mental health and health habits etc. At present, implementation of health education curriculum in China is mainly influenced by course time, teachers\u27 ability and evaluation mechanism. In the current research field of health education curriculum evaluation, there are more studies related to mental health curriculum evaluation, and the research in this area is mostly based on the construction of evaluation models, and more mature research results have been formed. However, the research on the evaluation of health education curriculum in physical education and health curriculum is relatively weak. Based on the progress of current research, future studies in health education curriculum should be carried out in the following aspects: 1) curriculum content: focusing on epidemic prevention and control theory and practice; 2) curriculum implementation: development of physical education teachers\u27 health knowledge literacy; and 3) curriculum evaluation: participation of multiple subjects

    Avian surface reconstruction in free-flight with application to flight stability analysis of a barn owl and peregrine falcon

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    Birds primarily create and control the forces necessary for flight through changing the shape and orientation of their wings and tail. Their wing geometry is characterised by complex variation in parameters such as camber, twist, sweep and dihedral. To characterise this complexity, a multi-stereo photogrammetry setup was developed for accurately measuring surface geometry in high-resolution during free-flight. The natural patterning of the birds was used as the basis for phase correlation-based image matching, allowing indoor or outdoor use while being non-intrusive for the birds. The accuracy of the method was quantified and shown to be sufficient for characterising the geometric parameters of interest, but with a reduction in accuracy close to the wing edge and in some localized regions. To demonstrate the method's utility, surface reconstructions are presented for a barn owl (Tyto alba) and peregrine falcon (Falco peregrinus) during three instants of gliding flight per bird. The barn owl flew with a consistent geometry, with positive wing camber and longitudinal anhedral. Based on flight dynamics theory this suggests it was longitudinally statically unstable during these flights. The peregrine flew with a consistent glide angle, but at a range of airspeeds with varying geometry. Unlike the barn owl, its glide configuration did not provide a clear indication of longitudinal static stability/instability. Aspects of the geometries adopted by both birds appeared to be related to control corrections and this method would be well suited for future investigations in this area, as well as for other quantitative studies into avian flight dynamics.Flight O1 - original uncompressed tif images for flight O1 of the barn owlO1_images.zipFlight O2 - original uncompressed tif images for flight O2 of the barn owlO2_images.zipFlight O3 - original uncompressed tif images for flight O3 of the barn owlO3_images.zipFlight P1 - original uncompressed tif images for flight P1 of the peregrineP1_images.zipFlight P2 - original uncompressed tif images for flight P2 of the peregrineP2_images.zipFlight P3 - original uncompressed tif images for flight P3 of the peregrineP3_images.zipREADM

    Cold Storage Effects on Fitness of the Whitefly Parasitoids Encarsia sophia and Eretmocerus hayati

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    Successful biological control of the whitefly Bemisia tabaci involves the mass rearing of biocontrol agents in large numbers for field release. Cold storage of the biocontrol agents is often necessary to provide a sufficient number of biocontrol agents during an eventual pest outbreak. In this study, the fitness of two whitefly parasitoids Encarsia sophia Girault and Dodd (Hymenoptera: Aphelinidae) and Eretmocerus hayati Zolnerowich and Rose (Hymenoptera: Aphelinidae) was evaluated under fluctuating cold storage temperatures. The emergence rate of old pupae of either species was not affected when stored at 12, 10, 8 and 6 °C for 1 week. Cold storage had no effect on the longevity of the emerging adult En. sophia except young pupae stored at 4 °C, while Er. hayati was negatively affected after 2 weeks of storage time at all temperatures. Parasitism by adults emerging from older pupae stored at 12 °C for 1 week was equivalent to the control. Combined with the results for the emergence time, we suggest that the old pupal stage of En. sophia and Er. hayati could be stored at 12 and 10 °C, respectively (transferred every 22 h to 26 ± 1 °C for 2 h), for 1 week, with no or little adverse effect.National Natural Science Foundation of China (NSFC) (31672087); National Key Research and Development Project of China (2017YFC1200600, 2016YFC1201200); International Science & Technology Cooperation Program of China (2015DFG32300); Shenzhen Science and Technology Program (KQTD20180411143628272)info:eu-repo/semantics/publishedVersio

    Challenges and Countermeasures of Teachers’ Professional Development from the Perspective of Globalization

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    Under the influence of globalization, the intensification of international competition is in the final analysis the competition of education and talents. Teachers are the main body of teaching activities. Teachers’ professionalization is an important symbol to measure a country’s educational level. At present, the professional development of teachers in China is facing enormous challenges. In terms of concept, system and the allocation and utilization of educational resources, there are great problems. In order to meet the needs of teachers’ professional development in the perspective of globalization, the new era should promote the upgrading of teachers’ professional level from the aspects of renewal of ideas, improvement of system guarantee system, diversified development and integration and distribution of resources

    Avian surface reconstruction in free-flight with application to flight stability analysis of a barn owl and peregrine falcon

    Get PDF
    Birds primarily create and control the forces necessary for flight through changing the shape and orientation of their wings and tail. Their wing geometry is characterised by complex variation in parameters such as camber, twist, sweep and dihedral. To characterise this complexity, a multi-stereo photogrammetry setup was developed for accurately measuring surface geometry in high-resolution during free-flight. The natural patterning of the birds was used as the basis for phase correlation-based image matching, allowing indoor or outdoor use while being non-intrusive for the birds. The accuracy of the method was quantified and shown to be sufficient for characterising the geometric parameters of interest, but with a reduction in accuracy close to the wing edge and in some localized regions. To demonstrate the method's utility, surface reconstructions are presented for a barn owl (Tyto alba) and peregrine falcon (Falco peregrinus) during three instants of gliding flight per bird. The barn owl flew with a consistent geometry, with positive wing camber and longitudinal anhedral. Based on flight dynamics theory this suggests it was longitudinally statically unstable during these flights. The peregrine flew with a consistent glide angle, but at a range of airspeeds with varying geometry. Unlike the barn owl, its glide configuration did not provide a clear indication of longitudinal static stability/instability. Aspects of the geometries adopted by both birds appeared to be related to control corrections and this method would be well suited for future investigations in this area, as well as for other quantitative studies into avian flight dynamics.Flight O1 - original uncompressed tif images for flight O1 of the barn owlO1_images.zipFlight O2 - original uncompressed tif images for flight O2 of the barn owlO2_images.zipFlight O3 - original uncompressed tif images for flight O3 of the barn owlO3_images.zipFlight P1 - original uncompressed tif images for flight P1 of the peregrineP1_images.zipFlight P2 - original uncompressed tif images for flight P2 of the peregrineP2_images.zipFlight P3 - original uncompressed tif images for flight P3 of the peregrineP3_images.zipREADM

    Negative Feedback Regulation of Wnt4 Signaling by EAF1 and EAF2/U19

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    Previous studies indicated that EAF (ELL-associated factor) family members, EAF1 and EAF2/U19, play a role in cancer and embryogenesis. For example, EAF2/U19 may serve as a tumor suppressor in prostate cancer. At the same time, EAF2/U19 is a downstream factor in the non-canonical Wnt 4 signaling pathway required for eye development in Xenopus laevis, and along with EAF1, contributes to convergence and extension movements in zebrafish embryos through Wnt maintenance. Here, we used zebrafish embryos and mammalian cells to show that both EAF1 and EAF2/U19 were up-regulated by Wnt4 (Wnt4a). Furthermore, we found that EAF1 and EAF2/U19 suppressed Wnt4 expression by directly binding to the Wnt4 promoter as seen in chromatin immunoprecipitation assays. These findings indicate that an auto-regulatory negative feedback loop occurs between Wnt4 and the EAF family, which is conserved between zebrafish and mammalian. The rescue experiments in zebrafish embryos showed that early embryonic development required the maintenance of the appropriate levels of Wnt4a through the feedback loop. Others have demonstrated that the tumor suppressors p63, p73 and WT1 positively regulate Wnt4 expression while p21 has the opposite effect, suggesting that maintenance of appropriate Wnt4 expression may also be critical for adult tissue homeostasis and prevention against tumor initiation. Thus, the auto-regulatory negative feedback loop that controls expression of Wnt4 and EAF proteins may play an important role in both embryonic development and tumor suppression. Our findings provide the first convincing line of evidence that EAF and Wnt4 form an auto-regulatory negative feedback loop in vivo

    Conservation and implications of eukaryote transcriptional regulatory regions across multiple species

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    <p>Abstract</p> <p>Background</p> <p>Increasing evidence shows that whole genomes of eukaryotes are almost entirely transcribed into both protein coding genes and an enormous number of non-protein-coding RNAs (ncRNAs). Therefore, revealing the underlying regulatory mechanisms of transcripts becomes imperative. However, for a complete understanding of transcriptional regulatory mechanisms, we need to identify the regions in which they are found. We will call these transcriptional regulation regions, or TRRs, which can be considered functional regions containing a cluster of regulatory elements that cooperatively recruit transcriptional factors for binding and then regulating the expression of transcripts.</p> <p>Results</p> <p>We constructed a hierarchical stochastic language (HSL) model for the identification of core TRRs in yeast based on regulatory cooperation among TRR elements. The HSL model trained based on yeast achieved comparable accuracy in predicting TRRs in other species, e.g., fruit fly, human, and rice, thus demonstrating the conservation of TRRs across species. The HSL model was also used to identify the TRRs of genes, such as p53 or <it>OsALYL1</it>, as well as microRNAs. In addition, the ENCODE regions were examined by HSL, and TRRs were found to pervasively locate in the genomes.</p> <p>Conclusion</p> <p>Our findings indicate that 1) the HSL model can be used to accurately predict core TRRs of transcripts across species and 2) identified core TRRs by HSL are proper candidates for the further scrutiny of specific regulatory elements and mechanisms. Meanwhile, the regulatory activity taking place in the abundant numbers of ncRNAs might account for the ubiquitous presence of TRRs across the genome. In addition, we also found that the TRRs of protein coding genes and ncRNAs are similar in structure, with the latter being more conserved than the former.</p
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