38,137 research outputs found
Structural difference rule for amorphous alloy formation by ion mixing
We formulate a rule which establishes a sufficient condition that an amorphous binary alloy will be formed by ion mixing of multilayered samples when the two constituent metals are of different crystalline structure, regardless of their atomic sizes and electronegativities. The rule is supported by the experimental results we have obtained on six selected binary metal systems, as well as by the previous data reported in the literature. The amorphization mechanism is discussed in terms of the competition between two different structures resulting in frustration of the crystallization process
Ion mixing to produce amorphous Mo-Ru superconducting films
Amorphous Mo55Ru45 alloy films were formed by ion mixing of multilayered samples. The ion mixed films, which contain no metalloid element, show excellent superconducting properties. The measured properties are correlated with the microstructure obtained by both x-ray diffraction and transmission electron microscopy
The classification of traveling wave solutions and superposition of multi-solutions to Camassa-Holm equation with dispersion
Under the traveling wave transformation, Camassa-Holm equation with
dispersion is reduced to an integrable ODE whose general solution can be
obtained using the trick of one-parameter group. Furthermore combining complete
discrimination system for polynomial, the classifications of all single
traveling wave solutions to the Camassa-Holm equation with dispersion is
obtained. In particular, an affine subspace structure in the set of the
solutions of the reduced ODE is obtained. More general, an implicit linear
structure in Camassa-Holm equation with dispersion is found. According to the
linear structure, we obtain the superposition of multi-solutions to
Camassa-Holm equation with dispersion
Holographic Aspects of Fermi Liquids in a Background Magnetic Field
We study the effects of an external magnetic field on the properties of the
quasiparticle spectrum of the class of 2+1 dimensional strongly coupled
theories holographically dual to charged AdS black holes at zero
temperature. We uncover several interesting features. At certain values of the
magnetic field, there are multiple quasiparticle peaks representing a novel
level structure of the associated Fermi surfaces. Furthermore, increasing
magnetic field deforms the dispersion characteristics of the quasiparticle
peaks from non-Landau toward Landau behaviour. At a certain value of the
magnetic field, just at the onset of Landau-like behaviour of the Fermi liquid,
the quasiparticles and Fermi surface disappear.Comment: 18 pages, 10 figures. Revised some of the terminology: changed
non-separable solutions to infinite-sum solution
Nonlocalized modulation of periodic reaction diffusion waves: The Whitham equation
In a companion paper, we established nonlinear stability with detailed
diffusive rates of decay of spectrally stable periodic traveling-wave solutions
of reaction diffusion systems under small perturbations consisting of a
nonlocalized modulation plus a localized perturbation. Here, we determine
time-asymptotic behavior under such perturbations, showing that solutions
consist to leading order of a modulation whose parameter evolution is governed
by an associated Whitham averaged equation
Time-Domain Isolated Phoneme Classification Using Reconstructed Phase Spaces
This paper introduces a novel time-domain approach to modeling and classifying speech phoneme waveforms. The approach is based on statistical models of reconstructed phase spaces, which offer significant theoretical benefits as representations that are known to be topologically equivalent to the state dynamics of the underlying production system. The lag and dimension parameters of the reconstruction process for speech are examined in detail, comparing common estimation heuristics for these parameters with corresponding maximum likelihood recognition accuracy over the TIMIT data set. Overall accuracies are compared with a Mel-frequency cepstral baseline system across five different phonetic classes within TIMIT, and a composite classifier using both cepstral and phase space features is developed. Results indicate that although the accuracy of the phase space approach by itself is still currently below that of baseline cepstral methods, a combined approach is capable of increasing speaker independent phoneme accuracy
Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host
A major gap in understanding infectious diseases is the lack of information about molecular interaction networks between pathogens and the human host. Haemophilus ducreyi causes the genital ulcer disease chancroid in adults and is a leading cause of cutaneous ulcers in children in the tropics. We developed a model in which human volunteers are infected on the upper arm with H. ducreyi until they develop pustules. To define the H. ducreyi and human interactome, we determined bacterial and host transcriptomic and host metabolomic changes in pustules. We found that in vivo H. ducreyi transcripts were distinct from those in the inocula, as were host transcripts in pustule and wounded control sites. Many of the upregulated H. ducreyi genes were found to be involved in ascorbic acid and anaerobic metabolism and inorganic ion/nutrient transport. The top 20 significantly expressed human pathways showed that all were involved in immune responses. We generated a bipartite network for interactions between host and bacterial gene transcription; multiple positively correlated networks contained H. ducreyi genes involved in anaerobic metabolism and host genes involved with the immune response. Metabolomic studies showed that pustule and wounded samples had different metabolite compositions; the top ion pathway involved ascorbate and aldarate metabolism, which correlated with the H. ducreyi transcriptional response and upregulation of host genes involved in ascorbic acid recycling. These data show that an interactome exists between H. ducreyi and the human host and suggest that H. ducreyi exploits the metabolic niche created by the host immune response.IMPORTANCE Dual RNA sequencing (RNA-seq) offers the promise of determining an interactome at a transcriptional level between a bacterium and the host but has yet to be done on any bacterial infection in human tissue. We performed dual RNA-seq and metabolomics analyses on wounded and infected sites following experimental infection of the arm with H. ducreyi Our results suggest that H. ducreyi survives in an abscess by utilizing l-ascorbate as an alternative carbon source, possibly taking advantage of host ascorbic acid recycling, and that H. ducreyi also adapts by upregulating genes involved in anaerobic metabolism and inorganic ion and nutrient transport. To our knowledge, this is the first description of an interaction network between a bacterium and the human host at a site of infection
A Cost-based Optimizer for Gradient Descent Optimization
As the use of machine learning (ML) permeates into diverse application
domains, there is an urgent need to support a declarative framework for ML.
Ideally, a user will specify an ML task in a high-level and easy-to-use
language and the framework will invoke the appropriate algorithms and system
configurations to execute it. An important observation towards designing such a
framework is that many ML tasks can be expressed as mathematical optimization
problems, which take a specific form. Furthermore, these optimization problems
can be efficiently solved using variations of the gradient descent (GD)
algorithm. Thus, to decouple a user specification of an ML task from its
execution, a key component is a GD optimizer. We propose a cost-based GD
optimizer that selects the best GD plan for a given ML task. To build our
optimizer, we introduce a set of abstract operators for expressing GD
algorithms and propose a novel approach to estimate the number of iterations a
GD algorithm requires to converge. Extensive experiments on real and synthetic
datasets show that our optimizer not only chooses the best GD plan but also
allows for optimizations that achieve orders of magnitude performance speed-up.Comment: Accepted at SIGMOD 201
Granular Solid Hydrodynamics
Granular elasticity, an elasticity theory useful for calculating static
stress distribution in granular media, is generalized to the dynamic case by
including the plastic contribution of the strain. A complete hydrodynamic
theory is derived based on the hypothesis that granular medium turns
transiently elastic when deformed. This theory includes both the true and the
granular temperatures, and employs a free energy expression that encapsulates a
full jamming phase diagram, in the space spanned by pressure, shear stress,
density and granular temperature. For the special case of stationary granular
temperatures, the derived hydrodynamic theory reduces to {\em hypoplasticity},
a state-of-the-art engineering model.Comment: 42 pages 3 fi
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