Ultrasound and clinical preoperative characteristics for discrimination between ovarian metastatic colorectal cancer and primary ovarian cancer: A case-control study

The aim of this study was to describe the clinical and sonographic features of ovarian metastases originating from colorectal cancer (mCRC), and to discriminate mCRC from primary ovarian cancer (OC). We conducted a multi-institutional, retrospective study of consecutive patients with ovarian mCRC who had undergone ultrasound examination using the International Ovarian Tumor Analysis (IOTA) terminology, with the addition of evaluating signs of necrosis and abdominal staging. A control group included patients with primary OC. Clinical and ultrasound data, subjective assessment (SA), and an assessment of different neoplasias in the adnexa (ADNEX) model were evaluated. Fisher's exact and Student's t-tests, the area under the receiver-operating characteristic curve (AUC), and classification and regression trees (CART) were used to conduct statistical analyses. In total, 162 patients (81 with OC and 81 with ovarian mCRC) were included. None of the patients with OC had undergone chemotherapy for CRC in the past, compared with 40% of patients with ovarian mCRC (p < 0.001). The ovarian mCRC tumors were significantly larger, a necrosis sign was more frequently present, and tumors had an irregular wall or were fixed less frequently; ascites, omental cake, and carcinomatosis were less common in mCRC than in primary OC. In a subgroup of patients with ovarian mCRC who had not undergone treatment for CRC in anamnesis, tumors were larger, and had fewer papillations and more locules compared with primary OC. The highest AUC for the discrimination of ovarian mCRC from primary OC was for CART (0.768), followed by SA (0.735) and ADNEX calculated with CA-125 (0.680). Ovarian mCRC and primary OC can be distinguished based on patient anamnesis, ultrasound pattern recognition, a proposed decision tree model, and an ADNEX model with CA-125 levels

Adolescents' Commitment to Developing Talent: The Role of Peers in Continuing Motivation for Sports and the Arts

The role of peer relationships in supporting or hindering adolescents' talent development has received little research attention, despite the importance of peers in adolescents' lives. We conducted semi-structured in-depth interviews with 41 adolescents talented in sports or the arts, and their parents, to investigate (a) the role of peer relationships in adolescents' continued involvement in their talent activities, (b) possible differences in this role by activity domain, and (c) possible gender differences. Thematic analysis indicated that peers typically played a positive function in supporting the continued involvement of talented adolescents in their talent activities. There were differences in opportunities for peer relationships and social satisfaction between in-school and out-of school activities, but not between activity domains. Both males and females mentioned equally social benefits of such involvement. However, females mentioned receiving negative peer attention more frequently than males, and more often cited social dissatisfaction as a significant contributor to decreased involvement or quitting.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45286/1/10964_2004_Article_411240.pd

Sex Differences in Self-Concept and Symptoms of Depression During the Transition to College

In an investigation of sex differences in adaptation to college, real and ideal self-concept and symptoms of depression were studied longitudinally in a sample of 287 students. Survey data were collected at a summer orientation and one semester into freshman year. No sex differences in self-concept were found before college, but males' real self-concept became more positive over the transition. Females were more depressed than males at both times, although depressive symptom scores increased in both sexes. Real self-concept scores were negatively correlated with depressive symptoms in both sexes at both times, while the discrepancy between real and ideal self-concepts was positively correlated with depressive symptoms among females before college and in both sexes midway through freshman year. A one-year follow-up revealed that females' real self-concept scores increased to match those of males by mid-sophomore year. These sex differences are discussed in relation to psychological development during adolescence.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45284/1/10964_2004_Article_411446.pd

The Influence of Jahn-Teller Effect on Magnetic Properties of Fe-Based Semimagnetic Semiconductors

We report results of calculations of magnetic properties (specific heat, magnetization) of Fe-based Semimagnetic Semiconductors including Jahn-Teller coupling between Fe electronic states and phonons

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