64 research outputs found
Reconstructing 800 years of summer temperatures in Scotland from tree rings
We thank The Carnegie Trust for the Universities of Scotland for providing funding for Miloš Rydval’s PhD. The Scottish pine network expansion has been an ongoing task since 2007 and funding must be acknowledged to the following projects: EU project ‘Millennium’ (017008-2), Leverhulme Trust project ‘RELiC: Reconstructing 8000 years of Environmental and Landscape change in the Cairngorms (F/00 268/BG)’ and the NERC project ‘SCOT2K: Reconstructing 2000 years of Scottish climate from tree rings (NE/K003097/1)’.This study presents a summer temperature reconstruction using Scots pine tree-ring chronologies for Scotland allowing the placement of current regional temperature changes in a longer-term context. ‘Living-tree’ chronologies were extended using ’subfossil’ samples extracted from nearshore lake sediments resulting in a composite chronology > 800 years in length. The North Cairngorms (NCAIRN) reconstruction was developed from a set of composite blue intensity high-pass and ring-width low-pass chronologies with a range of detrending and disturbance correction procedures. Calibration against July-August mean temperature explains 56.4% of the instrumental data variance over 1866-2009 and is well verified. Spatial correlations reveal strong coherence with temperatures over the British Isles, parts of western Europe, southern Scandinavia and northern parts of the Iberian Peninsula. NCAIRN suggests that the recent summer-time warming in Scotland is likely not unique when compared to multi-decadal warm periods observed in the 1300s, 1500s, and 1730s, although trends before the mid-16th century should be interpreted with some caution due to greater uncertainty. Prominent cold periods were identified from the 16th century until the early 1800s – agreeing with the so-called Little Ice Age observed in other tree-ring reconstructions from Europe - with the 1690s identified as the coldest decade in the record. The reconstruction shows a significant cooling response one year following volcanic eruptions although this result is sensitive to the datasets used to identify such events. In fact, the extreme cold (and warm) years observed in NCAIRN appear more related to internal forcing of the summer North Atlantic Oscillation.Publisher PDFPeer reviewe
A polygenic burden of rare disruptive mutations in schizophrenia.
Schizophrenia is a common disease with a complex aetiology, probably involving multiple and heterogeneous genetic factors. Here, by analysing the exome sequences of 2,536 schizophrenia cases and 2,543 controls, we demonstrate a polygenic burden primarily arising from rare (less than 1 in 10,000), disruptive mutations distributed across many genes. Particularly enriched gene sets include the voltage-gated calcium ion channel and the signalling complex formed by the activity-regulated cytoskeleton-associated scaffold protein (ARC) of the postsynaptic density, sets previously implicated by genome-wide association and copy-number variation studies. Similar to reports in autism, targets of the fragile X mental retardation protein (FMRP, product of FMR1) are enriched for case mutations. No individual gene-based test achieves significance after correction for multiple testing and we do not detect any alleles of moderately low frequency (approximately 0.5 to 1 per cent) and moderately large effect. Taken together, these data suggest that population-based exome sequencing can discover risk alleles and complements established gene-mapping paradigms in neuropsychiatric disease
Tree-rings and climate - Standardization, proxy-development, and Fennoscandian summer temperature history
Instrumental meteorological observation are too short for trying to estimate
climate change and variability on multi-decadal and centennial time-scales, and when
trying to evaluate the response of the climate system to human influence, such as
raised concentrations of green house gases (GHG), altered land-use, black carbon etc.
To access information about the climate system predating instrumental observations,
reliable proxy records (natural archives) are necessary. These proxies include for
example tree rings, ice cores, fossil pollen, ocean sediments, corals and historical
documentary data.
Tree rings is one of the most widely used proxy for high-resolution growing season
temperature reconstructions during the last millennium, and in Fennoscandia some of
the best-calibrated records in the world exist. Yet, in this available body of work,
there is limited homogeneity on decadal to centennial scales. Since this tree-ring data
is targeting growing-season temperatures and growing-season temperatures in this
region are very well correlated on annual to decadal scales this is unexpected. This
thesis is concerned with trying to address this issue by 1) developing existing
standardization-tools in order to display centennial scale variability and at the same
time reduce noise arising from internal and external disturbances and mismatches in
actual growth trends compared to the expected growth trend. 2) By developing the
new un-exploited ΔDensity and ΔBlue Intensity proxies (the difference between the
latewood and earlywood for density and blue intensity respectively) to act as
complement or quality control to the established maximum latewood density (MXD)
which is the state of the art proxy for high latitude temperature reconstructions, and
also to the Blue Intensity measurement scheme, that potentially could be an
inexpensive complement to the radiodensitometric methodology.
Results showed that using the Δ parameter for both density and Blue Intensity, give
added value in a more focused annual scale summer temperature signal, and an
improved coherence between different chronologies on decadal to centennial scales.
Methodological protocols such as data analysis and standardization seem to be critical
when trying to attain adequate low-frequency signals from tree-ring data. A more
coherent view of the summer temperature history for the last 900 years in
Fennoscandia is provided using the methodological improvements outlined in this
thesis. Future challenges include trying to extend this excellent network back in time
to not only cover the Little Ice Age (1450-1900 CE) but also to cover the debated
Medieval Climate Anomaly (850-1250 CE)
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