Lasing on nonlinear localized waves in curved geometry

The use of geometrical constraints opens many new perspectives in photonics and in fundamental studies of nonlinear waves. By implementing surface structures in vertical cavity surface emitting lasers as manifolds for curved space, we experimentally study the impacts of geometrical constraints on nonlinear wave localization. We observe localized waves pinned to the maximal curvature in an elliptical-ring, and confirm the reduction in the localization length of waves by measuring near and far field patterns, as well as the corresponding dispersion relation. Theoretically, analyses based on a dissipative model with a parabola curve give good agreement remarkably to experimental measurement on the transition from delocalized to localized waves. The introduction of curved geometry allows to control and design lasing modes in the nonlinear regime.Comment: 6 pages, 6 figure

A Novel Printed Folded Dipole Antenna Used for Modem RFID System

For the minimization of RFID tag antenna, we designed a printed folded dipole antenna working at 2.4 GHz. And a mirror compensation technology was introduced to improve the radiation feature of antenna with better return loss characteristic and directivity. The simulated results show that when VSWR (Vertical Standing Wave Ratio) is less than 2, the antenna bandwidth is up to 0.39 GHz absolutely and to 15.48% relatively. Considering engineering processes, the influences of dielectric constant epsilon(r), board thickness, folding degree and other parameters on the properties of this antenna are particularly studied. On the basis, a dual-frequency folded dipole antenna is proposed, which can work in two main frequency for RFED system, i.e. 915 MHz and 2.4 GHz. Moreover, an antenna sample made on this novel structure has been tested and the results show that the bandwidth of antenna is improved in further, along with hemisphere directional radiation characteristics

The microstrip antenna with PBG used for 3G system

Aiming at the request of the antenna used for 3G system, we first analyze the characteristics of microstrip antenna and design methods of size structure, and then design the microstrip antenna with PBG by using MWO. The detailed analysis inquiries into the influence on the reflection coefficient S-11 by key parameters, such as the length of PBG sides, the structural periodicity of PBG, the feeding point of antenna, the dielectric constant and thickness of circuit board have been studied. Finally, the design principles and advantages of the microstrip antenna with PBG are summarized

Inhibition of cyclin-dependent kinase 7 down-regulates yes-associated protein expression in mesothelioma cells.

Cyclin-dependent kinase 7 (CDK7) is a protein kinase that plays a major role in transcription initiation. Yes-associated protein (YAP) is a main effector of the Hippo/YAP signalling pathway. Here, we investigated the role of CDK7 on YAP regulation in human malignant pleural mesothelioma (MPM). We found that in microarray samples of human MPM tissue, immunohistochemistry staining showed correlation between the expression level of CDK7 and YAP (n = 70, r = .513). In MPM cells, CDK7 expression level was significantly correlated with GTIIC reporter activity (r = .886, P = .019). Inhibition of CDK7 by siRNA decreased the YAP protein level and the GTIIC reporter activity in the MPM cell lines 211H, H290 and H2052. Degradation of the YAP protein was accelerated after CDK7 knockdown in 211H, H290 and H2052 cells. Inhibition of CDK7 reduced tumour cell migration and invasion, as well as tumorsphere formation ability. Restoration of the CDK7 gene rescued the YAP protein level and GTIIC reporter activity after siRNA knockdown in 211H and H2052 cells. Finally, we performed a co-immunoprecipitation analysis using an anti-YAP antibody and captured the CDK7 protein in 211H cells. Our results suggest that CDK7 inhibition reduces the YAP protein level by promoting its degradation and suppresses the migration and invasion of MPM cells. Cyclin-dependent kinase 7 may be a promising therapeutic target for MPM

A Novel Ceramic Fractal Antenna for Modern RFID System

A novel double bands ceramic fractal antenna working at 2.4 GHz and 5.8 GHz is designed for the minimization requirement of RFID tag antenna. The simulated results show that when VSWR (Vertical Standing Wave Ratio) is less than 2, the antenna absolute bandwidths are up to 0.39 GHz and 1.85 GHz in 2.4 GHz and 5.8 GHz respectively, with relative bandwidths up to 15.20% and 35.82% respectively,. Considering engineering processes, the influence of dielectric constant F, and substrate thickness are studied in detail. At last we proposed an optimized antenna with duel fractal structure, which can cover all primary frequency bands of RFID system, from 2.17 GHz to 7.05 GHz

A Ceramic Spiral Antenna used for Modern RFID System

For the requirements of wideband RFID antenna, we designed a ceramic spiral antenna working at 915 MHz. The simulated results show that when VSWR (Vertical Standing Wave Ratio) is less than 2, the antenna bandwidth is up to 1.22 GHz (0.57 similar to 1.79 GHz) absolutely and to 133.21% relatively at the central frequency of 0.9 GHz. Considering engineering processes, the influence of dielectric constant epsilon(r) and thickness of circuit board are particularly studied. On this basis, a dual-frequency ceramic spiral antenna is proposed, which can work with respect to all the main frequencies of RFID system, i.e. 915 MHz and 2.4 GHz

Suppressing Decoherence in Quantum Plasmonic Systems by Spectral Hole Burning Effect

Quantum plasmonic systems suffer from significant decoherence due to the intrinsically large dissipative and radiative dampings. Based on our quantum simulations via a quantum tensor network algorithm, we numerically demonstrate the mitigation of this restrictive drawback by hybridizing a plasmonic nanocavity with an emitter ensemble with inhomogeneously-broadened transition frequencies. By burning two narrow spectral holes in the spectral density of the emitter ensemble, the coherent time of Rabi oscillation for the hybrid system is increased tenfold. With the suppressed decoherence, we move one step further in bringing plasmonic systems into practical quantum applications

Local Gene Transfer of OPG Prevents Joint Damage and Disease Progression in Collagen-Induced Arthritis

This study examined the influence of osteoprotegerin (OPG) gene transfer on a murine collagen-induced arthritis model. A single periarticular injection of AAV-OPG or AAV-LacZ on the arthritic paw successfully incorporated the exogenous gene to the local tissue and resulted in marked transgene expression in the joint homogenate for at least three weeks. Clinical disease scores were significantly improved in OPG treated mice starting at 28-day post-treatment (P<0.05). Histological assessment demonstrated that OPG gene transfer dramatically protected mice from erosive joint changes compared with LacZ controls (P<0.05), although treatment appeared less effective on the local inflammatory progress. MicroCT data suggested significant protection against subchondral bone mineral density changes in OPG treated CIA mice. Interestingly, mRNA expressions of IFN-g and MMP3 were noticeably diminished following OPG gene transfer. Overall, gene transfer of OPG effectively inhibited the arthritis-associated periarticular bone erosion and preserved the architecture of arthritic joints, and the study provides evidence that the cartilage protection of the OPG gene therapy may be associated with the down-regulation of MMP3 expression

Unshielded Magnetocardiography in Clinical Practice: Detection of Myocardial Damage in CAD Patients and in Patients Recovered from COVID-19

The chapter deals with magnetocardiography—a specific section of electrocardiography, which is designed to analyze the magnetic component of the electromagnetic field of the heart. Magnetocardiography is described as clinical information technology (IT), i.e., a set of methods, software, and hardware combined into a technological chain, the product of which is an automated diagnostic report. There are several examples of magnetocardiographic information technology implementation in clinical routine, aiming to register and evaluate subtle changes in the electromagnetic field of the heart for early diagnosis of the most common and dangerous heart diseases, especially coronary heart disease. It is shown that new metrics of analysis of spatial structure of 2D and 3D magnetocardiographic maps of current density distribution allow diagnosis with high accuracy of various forms of myocardial ischemia as well as myocardial damage in patients, recently recovered from COVID-19