338 research outputs found
No spin-localization phase transition in the spin-boson model without local field
We explore the spin-boson model in a special case, i.e., with zero local
field. In contrast to previous studies, we find no possibility for quantum
phase transition (QPT) happening between the localized and delocalized phases,
and the behavior of the model can be fully characterized by the even or odd
parity as well as the parity breaking, instead of the QPT, owned by the ground
state of the system. Our analytical treatment about the eigensolution of the
ground state of the model presents for the first time a rigorous proof of
no-degeneracy for the ground state of the model, which is independent of the
bath type, the degrees of freedom of the bath and the calculation precision. We
argue that the QPT mentioned previously appears due to unreasonable treatment
of the ground state of the model or of the infrared divergence existing in the
spectral functions for Ohmic and sub-Ohmic dissipations.Comment: 5 pages, 1 figure. Comments are welcom
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Five-S-isotope evidence of two distinct mass-independent sulfur isotope effects and implications for the modern and Archean atmospheres.
The signature of mass-independent fractionation of quadruple sulfur stable isotopes (S-MIF) in Archean rocks, ice cores, and Martian meteorites provides a unique probe of the oxygen and sulfur cycles in the terrestrial and Martian paleoatmospheres. Its mechanistic origin, however, contains some uncertainties. Even for the modern atmosphere, the primary mechanism responsible for the S-MIF observed in nearly all tropospheric sulfates has not been identified. Here we present high-sensitivity measurements of a fifth sulfur isotope, stratospherically produced radiosulfur, along with all four stable sulfur isotopes in the same sulfate aerosols and a suite of chemical species to define sources and mechanisms on a field observational basis. The five-sulfur-isotope and multiple chemical species analysis approach provides strong evidence that S-MIF signatures in tropospheric sulfates are concomitantly affected by two distinct processes: an altitude-dependent positive 33S anomaly, likely linked to stratospheric SO2 photolysis, and a negative 36S anomaly mainly associated with combustion. Our quadruple stable sulfur isotopic measurements in varying coal samples (formed in the Carboniferous, Permian, and Triassic periods) and in SO2 emitted from combustion display normal 33S and 36S, indicating that the observed negative 36S anomalies originate from a previously unknown S-MIF mechanism during combustion (likely recombination reactions) instead of coal itself. The basic chemical physics of S-MIF in both photolytic and thermal reactions and their interplay, which were not explored together in the past, may be another ingredient for providing deeper understanding of the evolution of Earth's atmosphere and life's origin
Implications of regional surface ozone increases on visibility degradation in southeast China
Long-term visibility (1968ā2010) and air pollutant (1984ā2010) data records in Hong Kong reveal that the occurrence of reduced visibility (RV, defined as the percentage of hours per month with visibility below 8 km in the absence of rain, fog, mist or relative humidity above 95%) in southeast China has increased significantly in the last four decades. The most pronounced rate of increase was observed after 1990 (nine times higher than that before 1990), when notable increases in surface ozone (O3) levels were simultaneously observed (1.06 Āµg mā3 per yr). The greatest increases in RV, and in O3, NO2 and SO2 concentrations are coincident in the autumn (1.47, 0.20 and 0.45 Āµg mā3 per yr respectively), when southeast China is strongly influenced by regional O3 formation and accumulation due to continental outflow of pollution from the east China coast under favourable meteorological conditions. Multiple regression revealed that the RV percentage correlated well (p<0.05) with NO2 and NO x in the 1980s, and with NO2, SO2 and O3 after the 1990s, suggesting that there have been changes in the predominant factors causing visibility degradation. In order to elucidate the reasons for these changes, the results were integrated with data from previous research. Possible impacts of elevated O3 on secondary particle formation and their effects on visibility degradation and aerosol radiative forcing in an oxidant-enhanced southeast China are highlighted. Other factors potentially leading to visibility degradation, such as ship emissions and biomass burning, are also discussed
Corrigendum to āBiological Evaluation of the Effect of Galvanic Coupling Intrabody Communication on Human Skin Fibroblast Cellsā
Influences of commuting mode, air conditioning mode and meteorological parameters on fine particle (PM2.5) exposure levels in traffic microenvironments
With the aim of determining the impacts of various factors on commuter exposure to fine particulate matter (PM2.5), a series of field studies were carried out to measure commuter exposure to PM2.5 on six major commuting modes (in-cabin mode: bus, taxi and metro; on-roadway mode: walking, bicycle and motorcycle) in a highly industrialized city in the Pearl River Delta, China. The results showed that the exposure level was greatly influenced by the commuter mode, with the on-roadway mode showing a higher PM2.5 concentration (76 Ī¼g/m3). An experiment with the taxi mode suggested that the use of air-conditioning can effectively reduce exposure levels in most cases (by at least 83%). Apart from traffic-related emissions, ambient PM2.5 concentration also had important impacts on exposure levels in most commuting modes, which was further ascertained by the seasonal variations in exposure levels and their significant correlations (p < 0.05) with meteorological parameters (temperature, relative humidity, wind speed and direction). The results of a General Linear Model analysis show that temperature, traffic mode and wind speed were significant factors that explained 27.3% of variability for the in-cabin mode, while relative humidity and wind speed were the significant determinants for the on-roadway mode, which contributed 14.1% of variability. In addition, wind direction was also an important determinant for both in-cabin and on-roadway modes. This study has some valuable implications that can help commuters to adopt appropriate travel behavior to reduce their personal exposure to such pollutants
Non-vitamin K Antagonist Oral Anticoagulants and Cognitive Impairment in Atrial Fibrillation: Insights From the Meta-Analysis of Over 90,000 Patients of Randomized Controlled Trials and Real-World Studies
Background: The relationship between the use of non-vitamin K antagonist oral anticoagulants (NOACs) and the impairment of cognition in atrial fibrillation (AF) remains unknown.Methods: A comprehensive database search of Medline, Embase, Cochrane Library databases, and ClinicalTrials.gov Website was performed for randomized controlled trials (RCTs) reporting cognitive impairment events and observational nationwide database studies reporting adjusted hazard ratio (HR) in AF patients with NOACs. The primacy outcome was a composite of any cognitive impairment. Summary of HRs and 95% confidence intervals (95%CI) were calculated using the fixed- and random-effects models. Subgroup analyses were undertaken according to the individual NOACs, study types, and duration of follow-up.Results: Finally, eight studies including 97,595 patients (77,643 patients in 6 RCTs and 19,952 patients in 2 observational database studies) met the inclusion criteria, among which 55,337 (56.7%) patients were receiving NOACs and 42,258 (43.3%) patients were receiving vitamin K Antagonists (VKAs) or acetylsalicylic acid. The results showed a borderline significant association between the use of NOACs and the lower risk of cognitive impairment when compared with VKAs/ acetylsalicylic acid (HR: 0.80, 95%CI: 0.63ā0.98 for fixed-effects model; HR: 0.77; 95%CI: 0.53ā1.01 for random-effects model), with no significant heterogeneity between the studies (I2 = 39.4%, P = 0.12). The results were consistent across the key subgroups (Pinteraction > 0.05 for each).Conclusions: The results indicated that the use of NOACs might lower the tendency on the risk of cognitive impairment in comparison to VKAs/acetylsalicylic acid, and further RCTs and real-world studies are required on an urgent basis to obtain a robust result
Hyperbaric oxygen upregulates cochlear constitutive nitric oxide synthase
<p>Abstract</p> <p>Background</p> <p>Hyperbaric oxygen therapy (HBOT) is a known adjuvant for treating ischemia-related inner ear diseases. Controversies still exist in the role of HBOT in cochlear diseases. Few studies to date have investigated the cellular changes that occur in inner ears after HBOT. Nitric oxide, which is synthesized by nitric oxide synthase (NOS), is an important signaling molecule in cochlear physiology and pathology. Here we investigated the effects of hyperbaric oxygen on eardrum morphology, cochlear function and expression of NOS isoforms in cochlear substructures after repetitive HBOT in guinea pigs.</p> <p>Results</p> <p>Minor changes in the eardrum were observed after repetitive HBOT, which did not result in a significant hearing threshold shift by tone burst auditory brainstem responses. A differential effect of HBOT on the expression of NOS isoforms was identified. Upregulation of constitutive NOS (nNOS and eNOS) was found in the substructures of the cochlea after HBOT, but inducible NOS was not found in normal or HBOT animals, as shown by immunohistochemistry. There was no obvious DNA fragmentation present in this HBOT animal model.</p> <p>Conclusions</p> <p>The present evidence indicates that the customary HBOT protocol may increase constitutive NOS expression but such upregulation did not cause cell death in the treated cochlea. The cochlear morphology and auditory function are consequently not changed through the protocol.</p
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