Facilidades e dificuldades da família no cuidado à criança com paralisia cerebral

Pesquisa qualitativa, exploratória, descritiva, que objetivou apreender as facilidades e as dificuldades da família nocuidado às crianças com paralisia cerebral. Os dados foram coletados com sete famílias, entre março e abril de 2009,por meio de entrevista semiestruturada. A análise seguiu os princípios da interpretação temática. As dificuldades sãomais evidenciadas que as facilidades e trazem repercussões nas atividades de vida diária. Lidar com convulsões dedifícil controle, espasticidade, alterações de tônus postural, presença de reflexos primitivos implicam na complexidadeem tarefas simples, como alimentação, banho, locomoção, pois as crianças ficam, cada dia, mais dependentes doscuidadores. Com o tempo, as dificuldades cedem lugar à rotina e à adaptação à vida diária da criança. Estreitarrelações com a família, melhorando o vínculo e desenvolvendo ações de qualidade e integrais, promovem o bemestarda família/criança com paralisia cerebral

Effect of a toxic protein isolated from Zea mays seeds on the development and survival of the cowpea weevil, Callosobruchus maculatus

A new toxic glycoprotein (Zeatoxin) has been isolated from Zea mays and sequenced. The toxin is a single polypeptide chain, with Mr of 10 kDa. Zeatoxin was not digested by a mixture of pepsin and papain or by midgut preparations of C. maculatus. A diet of artificial seeds (final concentration, 0.25%) was lethal to 50% of C. maculatus. These results show that Zeatoxin is a new toxic glycoprotein to C. maculatus. A search in the database indicated that the N-terminal sequence show no homology to any other known protein.7422523

Childhood depression: a systematic review

Nádia Nara Rolim Lima,1 Vânia Barbosa do Nascimento,1 Sionara Melo Figueiredo de Carvalho,1 Luiz Carlos de Abreu,1,3 Modesto Leite Rolim Neto,2 Aline Quental Brasil,2 Francisco Telésforo Celestino Junior,2 Gislene Farias de Oliveira,2 Alberto Olavo Advíncula Reis3 1Programa de Pós-graduação em Ciências da Saúde, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil; 2Departamento de Medicina. Universidade Federal do Ceará, UFC, Barbalha, Ceará, Brazil; 3Departamento de Saúde Materno Infantil, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil Abstract: As an important public health issue, childhood depression deserves special attention, considering the serious and lasting consequences of the disease to child development. Taking this into consideration, the present study was based on the following question: what practical contributions to clinicians and researchers does the current literature on childhood depression have to offer? The objective of the present study was to conduct a systematic review of articles regarding childhood depression. To accomplish this purpose, a systematic review of articles on childhood depression, published from January 1, 2010 to November 24, 2012, on MEDLINE and SciELO databases was carried out. Search terms were “depression” (medical subject headings [MeSH]), “child” (MeSH), and "childhood depression" (keyword). Of the 180 retrieved studies, 25 met the eligibility criteria. Retrieved studies covered a wide range of aspects regarding childhood depression, such as diagnosis, treatment, prevention and prognosis. Recent scientific literature regarding childhood depression converge to, directly or indirectly, highlight the negative impacts of depressive disorders to the children's quality of life. Unfortunately, the retrieved studies show that childhood depression commonly grows in a background of vulnerability and poverty, where individual and familiar needs concerning childhood depression are not always taken into consideration. In this context, this review demonstrated that childhood-onset depression commonly leads to other psychiatric disorders and co-morbidities. Many of the retrieved studies also confirmed the hypothesis that human resources (eg, health care team in general) are not yet adequately trained to address childhood depression. Thus, further research on the development of programs to prepare health care professionals to deal with childhood depression is needed, as well as complementary studies, with larger and more homogeneous samples, centered on prevention and treatment of childhood depression. Keywords: child, depression, depressive disorder, mental health, mental disorder