Estimation of tunnel blockage from wall pressure signatures: A review and data correlation

A method is described for estimating low speed wind tunnel blockage, including model volume, bubble separation and viscous wake effects. A tunnel-centerline, source/sink distribution is derived from measured wall pressure signatures using fast algorithms to solve the inverse problem in three dimensions. Blockage may then be computed throughout the test volume. Correlations using scaled models or tests in two tunnels were made in all cases. In many cases model reference area exceeded 10% of the tunnel cross-sectional area. Good correlations were obtained regarding model surface pressures, lift drag and pitching moment. It is shown that blockage-induced velocity variations across the test section are relatively unimportant but axial gradients should be considered when model size is determined

Theoretical and experimental study of a new method for prediction of profile drag of airfoil sections

Theoretical and experimental studies are described which were conducted for the purpose of developing a new generalized method for the prediction of profile drag of single component airfoil sections with sharp trailing edges. This method aims at solution for the flow in the wake from the airfoil trailing edge to the large distance in the downstream direction; the profile drag of the given airfoil section can then easily be obtained from the momentum balance once the shape of velocity profile at a large distance from the airfoil trailing edge has been computed. Computer program subroutines have been developed for the computation of the profile drag and flow in the airfoil wake on CDC6600 computer. The required inputs to the computer program consist of free stream conditions and the characteristics of the boundary layers at the airfoil trailing edge or at the point of incipient separation in the neighborhood of airfoil trailing edge. The method described is quite generalized and hence can be extended to the solution of the profile drag for multi-component airfoil sections

Ground simulation and tunnel blockage for a jet-flapped, basic STOL model tested to very high lift coefficients

Ground effects experiments and large/small-tunnel interference studies were carried out on a model with a 20-inch (50.8 cm) span wing. The wing, which includes a highly deflected knee-blown flap can be fitted with unflapped tips and slats. A low-mounted tailplane can be fitted to the aft fuselage. Three-component balance meaurements, made with a fixed ground equipped with a single boundary-layer blowing slot, were compared with datum, moving-ground results. Good comparisons were obtained up to model blowing momentum coefficients of approximately two, after which the particular floor blowing settings used proved insufficient to prevent floor separation in the vicinity of the model. Skin friction measurements, taken routinely along the floor centerline, proved invaluable during the analysis of results, and their use is recommended as input to determination of floor BLC setting. A careful investigation was made of pitching moments, including tail-on, close-to-ground cases, with favorable results. Drag proved the most sensitive to the change from a moving to the boundary-layer controlled ground

Experimental study of the separating confluent boundary-layer. Volume 2: Experimental data

An experimental low speed study of the separating confluent boundary layer on a NASA GAW-1 high lift airfoil is described. The airfoil was tested in a variety of high lift configurations comprised of leading edge slat and trailing edge flap combinations. The primary test instrumentation was a two dimensional laser velocimeter (LV) system operating in a backscatter mode. Surface pressures and corresponding LV derived boundary layer profiles are given in terms of velocity components, turbulence intensities and Reynolds shear stresses as characterizing confluent boundary layer behavior up to and beyond stall. LV derived profiles and associated boundary layer parameters and those obtained from more conventional instrumentation such as pitot static transverse, Preston tube measurements and hot-wire surveys are compared

Models of Distorted and Evolving Dark Matter Halos

We investigate the ability of basis function expansions to reproduce the evolution of a Milky Way-like dark matter halo, extracted from a cosmological zoom-in simulation. For each snapshot, the density of the halo is reduced to a basis function expansion, with interpolation used to recreate the evolution between snapshots. The angular variation of the halo density is described by spherical harmonics, and the radial variation either by biorthonormal basis functions adapted to handle truncated haloes or by splines. High fidelity orbit reconstructions are attainable using either method with similar computational expense. We quantify how the error in the reconstructed orbits varies with expansion order and snapshot spacing. Despite the many possible biorthonormal expansions, it is hard to beat a conventional Hernquist-Ostriker expansion with a moderate number of terms ($\gtrsim15$ radial and $\gtrsim6$ angular). As two applications of the developed machinery, we assess the impact of the time-dependence of the potential on (i) the orbits of Milky Way satellites, and (ii) planes of satellites as observed in the Milky Way and other nearby galaxies. Time evolution over the last 5 Gyr introduces an uncertainty in the Milky Way satellites' orbital parameters of $\sim 15$ per cent, comparable to that induced by the observational errors or the uncertainty in the present-day Milky Way potential. On average, planes of satellites grow at similar rates in evolving and time-independent potentials. There can be more, or less, growth in the plane's thickness, if the plane becomes less, or more, aligned with the major or minor axis of the evolving halo

Models of Distorted and Evolving Dark Matter Halos

We investigate the ability of basis function expansions to reproduce the evolution of a Milky Way-like dark matter halo, extracted from a cosmological zoom-in simulation. For each snapshot, the density of the halo is reduced to a basis function expansion, with interpolation used to recreate the evolution between snapshots. The angular variation of the halo density is described by spherical harmonics, and the radial variation either by biorthonormal basis functions adapted to handle truncated haloes or by splines. High fidelity orbit reconstructions are attainable using either method with similar computational expense. We quantify how the error in the reconstructed orbits varies with expansion order and snapshot spacing. Despite the many possible biorthonormal expansions, it is hard to beat a conventional Hernquist-Ostriker expansion with a moderate number of terms ($\gtrsim15$ radial and $\gtrsim6$ angular). As two applications of the developed machinery, we assess the impact of the time-dependence of the potential on (i) the orbits of Milky Way satellites, and (ii) planes of satellites as observed in the Milky Way and other nearby galaxies. Time evolution over the last 5 Gyr introduces an uncertainty in the Milky Way satellites' orbital parameters of $\sim 15$ per cent, comparable to that induced by the observational errors or the uncertainty in the present-day Milky Way potential. On average, planes of satellites grow at similar rates in evolving and time-independent potentials. There can be more, or less, growth in the plane's thickness, if the plane becomes less, or more, aligned with the major or minor axis of the evolving halo.Comment: MNRAS, submitte

Coupled currents in cosmic strings

We first examine the microstructure of a cosmic string endowed with two simple Abelian currents. This microstructure depends on two state parameters. We then provide the macroscopic description of such a string and show that it depends on an additional Lorentz-invariant state parameter that relates the two currents. We find that in most of the parameter space, the two-current string is essentially equivalent to the single current-carrying string, i.e., only one field condenses onto the defect. In the regions where two currents are present, we find that as far as stability is concerned, one can approximate the dynamics with good accuracy using an analytic model based on either a logarithmic (on the electric side, i.e., for timelike currents) or a rational (on the magnetic side, i.e., for spacelike currents) worldsheet Lagrangian.Comment: 25 pages, 9 figure

DNA cruciform arms nucleate through a correlated but non-synchronous cooperative mechanism

Inverted repeat (IR) sequences in DNA can form non-canonical cruciform structures to relieve torsional stress. We use Monte Carlo simulations of a recently developed coarse-grained model of DNA to demonstrate that the nucleation of a cruciform can proceed through a cooperative mechanism. Firstly, a twist-induced denaturation bubble must diffuse so that its midpoint is near the centre of symmetry of the IR sequence. Secondly, bubble fluctuations must be large enough to allow one of the arms to form a small number of hairpin bonds. Once the first arm is partially formed, the second arm can rapidly grow to a similar size. Because bubbles can twist back on themselves, they need considerably fewer bases to resolve torsional stress than the final cruciform state does. The initially stabilised cruciform therefore continues to grow, which typically proceeds synchronously, reminiscent of the S-type mechanism of cruciform formation. By using umbrella sampling techniques we calculate, for different temperatures and superhelical densities, the free energy as a function of the number of bonds in each cruciform along the correlated but non-synchronous nucleation pathways we observed in direct simulations.Comment: 12 pages main paper + 11 pages supplementary dat

Rethinking animal models of sepsis - working towards improved clinical translation whilst integrating the 3Rs.

Sepsis is a major worldwide healthcare issue with unmet clinical need. Despite extensive animal research in this area, successful clinical translation has been largely unsuccessful. We propose one reason for this is that, sometimes, the experimental question is misdirected or unrealistic expectations are being made of the animal model. As sepsis models can lead to a rapid and substantial suffering - it is essential that we continually review experimental approaches and undertake a full harm:benefit impact assessment for each study. In some instances, this may require refinement of existing sepsis models. In other cases, it may be replacement to a different experimental system altogether, answering a mechanistic question whilst aligning with the principles of reduction, refinement and replacement (3Rs). We discuss making better use of patient data to identify potentially useful therapeutic targets which can subsequently be validated in preclinical systems. This may be achieved through greater use of construct validity models, from which mechanistic conclusions are drawn. We argue that such models could provide equally useful scientific data as face validity models, but with an improved 3Rs impact. Indeed, construct validity models may not require sepsis to be modelled, per se. We propose that approaches that could support and refine clinical translation of research findings, whilst reducing the overall welfare burden on research animals

Quark Masses: An Environmental Impact Statement

We investigate worlds that lie on a slice through the parameter space of the Standard Model over which quark masses vary. We allow as many as three quarks to participate in nuclei, while fixing the mass of the electron and the average mass of the lightest baryon flavor multiplet. We classify as "congenial" worlds that satisfy the environmental constraint that the quark masses allow for stable nuclei with charges one, six, and eight, making organic chemistry possible. Whether a congenial world actually produces observers depends on a multitude of historical contingencies, beginning with primordial nucleosynthesis, which we do not explore. Such constraints may be independently superimposed on our results. Environmental constraints such as the ones we study may be combined with information about the a priori distribution of quark masses over the landscape of possible universes to determine whether the measured values of the quark masses are determined environmentally, but our analysis is independent of such an anthropic approach. We estimate baryon masses as functions of quark masses and nuclear masses as functions of baryon masses. We check for the stability of nuclei against fission, strong particle emission, and weak nucleon emission. For two light quarks with charges 2/3 and -1/3, we find a band of congeniality roughly 29 MeV wide in their mass difference. We also find another, less robust region of congeniality with one light, charge -1/3 quark, and two heavier, approximately degenerate charge -1/3 and 2/3 quarks. No other assignment of light quark charges yields congenial worlds with two baryons participating in nuclei. We identify and discuss the region in quark-mass space where nuclei would be made from three or more baryon species.Comment: 40 pages, 16 figures (in color), 4 tables. See paper for a more detailed abstract. v4: Cleaning up minor typo