Efeito da profilaxia profissional e da escovação com dentifrício com ou sem flúor na remineralização do esmalte dental

An in situ evaluation of the potential rehardening effect of fluoridated and non-fluoridated toothpastes with or without air polishing was conducted. Ten volunteers, using acrylic palatal appliances containing two bovine enamel blocks with artificial carious lesions, took part in this study. Four times a day, after the main meals and at night, the volunteers, in a habitual way, brushed their natural teeth with the dentifrice indicated to the experimental design and after that the appliances were put again into the mouth. They were divided into 4 different groups: G1 - control - non-fluoridated dentifrice; G2 - fluoridated dentifrice; G3 - non-fluoridated dentifrice, but having a previous prophylaxis using air polishing; G4 - fluoridated dentifrice and previous air polishing. The effects of treatments on enamel rehardening were evaluated in the blocks that were assessed by surface microhardness, and the percentage of surface microhardness change (%reh) was calculated in relation to the baseline values. The results showed that %reh was higher in the groups with fluoridated dentifrice, and professional prophylaxis did not have an additional effect in the groups of fluoridated dentifrices (pO objetivo deste estudo foi avaliar, in situ, o potencial de remineralizaçaão do dentifrício fluoretado ou não, isoladamente ou associado à profilaxia profissional com jato de bicarbonato de sódio, em esmalte bovino com lesão superficial artificial de cárie. Utilizou-se 80 blocos de esmalte (4X4X2mm), nos quais foram realizadas medidas de microdureza superficial antes e após a desmineralização artificial e após o tratamento, com um penetrador, Knoop carga de 50/7s, para o cálculo do percentual de recuperação de dureza (%reh). Após as tomadas das 2 medidas de microdureza iniciais (antes e após a desmineralização), os blocos de esmalte foram incluídos em dispositivos intrabucais palatinos (2 blocos/aparelho). Dez jovens voluntários usaram estes dispositivos durante 10 dias com intervalo de 7 dias entre cada fase do experimento (estudo cruzado), realizando higiene bucal habitual (4X/dia, sendo 3 após as refeições e 1 à noite). Estabeleceu-se 4 grupos: G1-controle-escovação com dentifrício sem flúor; G2-escovação com dentifrício fluoretado; G3-antes da instalação do dispositivo realizou-se uma profilaxia com jato de bicarbonato de sódio e escovação com dentifrício sem flúor; G4-profilaxia e dentifrício fluoretado. A análise de variância (ANOVA, p=1,04 x 10-6) e o teste de Student-Newman-Keuls (

Granulomatous-like immune reaction and hepatic fibrosis induced by Schistosoma haematobium immature worms

Golden hamsters were inoculated with Schistosoma haematobium cercariae to examine histological lesions at different time points over an 18 month period of infection. Hamsters were sacrificed 26 weeks and 82 weeks after inoculation. The parasite was found in the blood and in the liver of infected animals as was expected, but we found exclusively male worms, no female worms nor eggs. Interestingly we observed unexpected hepatic lesions induced by S. haematobium immature male worms alone in the golden hamster, characteristic of schistosome eggs. Samples from liver, kidneys, lungs, bladder and gastrointestinal tract were collected during necropsy to evaluate injuries induced by S. haematobium. Notably we observed hepatitis in the liver of infected hamsters, no lesions were found in other organs. We also found liver fibrosis in infected hamsters. This study provides further experimental evidence for the role that schistosome worms, and their derived antigens, may play in the pathology of the infection and modulation of liver chronic inflammation in the murine model of schistosomiasis

Social distancing measures to control the COVID-19 pandemic: potential impacts and challenges in Brazil.

The COVID-19 pandemic has challenged researchers and policy makers to identify public safety measures forpreventing the collapse of healthcare systems and reducingdeaths. This narrative review summarizes the available evidence on the impact of social distancing measures on the epidemic and discusses the implementation of these measures in Brazil. Articles on the effect of social distancing on COVID-19 were selected from the PubMed, medRXiv and bioRvix databases. Federal and state legislation was analyzed to summarize the strategies implemented in Brazil. Social distancing measures adopted by the population appear effective, particularly when implemented in conjunction with the isolation of cases and quarantining of contacts. Therefore, social distancing measures, and social protection policies to guarantee the sustainability of these measures, should be implemented. To control COVID-19 in Brazil, it is also crucial that epidemiological monitoring is strengthened at all three levels of the Brazilian National Health System (SUS). This includes evaluating and usingsupplementary indicators to monitor the progression of the pandemic and the effect of the control measures, increasing testing capacity, and making disaggregated notificationsand testing resultstransparentand broadly available

NOTIFICAÇÃO DA COVID-19

Livro base do Curso MOOC “Fortalecimento das Instituições de Longa Permanência para Idoso (ILPI): combate à pandemia covid-19” disponível na UFPR Aberta

PREVENÇÃO E CONTROLE DA COVID-19 NAS ILPI

Livro base do Curso MOOC “Fortalecimento das Instituições de Longa Permanência para Idoso (ILPI): combate à pandemia covid-19” disponível na UFPR Aberta

TÓPICOS RELEVANTES NO CUIDADO COM O IDOSO

Livro base do Curso MOOC “Fortalecimento das Instituições de Longa Permanência para Idoso (ILPI): combate à pandemia covid-19” disponível na UFPR Aberta

AMBIENTE SEGURO NAS ILPI: BIOSSEGURANÇA, QUEDAS E IATROGENIAS

Livro base do Curso MOOC “Fortalecimento das Instituições de Longa Permanência para Idoso (ILPI): combate à pandemia covid-19” disponível na UFPR Aberta

EQUIPE, BIOSSEGURANÇA E GESTÃO DA ILPI

Livro base do Curso MOOC “Fortalecimento das Instituições de Longa Permanência para Idoso (ILPI): combate à pandemia covid-19” disponível na UFPR Aberta