1,066 research outputs found
Salt land survey, 1962 : report of a survey of soil salinity in the agricultural areas of Western Australia
IN Western Australia there are within the agricultural areas about one million acres of salt land, largely within the 14-25 inch rainfall area used for cereal and wool production.
In March, 1962, farmers in 68 shires in the agricultural areas of Western Australia estimated that on their properties 305,270 acres of land previously cropped or sown to pasture had become salt affected. Of this total, 59,203 acres had gone salt in the seven years immediately before the survey
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The influence of social status and ethnicity on diet in mediaeval Tallinn as seen through stable isotope analysis
© 2016, Estonian Academy Publishers. All rights reserved. Food encodes social and cultural values and has an important role to play in defining identities. In mixed populations, diet can be used to distinguish between ‘us’ and ‘them’. This study investigates the extent to which the inhabitants of mediaeval Tallinn, an important trading centre, used food to maintain distinct identities. Human skeletal material was selected from four mediaeval cemeteries in Tallinn, chosen to represent different groups within Tallinn’s society, likely including foreign merchants, foreign monks, urban Estonians and low-status Estonians, and from a nearby rural site, Kaberla, for comparative purposes. The individuals were investigated using carbon, nitrogen and oxygen stable isotope analysis. The results indicate that while all analysed individuals consumed diets based on C3 plants and animals consuming C3 plants, some individuals also consumed small amounts of C4 plants (likely millet) or seafood. C4 plants were consumed by the urban residents buried at the Church of the Holy Spirit and one or two individuals from Sulevimägi. It is thought that millet was an imported food consumed by the middle class. Marine foods were consumed by the individuals at St Catherine’s Church. These individuals were also identified as migrants and were likely either monks or foreign merchants. The results suggest that in some cases the people of Tallinn did use food as a means of maintaining social statuses and potentially ethnicities. Only one individual (LTL06) was identified as having had a significant change in diet during life, with the inclusion of marine foods in adulthood. This may indicate that this individual attained or aspired to higher social status during life and adhered to Christian dietary customs.We would like to thank Liina Maldre for her help with the animal remains and Raili Allmäe for their help with the human remains, also Mare Aun for consultations about Kaberla cemetery and Kaire Tooming for consultations about Pühavaimu cemetery. The authors would also like to thank Ligia Trombetta-Lima, Catherine Kneale and James Rolfe (University of Cambridge) for their help with isotopic sample analysis. Emma Lightfoot would like to thank Darwin College, University of Cambridge for financial support. The article was written by the support of research projects of the Estonian Ministry of Education and Science (ETF9405 and IUT18-8)
Definition of Soybean Genomic Regions That Control Seed Phytoestrogen Amounts
Soybean seeds contain large amounts of isoflavones or phytoestrogens such as genistein, daidzein, and glycitein that display biological effects when ingested by humans and animals. In seeds, the total amount, and amount of each type, of isoflavone varies by 5 fold between cultivars and locations. Isoflavone content and quality are one key to the biological effects of soy foods, dietary supplements, and nutraceuticals. Previously we had identified 6 loci (QTL) controlling isoflavone content using 150 DNA markers. This study aimed to identify and delimit loci underlying heritable variation in isoflavone content with additional DNA markers. We used a recombinant inbred line (RIL) population ([Formula: see text]) derived from the cross of “Essex” by “Forrest,” two cultivars that contrast for isoflavone content. Seed isoflavone content of each RIL was determined by HPLC and compared against 240 polymorphic microsatellite markers by one-way analysis of variance. Two QTL that underlie seed isoflavone content were newly discovered. The additional markers confirmed and refined the positions of the six QTL already reported. The first new region anchored by the marker BARC_Satt063 was significantly associated with genistein ([Formula: see text] , [Formula: see text]) and daidzein ([Formula: see text] , [Formula: see text]). The region is located on linkage group B2 and derived the beneficial allele from Essex. The second new region defined by the marker BARC_Satt129 was significantly associated with total glycitein ([Formula: see text] , [Formula: see text]). The region is located on linkage group D1a+Q and also derived the beneficial allele from Essex. Jointly the eight loci can explain the heritable variation in isoflavone content. The loci may be used to stabilize seed isoflavone content by selection and to isolate the underlying genes
Cs7Sm11[TeO3]12Cl16 and Rb7Nd11[TeO3]12Br16, the new tellurite halides of the tetragonal Rb6LiNd11[SeO3]12Cl16 structure type
The authors thank the Russian Foundation for Basic Researches for the support of this work under Grants No. 14-03-00604_a and 12-03-92604-KO_a. The X-ray study of compound II was made possible due to M.V. Lomonosov Moscow State University Programm of Development. PL thanks the University of St Andrews and EPSRC for DTA Studentships to CB and LJD.Two new rare-earth – alkali – tellurium oxide halides were synthesized by a salt flux technique and characterized by single-crystal X-ray diffraction. The structures of the new compounds Cs7Sm11[TeO3]12Cl16 (I) and Rb7Nd11[TeO3]12Br16 (II) (both tetragonal, space group I4/mcm) correspond to the sequence of [MLn11(TeO3)12] and [M6×16] layers and bear very strong similarities to those of known selenite analogs. We discuss the trends in similarities and differences in compositions and structural details between the Se and Te compounds; more members of the family are predicted.PostprintPeer reviewe
Chemopreventive Effects of the p53-Modulating Agents CP-31398 and Prima-1 in Tobacco Carcinogen-Induced Lung Tumorigenesis in A/J Mice
AbstractLung cancer is the leading cause of cancer deaths worldwide. Expression of the p53 tumor suppressor protein is frequently altered in tobacco-associated lung cancers. We studied chemopreventive effects of p53-modulating agents, namely, CP-31398 and Prima-1, on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung adenoma and adenocarcinoma formation in female A/J mice. Seven-week-old mice were treated with a single dose of NNK (10 µmol/mouse) by intraperitoneal injection and, 3 weeks later, were randomized to mice fed a control diet or experimental diets containing 50 or 100 ppm CP-31398 or 150 or 300 ppm Prima-1 for either 17 weeks (10 mice/group) or 34 weeks (15 mice/group) to assess the efficacy against lung adenoma and adenocarcinoma. Dietary feeding of 50 or 100 ppm CP-31398 significantly suppressed (P < .0001) lung adenocarcinoma by 64% and 73%, respectively, after 17 weeks and by 47% and 56%, respectively, after 34 weeks. Similarly, 150 or 300 ppm Prima-1 significantly suppressed (P < .0001) lung adenocarcinoma formation by 56% and 62%, respectively, after 17 weeks and 39% and 56%, respectively, after 34 weeks. Importantly, these results suggest that both p53 modulators cause a delay in the progression of adenoma to adenocarcinoma. Immunohistochemical analysis of lung tumors from mice exposed to p53-modulating agents showed a significantly reduced tumor cell proliferation and increased accumulation of wild-type p53 in the nucleus. An increase in p21- and apoptotic-positive cells was also observed in lung tumors of mice exposed to p53-modulating agents. These results support a chemopreventive role of p53-modulating agents in tobacco carcinogen-induced lung adenocarcinoma formation
Charge amplification concepts for direction-sensitive dark matter detectors
Direction measurement of weakly interacting massive particles in
time-projection chambers can provide definite evidence of their existence and
help to determine their properties. This article demonstrates several concepts
for charge amplification in time-projection chambers that can be used in
direction-sensitive dark matter search experiments. We demonstrate
reconstruction of the 'head-tail' effect for nuclear recoils above 100keV, and
discuss the detector performance in the context of dark matter detection and
scaling to large detector volumes.Comment: 15 pages, 9 figure
Measurements of Scintillation Efficiency and Pulse-Shape for Low Energy Recoils in Liquid Xenon
Results of observations of low energy nuclear and electron recoil events in
liquid xenon scintillator detectors are given. The relative scintillation
efficiency for nuclear recoils is 0.22 +/- 0.01 in the recoil energy range 40
keV - 70 keV. Under the assumption of a single dominant decay component to the
scintillation pulse-shape the log-normal mean parameter T0 of the maximum
likelihood estimator of the decay time constant for 6 keV < Eee < 30 keV
nuclear recoil events is equal to 21.0 ns +/- 0.5 ns. It is observed that for
electron recoils T0 rises slowly with energy, having a value ~ 30 ns at Eee ~
15 keV. Electron and nuclear recoil pulse-shapes are found to be well fitted by
single exponential functions although some evidence is found for a double
exponential form for the nuclear recoil pulse-shape.Comment: 11 pages, including 5 encapsulated postscript figure
Genomic regions that underlie soybean seed isoflavone content
Soy products contain isoflavones (genistein, daidzein, and glycitein)that display biological effects when ingested by humans and animals, these effects are species, dose and age dependent. Therefore, the content and quality of isoflavones in soybeans is a key to their biological effect. Our objective was to identify loci that underlie isoflavone content in soybean seeds. The study involved 100 recombinant inbred lines (RIL)fr om the cross of ‘Essex’ by ‘Forrest,’ two cultivars that contrast for isoflavone content. Isoflavone content of seeds fromeach RIL was determined by high performance liquid chromatography (HPLC). The distribution of isoflavone content was continuous and unimodal. The heritability estimates on a line mean basis were 79% for daidzein, 22% for genistein, and 88% for glycitein. Isoflavone content of soybean seeds was compared against 150 polymorphic DNA markers in a one-way analysis of variance. Four genomic regions were found to be significantly associated with the isoflavone content of soybean seeds across both locations and years. Molecular linkage group B1 contained a major QTL underlying glycitein content (P = 0.0001,R2 = 50.2%), linkage group N contained a QTL for glycitein (P = 0.0033,R2 = 11.1%)and a QTL for daidzein (P = 0.0023,R2 = 10.3%) and linkage group A1 contained a QTL for daidzein (P = 0.0081,R2 = 9.6%). Selection for these chromosomal regions in a marker assisted selection program will allow for the manipulation of amounts and profiles of isoflavones (genistein, daidzein, and glycitein)c ontent of soybean seeds. In addition, tightly linked markers can be used in map based cloning of genes associated with isoflavone content
N-terminal acetylation promotes synaptonemal complex assembly in C. elegans
N-terminal acetylation of the first two amino acids on proteins is a prevalent cotranslational modification. Despite its abundance, the biological processes associated with this modification are not well understood. Here, we mapped the pattern of protein N-terminal acetylation in Caenorhabditis elegans, uncovering a conserved set of rules for this protein modification and identifying substrates for the N-terminal acetyltransferase B (NatB) complex. We observed an enrichment for global protein N-terminal acetylation and also specifically for NatB substrates in the nucleus, supporting the importance of this modification for regulating biological functions within this cellular compartment. Peptide profiling analysis provides evidence of cross-talk between N-terminal acetylation and internal modifications in a NAT substrate-specific manner. In vivo studies indicate that N-terminal acetylation is critical for meiosis, as it regulates the assembly of the synaptonemal complex (SC), a proteinaceous structure ubiquitously present during meiosis from yeast to humans. Specifically, N-terminal acetylation of NatB substrate SYP-1, an SC structural component, is critical for SC assembly. These findings provide novel insights into the biological functions of N-terminal acetylation and its essential role during meiosis
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