The Organization of Words in Mental Lexicon: Evidence From Word Association Test

Both in psychology and linguistics studies, memory is one of the core of interests amongst researchers. In linguistics, memory is the place where language processes consisting of language perception, storage, and access of words take place. Words, in memory, are stored in complex, clear, well-organized, and ordered networks called nodes, which can be represented by World Wide Web. This word organization in psycholinguistics is referred to mental lexicon. This study aims to investigate what kind of nodes representation stored in mental lexicon of foreign language learners. Word Association Test (WAT), the well-known study method in both psychology and linguistics studies, is employed by using English Swadesh word list as the stimulus to elicit the lexical relation amongst words. The basic principle of the test is giving a stimulus to respondents and asking them to give the very first word coming out of their mind. Respondents are undergraduate students of English Literature a university in Indonesia. Findings of this research support the previous findings stating that non-native speakers tend to make syntagmatic relation, which is mostly dominated by collocation association. Interestingly, the finding also shows that the words network in mental lexicon involves a dynamic development based on experience and perception of the respondents

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes.

BackgroundDendritic simplification, a key feature of the neurodegenerative triad of Alzheimer's disease (AD) in addition to spine changes and neuron loss, occurs in a region-specific manner. However, it is unknown how changes in dendritic complexity are mediated and how they relate to spine changes and neuron loss.ResultsTo investigate the mechanisms of dendritic simplification in an authentic CNS environment we employed an ex vivo model, based on targeted expression of enhanced green fluorescent protein (EGFP)-tagged constructs in organotypic hippocampal slices of mice. Algorithm-based 3D reconstruction of whole neuron morphology in different hippocampal regions was performed on slices from APPSDL-transgenic and control animals. We demonstrate that induction of dendritic simplification requires the combined action of amyloid beta (Aβ) and human tau. Simplification is restricted to principal neurons of the CA1 region, recapitulating the region specificity in AD patients, and occurs at sites of Schaffer collateral input. We report that γ-secretase inhibition and treatment with the NMDA-receptor antagonist, CPP, counteract dendritic simplification. The microtubule-stabilizing drug epothilone D (EpoD) induces simplification in control cultures per se. Similar morphological changes were induced by a phosphoblocking tau construct, which also increases microtubule stability. In fact, low nanomolar concentrations of naturally secreted Aβ decreased phosphorylation at S262 in a cellular model, a site which is known to directly modulate tau-microtubule interactions.ConclusionsThe data provide evidence that dendritic simplification is mechanistically distinct from other neurodegenerative events and involves microtubule stabilization by dendritic tau, which becomes dephosphorylated at certain sites. They imply that treatments leading to an overall decrease of tau phosphorylation might have a negative impact on neuronal connectivity

Gestión estratégica de las estructuras académicas y administrativas, de la Universidad Católica de Santa Fe, para su adecuación al proceso de evaluación y acreditación

A partir de los años 80 comenzó a imponerse la necesidad de acordar criterios comunes respecto a los umbrales de la calidad educativa impartida por instituciones universitarias de todo el mundo. Nuestro país no quedó al margen de estas transformaciones, y comenzó el proceso con la promulgación de la legislación que fijara los criterios para la adecuación de la educación a los nuevos requerimientos de calidad. La sanción de la Ley N°24521 impulsó este cambio por el cual las universidades debieron adecuar sus estructuras académicas y administrativas para alcanzar los estándares impuestos por la acreditación. A través del presente trabajo comunicaremos la experiencia de la Universidad Católica de Santa Fe en el marco de este proceso

La transformación de los procesos de gestión de la información en la Universidad Católica de Santa Fe a partir de la incorporación de las nuevas tecnologías

La gestión de la información y los procesos de comunicación institucional constituyen uno de los pilares fundamentales en el desenvolvimiento de la vida de las universidades. A partir de la década del 80, estos procesos sufrieron importantes cambios en todo el mundo debido a la incorporación de las nuevas tecnologías. A través del siguiente trabajo comunicaremos los procesos de gestión de la información, a partir de la incorporación de las nuevas herramientas que ofrecen las tecnologías. Presentando nuestra experiencia desde la Universidad Católica de Santa Fe, las fortalezas y debilidades del modelo de gestión en vigencia. Y proponiendo un diseño de gestión de estos procesos que contemple un uso adecuado de, lo que se considera, las principales herramientas del cambio: correo electrónico, Web y mensajería

USING INSTAGRAM IN THE SPORTS BIOMECHANICS CLASSROOM

The main objective of the investigation was to evaluate the change in perception of students in the use of Instagram as a learning medium for qualitative biomechanical analysis as a part of their undergraduate sports science programme. 106 undergraduate students filled out a questionnaire on the use of smartphones, social networks and Instagram in a biomechanics classroom before and after participating in an assignment.The results of our study show the change in perspective in the participants about the use of social networks to do assignments, specifically in Biomechanics (PRE 3.0±1.4 vs POST 3.6±1.1,