1,214 research outputs found
Accelerated mechanical fatigue testing and lifetime of interconnects in microelectronics
AbstractDue to the rapid development of packaging industry accelerated reliability testing for evaluation of lifetime of electronic components are increasingly utilized. In addition to common active thermal cycling procedures, accelerated mechanical fatigue testing provides a new possibility to assess the reliability of microelectronic components, mainly due to the significantly shorter duration of testing time. In this investigation we have used an ultrasonic fatigue testing system in combination with a special experimental set-up for qualification and lifetime determination of microelectronic interconnects. Using this technique, fatigue life of Al wire bonded interconnects were determined and S-N curves (shear stress as a function of loading cycles) up to N=109 were plotted. Three dimensional elasto-plastic FEM simulations were performed to determine the distributions of shear stress and plastic strain generated during cyclic fatigue in the bond area. Furthermore, the FEM model was employed to predict the lifetime of wire-bonds. The results were correlated to the lifetime curves of similar bonds obtained by power cycling tests. Detailed microstructural investigations were performed by means of EBSD -SEM to study the evolution of microstructure of the interconnects subjected to thermal and mechanical fatigue loading. This study demonstrates the applicability of accelerated mechanical fatigue testing as an alternative to time consuming thermal cycling for qualification of microelectronic interconnects
VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis
Several factors are known to enhance adult hippocampal neurogenesis but a factor capable of inducing a long-lasting neurogenic enhancement that attenuates age-related neurogenic decay has not been described. Here, we studied hippocampal neurogenesis following conditional VEGF induction in the adult brain and showed that a short episode of VEGF exposure withdrawn shortly after the generation of durable new vessels (but not under conditions where newly made vessels failed to persist) is sufficient for neurogenesis to proceed at a markedly elevated level for many months later. Continual neurogenic increase over several months was not accompanied by accelerated exhaustion of the neuronal stem cell (NSC) reserve, thereby allowing neurogenesis to proceed at a markedly elevated rate also in old mice. Neurogenic enhancement by VEGF preconditioning was, in part, attributed to rescue of age-related NSC quiescence. Remarkably, VEGF caused extensive NSC remodelling manifested in transition of the enigmatic NSC terminal arbor onto long cytoplasmic processes engaging with and spreading over even remote blood vessels, a configuration reminiscent of early postnatal "juvenile" NSCs. Together, these findings suggest that VEGF preconditioning might be harnessed for long-term neurogenic enhancement despite continued exposure to an "aged" systemic milieu
Big sugar in southern Africa : rural development and the perverted potential of sugar/ethanol exports
This paper asks how investment in large-scale sugar cane production has contributed, and will contribute, to rural development in southern Africa. Taking a case study of the South African company Illovo in Zambia, the argument is made that the potential for greater tax revenue, domestic competition, access to resources and wealth distribution from sugar/ethanol production have all been perverted and with relatively little payoff in wage labour opportunities in return. If the benefits of agro-exports cannot be so easily assumed, then the prospective 'balance sheet' of biofuels needs to be re-examined. In this light, the paper advocates smaller-scale agrarian initiatives
Electro-Magnetic Nucleon Form Factors and their Spectral Functions in Soliton Models
It is demonstrated that in simple soliton models essential features of the
electro-magnetic nucleon form factors observed over three orders of magnitude
in momentum transfer are naturally reproduced. The analysis shows that
three basic ingredients are required: an extended object, partial coupling to
vector mesons, and relativistic recoil corrections. We use for the extended
object the standard skyrmion, one vector meson propagator for both isospin
channels, and the relativistic boost to the Breit frame. Continuation to
timelike leads to quite stable results for the spectral functions in the
regime from the 2- or 3-pion threshold to about two rho masses. Especially the
onset of the continuous part of the spectral functions at threshold can be
reliably determined and there are strong analogies to the results imposed on
dispersion theoretic approaches by the unitarity constraint.Comment: 24 pages, (RevTeX), 5 PS-figures; Data points in fig.2 and
corresponding references added. Final version, to be published in Z.Physik
Collision Chronology Along the İzmir‐Ankara‐Erzincan Suture Zone: Insights From the Sarıcakaya Basin, Western Anatolia
An edited version of this paper was published by AGU. Copyright 2019 American Geophysical Union.Debate persists concerning the timing and geodynamics of intercontinental collision, style of syncollisional deformation, and development of topography and fold‐and‐thrust belts along the >1,700‐km‐long İzmir‐Ankara‐Erzincan suture zone (İAESZ) in Turkey. Resolving this debate is a necessary precursor to evaluating the integrity of convergent margin models and kinematic, topographic, and biogeographic reconstructions of the Mediterranean domain. Geodynamic models argue either for a synchronous or diachronous collision during either the Late Cretaceous and/or Eocene, followed by Eocene slab breakoff and postcollisional magmatism.
We investigate the collision chronology in western Anatolia as recorded in the sedimentary archives of the 90‐km‐long Sarıcakaya Basin perched at shallow structural levels along the İAESZ. Based on new zircon U‐Pb geochronology and depositional environment and sedimentary provenance results, we demonstrate that the Sarıcakaya Basin is an Eocene sedimentary basin with sediment sourced from both the İAESZ and Söğüt Thrust fault to the south and north, respectively, and formed primarily by flexural loading from north‐south shortening along the syncollisional Söğüt Thrust. Our results refine the timing of collision between the Anatolides and Pontide terranes in western Anatolia to Maastrichtian‐Middle Paleocene and Early Eocene crustal shortening and basin formation. Furthermore, we demonstrate contemporaneous collision, deformation, and magmatism across the İAESZ, supporting synchronous collision models. We show that regional postcollisional magmatism can be explained by renewed underthrusting instead of slab breakoff. This new İAESZ chronology provides additional constraints for kinematic, geodynamic, and biogeographic reconstructions of the Mediterranean domain
Validation of Diffuse Correlation Spectroscopic Measurement of Cerebral Blood Flow Using Phase-Encoded Velocity Mapping Magnetic Resonance Imaging
Diffuse correlation spectroscopy (DCS) is a novel optical technique that appears to be an excellent tool for assessing cerebral blood flow in a continuous and non-invasive manner at the bedside. We present new clinical validation of the DCS methodology by demonstrating strong agreement between DCS indices of relative cerebral blood flow and indices based on phase-encoded velocity mapping magnetic resonance imaging (VENC MRI) of relative blood flow in the jugular veins and superior vena cava. Data were acquired from 46 children with single ventricle cardiac lesions during a hypercapnia intervention. Significant increases in cerebral blood flow, measured both by DCS and by VENC MRI, as well as significant increases in oxyhemoglobin concentration, and total hemoglobin concentration, were observed during hypercapnia. Comparison of blood flow changes measured by VENC MRI in the jugular veins and by DCS revealed a strong linear relationship, R = 0.88, p \u3c 0.001, slope = 0.91 ± 0.07. Similar correlations were observed between DCS and VENC MRI in the superior vena cava, R = 0.77, slope = 0.99 ± 0.12, p \u3c 0.001. The relationship between VENC MRI in the aorta and DCS, a negative control, was weakly correlated, R = 0.46, slope = 1.77 ± 0.45, p \u3c 0.001
A study of a wire-plate eletrostatic precipitator operating in the removal of polydispersed particles
Evaluating the Impacts of Subsidies on Innovation Activities in Germany
Innovations are a key factor to ensure the competitiveness of establishments as well as to enhance the growth and wealth of nations. But more than any other economic activity, decisions about innovations are plagued by failures of the market mechanism. As a response, public instruments have been implemented to stimulate private innovation activities. The effectiveness of these measures, however, is ambiguous and calls for an empirical evaluation. In this paper we make use of the IAB Establishment Panel and apply various microeconometric methods to estimate the effect of public measures on innovation activities of German establishments. We find that neglecting sample selection due to observable as well as to unobservable characteristics leads to an overestimation of the treatment effect and that there are considerable differences with regard to size class and betweenWest and East German establishments
Nucleon Charge and Magnetization Densities from Sachs Form Factors
Relativistic prescriptions relating Sachs form factors to nucleon charge and
magnetization densities are used to fit recent data for both the proton and the
neutron. The analysis uses expansions in complete radial bases to minimize
model dependence and to estimate the uncertainties in radial densities due to
limitation of the range of momentum transfer. We find that the charge
distribution for the proton is significantly broad than its magnetization
density and that the magnetization density is slightly broader for the neutron
than the proton. The neutron charge form factor is consistent with the Galster
parametrization over the available range of Q^2, but relativistic inversion
produces a softer radial density. Discrete ambiguities in the inversion method
are analyzed in detail. The method of Mitra and Kumari ensures compatibility
with pQCD and is most useful for extrapolating form factors to large Q^2.Comment: To appear in Phys. Rev. C. Two new figures and accompanying text have
been added and several discussions have been clarified with no significant
changes to the conclusions. Now contains 47 pages including 21 figures and 2
table
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