8 research outputs found
The orosomucoid 1 protein (α1 acid glycoprotein) is overexpressed in odontogenic myxoma
Odontogenic myxoma (OM) is a benign, but locally invasive, neoplasm occurring in the jaws. However, the molecules implicated in its development are unknown. OM as well as Dental Follicle (DF), an odontogenic tissue surrounding the enamel organ, is derived from ectomesenchymal/mesencyhmal elements. To identify some protein that could participate in the development of this neoplasm, total proteins from OM were
separated by two-dimensional electrophoresis and the profiles were compared with those obtained from DF, used
as a control
Fibroma osificante juvenil psamomatoide maxilar con quiste óseo aneurismático secundario. Reporte de un caso
El fibroma osificante juvenil psamomatoide es un tumor raro y de crecimiento progresivo de los huesos extragnáticos craneofaciales, con tendencia a un comportamiento agresivo localmente y a la recidiva. La caracterĂstica patognomĂłnica es la presencia de osificaciones esfĂ©ricas parecidas a los cuerpos de psamoma. Se han reportado algunos casos asociados a quiste Ăłseo aneurismático secundario. El tratamiento quirĂşrgico radical y el seguimiento clĂnico y radiográfico estricto parecen ser el abordaje de preferencia para estas lesiones. Se reporta un caso de un fibroma osificante juvenil psamomatoide maxilar, asociado a quiste Ăłseo aneurismático, en una paciente de 10 años de edad.The juvenile psammomatoid ossifying fibroma is a rare, progressive growing tumor of the extragnathic craniofacial bones, with tendency to an agressive behavior and recurrence. The pathognomonic histopathologic feature is the presence of spherical ossicles resembling to psammoma bodies. Some cases in association with a secondary aneurysmal bone cyst have been reported. The radical surgical treatment with a clinical and imaging follow-up appears to be the preferred approach for this lesions. We report a case of psammomatoid juvenile ossifying fibroma in the maxilla in association to secondary aneurysmal bone cyst in a 10-year-old female patient
ModificaciĂłn de procedimiento Dautrey en dislocaciĂłn recurrente mandibular.
El manejo de la dislocación recurrente mandibular, puede representar un reto para el Cirujano Maxilofacial. La decisión tomada debe ser de acuerdo a las demandas de cada caso en particular. El presente caso fue tratado quirúrgicamente mediante el procedimiento Dautrey, debido a la dislocación recurrente crónica unilateral derecha de la articulación temporomandibular. Este procedimiento no perturba el movimiento funcional normal de la articulación, por otra parte previene la excursión excesiva anterior del cóndilo. La técnica quirúrgica propuesta, presenta una modificación al procedimiento original. Con resultados finales favorables para la función
Angiomyxolipoma (Vascular Myxolipoma) of the Oral Cavity. Report of a Case and Review of the Literature
Angiomyxolipoma is a rare tumor characterized by a proliferation of adipose tissue associated with a myxoid stroma and multiple vascular channels. To date, ten cases of angiomyxolipoma located in subcutaneous tissue, spermatic cord and subungual area have been reported in the literature. We describe the clinical and histopathologic findings of the first case of intraoral angiomyxolipoma in a 12Â year-old male, as well as the utility of immunohistochemistry as a useful tool in differential diagnosis of this particular lesion with respect to other benign and malignant lesions derived from adipose tissue
Osteoma gigante en mandĂbula. Reporte de Caso.
El osteoma es una neoplasia benigna poco comĂşn, que se caracteriza por presentar un crecimiento Ăłseo progresivo, el cual está compuesto por la proliferaciĂłn bien diferenciada de hueso compacto y/o esponjoso. En el área maxilofacial se presenta con mayor frecuencia en la cara lingual posterior de la mandĂbula. Se caracteriza por crecimiento lento y asintomático. El caso describe una paciente de 45 años con un osteoma gigante mandibular de 4 años de evoluciĂłn tratado quirĂşrgicamente
Fibroma osificante juvenil psamomatoide maxilar con quiste óseo aneurismático secundario. Reporte de un caso
El fibroma osificante juvenil psamomatoide es un tumor raro y de crecimiento progresivo de los huesos extragnáticos craneofaciales, con tendencia a un comportamiento agresivo localmente y a la recidiva. La caracterĂstica patognomĂłnica es la presencia de osificaciones esfĂ©ricas parecidas a los cuerpos de psamoma. Se han reportado algunos casos asociados a quiste Ăłseo aneurismático secundario. El tratamiento quirĂşrgico radical y el seguimiento clĂnico y radiográfico estricto parecen ser el abordaje de preferencia para estas lesiones. Se reporta un caso de un fibroma osificante juvenil psamomatoide maxilar, asociado a quiste Ăłseo aneurismático, en una paciente de 10 años de edad
The orosomucoid 1 protein (α1 acid glycoprotein) is overexpressed in odontogenic myxoma
Abstract Background Odontogenic myxoma (OM) is a benign, but locally invasive, neoplasm occurring in the jaws. However, the molecules implicated in its development are unknown. OM as well as Dental Follicle (DF), an odontogenic tissue surrounding the enamel organ, is derived from ectomesenchymal/mesencyhmal elements. To identify some protein that could participate in the development of this neoplasm, total proteins from OM were separated by two-dimensional electrophoresis and the profiles were compared with those obtained from DF, used as a control. Results We identified eight proteins with differential expression; two of them were downregulated and six upregulated in OM. A spot consistently overexpressed in odontogenic myxoma, with a molecular weight of 44-kDa and a pI of 3.5 was identified as the orosomucoid 1 protein. Western blot experiments confirmed the overexpression of this protein in odontogenic myxoma and immunohistochemical assays showed that this protein was mainly located in the cytoplasm of stellate and spindle-shaped cells of this neoplasm. Conclusion Orosomucoid 1, which belongs to a group of acute-phase proteins, may play a role in the modulation of the immune system and possibly it influences the development of OM.</p