65 research outputs found

    Ecological-economic monitoring as a function of social-oriented management of the enterprise

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    The article deals with the need to create ecological and economic monitoring models within the framework of social and ecologically oriented construction company. Describes ecological and economic system management tools based on the new methodology creation integrated ecological-economic monitoring system

    Оценка работы очистных сооружений от нефтепродуктов и взвешенных веществ

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    Объект исследования являются очистные сооружения атмосферных и производственных нефтесодержащих стоков Анжеро-Судженской линейной производственной диспетчерской станции. Целью работы является оценка работы системы ? очистки сточных вод от взвешенных веществ и нефтепродуктов АЛПДС и возможности квалифицированного использования нефте-продуктов.Object of research are wastewater treatment plants atmospheric and industrial oily waste Anzhero-Sudzhensk line operation dispatcher station. The purpose of the work is to evaluate the operation of the system ? treatment of wastewater from suspended solids and oil lods and the possibility of qualified use of oil products

    A comparative analysis of agile methodologies development of Process Control System

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    The paper presents a comparative analysis of agile development methodologies APCS. You can find descriptions of modern methodologies, principles and techniques

    Microstructure analysis of titanium oxynitride films deposited by reactive magnetron sputtering

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    This paper presents the structure analysis results of TiOxNy films, deposited using reactive magnetron sputtering with different O2/N2 flow ratio. The impact of increase of N2 flow upon the films structure has been studied. The analysis was carried out by X-ray diffraction method. The lattice parameters and phase composition were calculated using PowderCell 2.4

    Методы ремонта дефектных участков линейной части магистральных газопроводов

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    В процессе исследования были рассмотрены методы обследования, и ремонта дефектных участков линейной части магистральных газопроводов, с целью выявления эффективных методов ремонта с учетом рекомендации ДДО. Так как сканер дефектоскоп с некоторой не точностью показывает расположение и размер дефектов, а также при обследовании бывает, что дефекты не подтверждаются.In the process of investigation, the methods of inspection and repair of defective sections of the linear part of the main gas pipelines were considered, in order to identify effective repair methods, taking into account the recommendation of the ADC. Since the scanner flaw detector with some inaccuracy shows the location and size of defects, and also during the inspection it happens that the defects are not confirmed

    Применение импульсного питания для сварки магистральных трубопроводов

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    Был проведен анализ напряженно-деформированных состояний моделей магистрального трубопровода, со сварным швом выполненным с разделкой кромок под шестьдесят градусов сваркой в СО2 и со сварным швом выполненным сваркой с применением импульсного питания в среде СО2 со щелевой разделкой кромок. Так же были рассчитаны некоторые параметры создания сварных соединений.An analysis was made of the stress-strain states of models of the main pipeline, with a welded seam made with cutting edges at sixty degrees by welding in CO2 and with a welded weld made using pulsed power in a CO2 medium with slotted cutting edges. Also, some parameters for creating welded joints were calculated

    Gene expression profiling of mucinous ovarian tumors and comparison with upper and lower gastrointestinal tumors identifies markers associated with adverse outcomes.

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    PURPOSE: Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis and lacks biomarkers to aid stage I adjuvant treatment. Differentiating primary MOC from gastrointestinal (GI) metastases to the ovary is also challenging due to phenotypic similarities. Clinicopathologic and gene-expression data were analyzed to identify prognostic and diagnostic features. EXPERIMENTAL DESIGN: Discovery analyses selected 19 genes with prognostic/diagnostic potential. Validation was performed through the Ovarian Tumor Tissue Analysis consortium and GI cancer biobanks comprising 604 patients with MOC (n = 333), mucinous borderline ovarian tumors (MBOT, n = 151), and upper GI (n = 65) and lower GI tumors (n = 55). RESULTS: Infiltrative pattern of invasion was associated with decreased overall survival (OS) within 2 years from diagnosis, compared with expansile pattern in stage I MOC [hazard ratio (HR), 2.77; 95% confidence interval (CI), 1.04–7.41, P = 0.042]. Increased expression of THBS2 and TAGLN was associated with shorter OS in MOC patients (HR, 1.25; 95% CI, 1.04–1.51, P = 0.016) and (HR, 1.21; 95% CI, 1.01–1.45, P = 0.043), respectively. ERBB2 (HER2) amplification or high mRNA expression was evident in 64 of 243 (26%) of MOCs, but only 8 of 243 (3%) were also infiltrative (4/39, 10%) or stage III/IV (4/31, 13%). CONCLUSIONS: An infiltrative growth pattern infers poor prognosis within 2 years from diagnosis and may help select stage I patients for adjuvant therapy. High expression of THBS2 and TAGLN in MOC confers an adverse prognosis and is upregulated in the infiltrative subtype, which warrants further investigation. Anti-HER2 therapy should be investigated in a subset of patients. MOC samples clustered with upper GI, yet markers to differentiate these entities remain elusive, suggesting similar underlying biology and shared treatment strategies
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